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Utility of separation technique of live cancer stem cells with using an energy transfer fluorescence probes

Research Project

Project/Area Number 21590622
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory medicine
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

TAKESHITA Akihiro  浜松医科大学, 医学部, 准教授 (00242769)

Co-Investigator(Kenkyū-buntansha) OHNISHI Kazunori  浜松医科大学, 医学部附属病院, 教授 (80252170)
竹下 香 (新庄 香)  浜松医科大学, 保健管理センター, 特任助教 (30397393)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsエネルギー移行 / cell sorter / mRNA / 白血病 / 幹細胞 / FRET法 / KRAS / 癌細胞 / 白血病細胞 / bcr-abl / Kras / 肝細胞
Research Abstract

QUAL/FRET method is effective to determine the cells in which have specific mRNA. In this study, we examined the efficacy on insertion of probes using fluorescein labeled dextran firstly. Relatively high molecular ones did not enter into nucleus and distributed in cytoplasm. On the other hand, the efficacy of the insertion was studied in cell lines and peripheral blood cells. The efficacy was not sufficient in adherent cells and lymphocytes. It should be improved by changing molecular size of probe and conjugated fluorescence.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (47 results)

All 2011 2010 2009 Other

All Journal Article (17 results) (of which Peer Reviewed: 9 results) Presentation (28 results) Book (2 results)

  • [Journal Article] Japan Adult Leukemia Study Group. Impact of additional chromosomal abnormalities in patients with acute promyelocytic leukemia : 10-year results of the Japan Adult Leukemia Study Group APL97study2011

    • Author(s)
      Ono T, Takeshita A, Iwanaga M, Asou N, Naoe T, Ohno R
    • Journal Title

      Haematologica

      Volume: 96 Pages: 174-176

    • Related Report
      2011 Final Research Report
  • [Journal Article] for the Japan Adult Leukemia Study Group. Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia(AML): Japan Adult Leukemia Study Group(JALSG)-AML206 study2011

    • Author(s)
      Usui N, Takeshita A, Nakaseko C, Dobashi N, Fujita H, Kiyoi H, Kobayashi Y, Sakura T, Yahagi Y, Shigeno K, Ohwada C, Miyazaki Y, Ohtake S, Miyawaki S, Naoe T, Ohnishi K
    • Journal Title

      Cancer Sci

      Volume: 102 Pages: 1358-1365

    • Related Report
      2011 Final Research Report
  • [Journal Article] Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia (AML) : Japan Adult Leukemia study Group (JALSG)-AML206 study2011

    • Author(s)
      Usui N, Ohnishi K, et al
    • Journal Title

      Cancer Science

      Volume: 102(7) Issue: 7 Pages: 1358-65

    • DOI

      10.1111/j.1349-7006.2011.01957.x

    • NAID

      10029295449

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of additional chromosomal abnormalities in patients with acute promyelocytic leukemia : 10-year results of the Japan Adult Leukemia Study Group APL97 study2011

    • Author(s)
      Ono T, Takeshita A, et al
    • Journal Title

      Haematologica

      Volume: 96(1) Issue: 1 Pages: 174-6

    • DOI

      10.3324/haematol.2010.030205

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MEDICAL TECHNOLOGISTS AT UNIVERSITY HOSPITAL BLOOD TRANSFUSION DEPARTMENTS PLAY AN IMPORTANT ROLE IN EDUCATION IN TRANSFUSION MEDICINE: THE 2009 TRANSFUSION CONFERENCE OF JAPANESE UNIVERSITY HOSPITALS. SURVEILLANCE REPORT ON MEDICAL EDUCATION (1)2011

    • Author(s)
      Fujihara H, Takeshita A, et al
    • Journal Title

      Japanese Journal of Transfusion and Cell Therapy

      Volume: 57 Issue: 6 Pages: 470-477

    • DOI

      10.3925/jjtc.57.470

    • NAID

      130004542649

    • ISSN
      1881-3011, 1883-0625
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of additional chromosomal abnormalities in patients with acute promyelocytic leukemia : 10-year results of the Japan Adult Leukemia Study Group APL97 study.2011

    • Author(s)
      Ono T, Takeshita A, et al
    • Journal Title

      Haematologica

      Volume: 96(1) Pages: 174-176

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Collaborative study of irregular erythrocyte antibodies in Japan : results from the Japanese study group of allo-immunity and antigen diversity in Asian populations2010

