| Project/Area Number |
21590620
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Chiba Institute of Science |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAMEKO Fumiko 信州大学, 医学部, 助教 (60126670)
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| Research Collaborator |
ISHIGAKI Hironao 名古屋掖済会病院, 検査部, 臨床検査技師
ABE Masahito 栄研化学, マーケティング推進室, 臨床検査技師
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
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| Keywords | 免疫血清学 / 臨床化学 / 免疫グロブリン |
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| Research Abstract |
Routinely examination, there are many that show abnormal values not reflect the disease for measuring reagent to react with an abnormal protein(especially immunoglobulins). We analyzed the two cases of abnormal immunoglobulins, one case was found to be due to ionic bond with the sulfate group of an agar gel component and the patientγchain of IgG molecules. Another case, it is due to hydrophobic bonding with a linear alkyl group of SDS that is included in the reagent for measuring bilirubin and the patientμchain of IgM molecules was revealed.
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