    • Author(s)
      Takeshita A, Watanabe H, Fijihara H, Oshida M, Yurugi K, Tomoda Y, Uchikawa M, Kino S, Ohto H
    • Journal Title

      Transfus Apher Sci

      Volume: 43 Pages: 3-8

    • Related Report
      2011 Final Research Report
  • [Journal Article] Collaborative study of irregular erythrocyte antibodies in Japan : results from the Japanese study group of allo-immunity and antigen diversity in Asian populations.2010

    • Author(s)
      Takeshita A, et al
    • Journal Title

      Transfus Apheresis Sciences

      Volume: 43(1) Pages: 3-8

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CMC-544(inotuzumab ozogamicin) shows less effect on multidrug resistant cells : analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma2009

    • Author(s)
      Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R
    • Journal Title

      Br J Haematol

      Volume: 146(1) Pages: 34-43

    • Related Report
      2011 Final Research Report
  • [Journal Article] Effective Blood Utilization via System for Massive Blood Transfusion, including Cardiovascular Operation in Local Areas2009

    • Author(s)
      Takeshita A, Asai T, Murakami M, Fujihara H, Ishizuka T, Nakai S, Yamada C, Suzumura T, Uchiyama Y, Maekawa M, Shigeno K, Washiyama N, Yamashita K, Unno N, Shinjo K
    • Journal Title

      Jpn J Transfusion Cell Therapy

      Volume: 55(1) Pages: 63-7

    • NAID

      10025628900

    • Related Report
      2011 Final Research Report
  • [Journal Article] CMC-544(inotuzumab ozogamicin), an anti-CD22immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells2009

    • Author(s)
      Takeshita A, Yamakage N, Shinjo K, Ono T, Hirano I, Nakamura S, Shigeno K, Tobita T, Maekawa M, Kiyoi H, Naoe T, Ohnishi K, Sugimoto Y, Ohno R
    • Journal Title

      Leukemia

      Volume: 23(7) Pages: 1329-36

    • Related Report
      2011 Final Research Report
  • [Journal Article] Phase I/II study of humanized anti-CD33antibody conjugated with calicheamicin, gemtuzumab ozogamicin, in relapsed or refractory acute myeloid leukemia : final results of Japanese multicenter cooperative study2009

    • Author(s)
      Kobayashi Y, Tobinai K, Takeshita A, Naito K, Asai O, Dobashi N, Furusawa S, Saito K, Mitani K, Morishima Y, Ogura M, Yoshiba F, Hotta T, Bessho M, Matsuda S, Takeuchi J, Miyawaki S, Naoe T, Usui N, Ohno R
    • Journal Title

      Int J Hematol

      Volume: 89(4) Pages: 460-9

    • NAID

      10025161243

    • Related Report
      2011 Final Research Report
  • [Journal Article] CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells : analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma2009

    • Author(s)
      Takeshita A, et al.
    • Journal Title

      Br J Haematol 146

      Pages: 34-43

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells2009

    • Author(s)
      Takeshita A, et al.
    • Journal Title

      Leukemia 23

      Pages: 1329-1336

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase I/II study of humanized anti-CD33 antibody conjugated with calicheamicin, gemtuzumab ozogamicin, in relapsed or refractory acute myeloid leukemia : final results of Japanese multicenter cooperative study2009

    • Author(s)
      Kobayashi Y, et al.
    • Journal Title

      Int J Hematol 89

      Pages: 460-469

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effective Blood Utilization via System for Massive Blood Transfusion, including Cardiovascular Operation in Local Areas2009

    • Author(s)
      Takeshita A, et al.
    • Journal Title

      Jpn J Transfusion Cell Therapy 55

      Pages: 63-7

    • NAID

      10025628900

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Education in transfusion medicine for medical students and doctors

    • Author(s)
      Takeshita A, Yoneyama Y, Fujihara H, Nollet KE, Ohto H
    • Journal Title

      Vox Sanguinis

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Presentation] Efficacy of gemtuzumab ozogamicin(GO) on relapsed/refractory acute promyelocytic leukemia(APL)2011

    • Author(s)
      Takeshita A, Ono T, Kojima Y, Kyo T, Asou N, Suzushima H, Yagasaki H, Maeda T, Okada M, Nakaseko C, Kanbayashi H, Yamaguchi M, Kurosawa M, Tsuboi K, Yjiri T, Nanya Y, UikeN, Akiyama N, Fukuda T, Karimata K, Okumura H, Eto T, Izumiyama K, Watanabe A, Aotsuka N, Ito K, Ozaki K, Naoe T
    • Organizer
      53rd Annual Meeting of American Society of Hematology San Diego
    • Place of Presentation
      CA, USA
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Differences in allo-immunity to erythrocytes between Korea and Japan. Cooperative international study of alloimmunity to antigen diversity in Asian population2011

    • Author(s)
      Fujihara H, Takeshita A, Kim DW, Han KS, Kwon SY, Kwon SW, Suh JS, Watanabe H, Uchikawa M, Kino S, Nollet KE, Ohto H
    • Organizer
      53rd Annual Meeting of American Society of Hematology San Diego
    • Place of Presentation
      CA, USA
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Clinical features and prognostic impact of CD56expression in acute promyelocytic leukemia : Long term follow up data from the Japan Adult Leukemia Study Group(JALSG) APL972011

    • Author(s)
      Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Yamauchi T, Tsuzuki M, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Yagasaki F, Kimura Y, Fujita H, Iwanaga M, Asou N, Ohnishi K, Naoe T
    • Organizer
      53rd Annual Meeting of American Society of Hematology San Diego
    • Place of Presentation
      CA, USA
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Role of hematopoietic stem cell transplantation as salvage treatment of acute promyelocytic leukemia initially treated with all-trans retinoic acid : a retrospective analysis of the Japan Adult Leukemia Study Group(JALSG) APL97Study2011

    • Author(s)
      Fujita H, Asou N, Iwanaga M, Hyo R, Nomura S, Kiyoi H, Okada M, Tsuzuki M, Matsuda M, Yamauchi T, Ohtake S, Izumi T, Nakaseko C, Mitani K, Shinagawa K, Takeshita A, Miyazaki Y, Ohnishi K, Miyawaki S, Naoe T
    • Organizer
      53rd Annual Meeting of American Society of Hematology San Diego
    • Place of Presentation
      CA, USA
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] The usefulness and demerit of the expected elevation value of serum albumin before replacement therapy2011

    • Author(s)
      Fujihara H, Yamada C, Watanabe H, Shibata H, Funai Y, Suzumura T, Kaneko M, Uchiyama S, Takeshita A
    • Organizer
      16th Congress of the European Hematology Association
    • Place of Presentation
      London, UK
    • Year and Date
      2011-06-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Allo-Immunity to Erythrocytes in Relation to Blood Transfusion and Pregnancy ; Report from the Asian Cooperative Group2011

    • Author(s)
      Takeshita A
    • Organizer
      30^<th> Annual Meeting of Korean Society of Blood Transfusion
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2011-06-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Our role in promoting a better understanding of the efficacy of cryoprecipitate in acquired hypofibrinoginemia induced by perioperative massive bleeding2011

    • Author(s)
      Yamada C, Fujihara H, Watanabe H, Takeshita A
    • Organizer
      International Society of Blood Transfusion
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2011-06-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Allo-Immunity to Erythrocytes in Relation to Blood Transfusion and Pregnancy ; Report from the Asian Cooperative Group2011

    • Author(s)
      Takeshita A, et al
    • Organizer
      30^<th> Annual Meeting of Korean Society of Blood Transfusion
    • Place of Presentation
      Busa, Korea
    • Related Report
      2011 Annual Research Report
  • [Presentation] Efficacy of gemtuzumab ozogamicin (GO) on relapsed/refractory acute promyelocytic leukemia (APL)2011

    • Author(s)
      Takeshita A, et al
    • Organizer
      Annual Meeting of American Society of Hematology
    • Place of Presentation
      San Diego, USA
    • Related Report
      2011 Annual Research Report
  • [Presentation] Results of the multi-institutional surveys for the 21st Transfusion Conference of Japanese University Hospitals2010

    • Author(s)
      Fujihara H, Takeshita A, Watanabe H, Suzumura T, Oshida M, Yurugi K, Tomoda Y, Ohto H
    • Organizer
      the AABB Annual Meeting and CTTXPO
    • Place of Presentation
      Baltimore, Maryland, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Impact of additional chromosomal abnormalities(ACAs) in patients of acute promyelocytic leukemia10years follow up results of the Japan Adult Leukemia Study Group APL97study2010

    • Author(s)
      Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Kawai Y, Tsuzuki M, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Yagasaki F, Kimura Y, Iwanaga M, Asou N, Naoe T, Ohno R
    • Organizer
      15th Congress of the European Hematology Association
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2011 Final Research Report
  • [Presentation] Clinical Features and Outcomes of Elderly Patients with Acute Promyelocytic Leukemia(APL)-the Japan Adult Leukemia Study Group APL97Study2010

    • Author(s)
      Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Kawai Y, Tsuzuki M, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Yagasaki F, Kimura Y, Iwanaga M, Asou N, Naoe T, Ohno R
    • Organizer
      52nd annual meeting of American Society of Hematology
    • Place of Presentation
      Orland, FL, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Erythrocyte alloimmunization analyzed by gender and transfusion status2010

    • Author(s)
      Takeshita A, Watanabe H, Fujihara H, Oshida M, Yurugi K, Tomoda Y, Uchikawa M, Kino S, Nollet KE, Ohto H
    • Organizer
      52nd American Society
    • Place of Presentation
      Orland, FL, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Erythrocyte allo-immunization analyzed by gender and transfusion status2010

    • Author(s)
      Takeshita A, et al
    • Organizer
      52^<nd> Annual Meeting of American Society of Hematology
    • Place of Presentation
      Orange County Convention Center, Orland, Florida
    • Related Report
      2010 Annual Research Report
  • [Presentation] Clinical features and outcomes in elderly patients with acute promyelocytic leukemia -the Japan Adult Leukemia Study Group APL97 study-2010

    • Author(s)
      Ono T, Takeshita A, et al
    • Organizer
      American Society of Hematology (ASH) Annual Meeting and Exposition (52nd)
    • Place of Presentation
      Orange County Convention Center, Orlando, Florida
    • Related Report
      2010 Annual Research Report
  • [Presentation] Collaborative Study Group of Allo-immunity to Antigen Diversity in Asian Populations. Allo-immunity to erythrocytes in relation to blood transfusion and pregnancy ; Cooperative study of allo-immunity to antigen diversity in Asian populations2009

    • Author(s)
      Takeshita A, et al.
    • Organizer
      51th Annual Meeting of the American Society of Hematology
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Collaborative study on erythrocyte irregular antibodies in Japan Results from Japanese Study Group of Allo-Immunity to Antigen Diversity in Asian populations2009

    • Author(s)
      Takeshita A, et al.
    • Organizer
      20^<th> Congress of International Society of Blood Transfusion
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2009-11-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Internalization may be important in the efficacy of CMC-544, a new calicheamicin-conjugated anti-CD22 antibody2009

    • Author(s)
      Takeshita A, et al.
    • Organizer
      68^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] CMC-544, an anti-CD22 immuno-conjugate of calicheamicin, decreases the level of compliment inhibitory factors on malignant B-cell lymphoma cells2009

    • Author(s)
      Takeshita A, et al.
    • Organizer
      14^<th> congress of European Society of Hematology
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2009-06-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Internalization speed may be one of the factors in the efficacy of CMC-544(inotuzumab ozogamicin), the newly developed calicheamicin-conjugated antibody2009

    • Author(s)
      Takeshita A, Shinjo K, Watanabe Y, Maekawa M, Ohnishi K, Sugimoto Y, Ohno R
    • Organizer
      68th Annual Meeting of Japanese Cancer Society
    • Place of Presentation
      Yokohama
    • Related Report
      2011 Final Research Report
  • [Presentation] The role of medical technologists on the education of transfusion medicine : Results of the multi-institutional surveys for the 21th Transfusion Conference of University Hospitals in Japan2009

    • Author(s)
      Watanabe H, Takeshita A, Oshida M, Fujihara H, Tomoda Y, Yurugi K Ohto H
    • Organizer
      20th Congress of International Society of Blood Transfusion
    • Place of Presentation
      Nagoya
    • Related Report
      2011 Final Research Report
  • [Presentation] Collaborative study on erythrocyte irregular antibodies in Japan Results from Japanese Study Group of Allo-Immunity to Antigen Diversity in Asian populations2009

    • Author(s)
      Takeshita A, Watanabe H, Oshida M, Yurugi K, Tomoda Y, Uchikawa M, Kino S, Ohto H
    • Organizer
      20th Congress of International Society of Blood Transfusion
    • Place of Presentation
      Nagoya
    • Related Report
      2011 Final Research Report
  • [Presentation] Collaborative Study Group of Allo-immunity to Antigen Diversity in Asian Populations. Differences in allo-immunity to erythrocytes in Asian countries ; Cooperative study of allo-immunity to antigen diversity in Asian populations2009

    • Author(s)
      Watanabe H, Takeshita A, Kim DW, Han KS, Kwon SY, Suh JS, Natalie CPH, Nadarajan VS, Permpikul P, Nuranissa Bte Yacob Marican NBY, Uchikawa M, Kino S, Ohto H
    • Organizer
      51st Annual Meeting of the American Society of Hematology
    • Place of Presentation
      New Orleans, LA, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Collaborative Study Group of Allo-immunity to Antigen Diversity in Asian Populations. Allo-immunity to erythrocytes in relation to blood transfusion and pregnancy ; Cooperative study of allo-immunity to antigen diversity in Asian populations2009

    • Author(s)
      Takeshita A, Watanabe H, Kim DW, Han KS, Kwon SY, Suh JS, Natalie CPH, Nadarajan VS, Permpikul P, Nuranissa Bte Yacob Marican NBY, Uchikawa M, Kino S, Ohto H
    • Organizer
      51st Annual Meeting of the American Society of Hematology
    • Place of Presentation
      Orleans, LA, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] CMC-544, an anti-CD22immunoconjugate of calicheamicin, decreases the level of compliment inhibitory factors on malignant B-cell lymphoma cells2009

    • Author(s)
      Takeshita A, Yamakage N, Shinjo K, Hirano I, Ono T, Fujihara H, Watanabe H, Iino K, Hashimoto D, Maekawa M, Ohnishi K, Ohno R
    • Organizer
      14nd Congress of European Society of Hematology
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2011 Final Research Report
  • [Presentation] A Phase I/II Trial of Gemtuzumab Ozogamicin in Combination with Cytarabine and Anthracyclines(Daunorubicin or Idarubicin) for CD33-Positive Refractory or Relapsed AML Patients Younger Than65Years. Results of Phase I Parts of the JALSG-AML206Study2009

    • Author(s)
      Usui N, Takeshita A, Nakaseko C, Dobashi N, Fujita H, Kiyoi H, Kobayashi Y, Fujisawa S, Yagasaki F, Nishii K, Kiguchi T, Miyazaki Y, Ohtake S, Miyawaki S, Ohno R, Naoe T, Ohnishi K
    • Organizer
      51st Annual Meeting of the American Society of Hematology
    • Place of Presentation
      New Orleans, LA, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Collaborative Study Group of Allo-immunity to Antigen Diversity in Asian Populations : Differences in allo-immunity to erythrocytes in Asian countries ; Cooperative study of allo-immunity to antigen diversity in Asian populations2009

    • Author(s)
      Watanabe H, Takeshita A, Kim DW, Han KS, Kwon SY, Suh JS, Natalie CPH, Nadarajan VS, Permpikul P, Nuranissa Bte Yacob Marican NBY, Uchikawa M, Kino S, Ohto H
    • Organizer
      51st Annual Meeting of the American Society of Hematology
    • Place of Presentation
      New Orleans, LA, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] The role of medical technologists on the education of transfusion medicine : Results of the multi-institutional surveys for the21th Transfusion Conference of University Hospitals in Japan2009

    • Author(s)
      Watanabe H, Takeshita A, Oshida M, Fujihara H, Tomoda Y, Yurugi K Ohto H
    • Organizer
      20th Congress of International Society of Blood Transfusion
    • Place of Presentation
      Nagoya
    • Related Report
      2011 Final Research Report
  • [Book] APLにおけるレチノイン酸症候群とケモカイン産生2010

    • Author(s)
      竹下明裕
    • Total Pages
      5
    • Publisher
      血液・腫瘍科
    • Related Report
      2010 Annual Research Report
  • [Book] 血液疾患における分子標的治療 ドラッグラグ解消に向けて 白血病急性前骨髄球性白血病に対するレチノイン酸Am80 最近の進展2010

    • Author(s)
      竹下明裕
    • Total Pages
      6
    • Publisher
      血液フロンティア
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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