Study on early diagnosis of hypercoagulable state and mechanism for the onset in thrombosis

• Project/Area Number: 21590623
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Laboratory medicine
• Research Institution: Mie University
• Principal Investigator: WADA Hideo 三重大学, 大学院・医学系研究科, 准教授 (40158704)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 血栓症 / 過凝固症 / 播種性血管内凝固 / 深部静脈血栓症 / 肺塞栓症 / 可溶性フィブリン / D-dimer / 組織因子

Research Abstract

Elevated hemostatic molecular markers and decreased anticoagulant factors are observed in the onset of thrombosis, thus suggesting that these markers are useful for both making diagnosis of thrombosis and predicting the outcome or efficacy of treatment. Not only hereditary deficiencies of anticoagulant factor such as protein S Tokushima but also secondary deficiencies of anticoagulant factor are frequently observed in the patients with thrombosis. Data from the monitoring of anticoagulant therapy suggest that elevated fibrinolysis may be more important than the anti-Xa activity for assessing major bleeding.

Research Products

• [Journal Article] Frequent association of thrombophilia in cerebral venous sinus thrombosis (2012)
  • Author(s): Ikejiri M, Shindo A, Ii Y, Tomimoto H, Yamada N, Matsumoto T, Abe Y, Nakatani K, Nobori T, Wada H.
  • Journal Title: Int J Hematol Volume: 95 Pages: 257-262
  • NAID: 10030551794
  • Peer Reviewed
• [Journal Article] Increased fibrinolysis increases bleeding in orthopedic patients receiving prophylactic fondaparinux (2012)
  • Author(s): Yoshida K, Wada H, Hasegawa M, Wakabayashi H, Matsumoto T, Shimokariya Y, Noma K, Yamada N, Uchida A, Nobori T, Sudo A.
  • Journal Title: Int J Hematol Volume: 95 Pages: 160-166
  • NAID: 10030267312
  • Peer Reviewed
• [Journal Article] A novel protein S gene mutation combined with protein S Tokushima mutation in a patient with superior sagittal sinus thrombosis (2012)
  • Author(s): Shindo A, Ikejiri M, Ii Y, Nakatani K, Wada H, Nobori T, Tomimoto H.
  • Journal Title: J Neurol Volume: 259 Pages: 178-9
  • Peer Reviewed
• [Journal Article] Plasma ADAMTS13, von Willebrand Factor(VWF) and VWF Propeptide Profiles in Patients with DIC and Related Diseases (2011)
  • Author(s): Habe K, Wada H, Ito-Habe N, Hatada T, Matsumoto T, Ohishi K, Maruyama K, Imai H, Mizutani H, Nobori T
  • Journal Title: Thromb Res. Volume: (Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Monitoring for anti-Xa activity for prophylactic administration of fondaparinux in patients with artificial joint replacement (2011)
  • Author(s): Yoshida K, Wada H, Hasegawa M, Wakabayashi H, Ando H, Oshima S, Matsumoto T, Shimokariya Y, Noma K, Yamada N, Uchida A, Nobori T, Sudo A
  • Journal Title: Int J Hematol Volume: 94 Pages: 355-360
  • NAID: 10030265323
  • Peer Reviewed
• [Journal Article] High Plasma Level of Factor VIII (2011)
  • Author(s): Ota S, Yamada N, Ogihara Y, Tsuji A, Ishikura K, Nakamura M, Wada H, Ito M
  • Journal Title: Circ J Volume: 75 Pages: 1472-1475
  • Peer Reviewed
• [Journal Article] Japanese Society of Thrombosis Hemostasis/DIC subcommittee. Prospective evaluation of hemostatic abnormalities in overt DIC due to various underlying diseases (2011)
  • Author(s): Kawasugi K, Wada H, Hatada T, Okamoto K, Uchiyama T, Kushimoto S, Seki Y, Okamura T, Nobori T
  • Journal Title: Thromb Res Volume: 128 Pages: 186-90
  • Peer Reviewed
• [Journal Article] Katayama N Elevated Von Willebrand factor propeptide for the diagnosis of thrombotic microangiopathy and for predicting a poor outcome (2011)
  • Author(s): Ito-Habe N, Wada H, Matsumoto T, Ohishi K, Toyoda H, Ishikawa E, Nomura S, Komada Y, Ito M, Nobori T
  • Journal Title: Int J Hematol Volume: 93 Pages: 47-52
  • Peer Reviewed
• [Journal Article] Prospective evaluation of three different diagnostic criteria for disseminated intravascular coagulation (2011)
  • Author(s): Takemitsu T, Wada H, Hatada T, Ohmori Y, Ishikura K, Takeda T, Sugiyama T, Yamada N, Maruyama K, Katayama N, Isaji S, Shimpo H, Kusunoki M, Nobori T
  • Journal Title: Thromb Haemost Volume: 105 Pages: 40-44
  • Peer Reviewed
• [Journal Article] Personalized treatment in the eradication therapy for Helic obacter pylori (2011)
  • Author(s): Jinda S, Wada H, et al
  • Journal Title: Int J Mol Med Volume: 27 Pages: 255-261
  • Peer Reviewed
• [Journal Article] Elevated Von Willebrand factor propeptide for the diagnosis of thrombotic microangiopathy and for predicting a poor outcome (2011)
  • Author(s): Ito-Habe N, Wada H, et al
  • Journal Title: Int J Hematol Volume: 93 Pages: 47-52
  • NAID: 10029532480
  • Peer Reviewed
• [Journal Article] Molecular diagnosis of nonaneurysmal infectious aortitis (2011)
  • Author(s): Kanemitsu S, Wada H, et al
  • Journal Title: J Vasc Surg Volume: 53 Pages: 472-474
  • Peer Reviewed
• [Journal Article] Prospective evaluation of hemostatic abnormalities in overt DIC due to various underlying diseases (2011)
  • Author(s): Kawasugi K, Wada H, et al
  • Journal Title: Thromb Res Volume: 128 Pages: 186-190
  • Peer Reviewed
• [Journal Article] Efficiency of diversion of the first aliquot of blood and prestorage leukoreduction for preventing bacterial contamination in red blood concentrates assessed using a rapid polymerase chain reaction-bas bacterial detection system (2011)
  • Author(s): Nakamura A, Wada H, et al
  • Journal Title: Transfus Med Volume: 21 Pages: 365-370
  • Peer Reviewed
• [Journal Article] Reply (2011)
  • Author(s): Kanemitsu S, Wada H, et al
  • Journal Title: J Vasc Surg Volume: 54 Pages: 1233-1234
  • Peer Reviewed
• [Journal Article] Neutrophil elastase affects not only tissue damage, but it also regulates hemotopoiesis (2011)
  • Author(s): Wada H, Habe K
  • Journal Title: Thromb Res Volume: 126 Pages: 205-206
  • Peer Reviewed
• [Journal Article] Japanese Society of Thrombosis Hemostasis/DIC subcommittee.: Modified non-overt DIC diagnostic criteria predict the early phase of overt-DIC (2010)
  • Author(s): Wada H, Hatada T, Okamoto K, Uchiyama T, Kawasugi K, Mayumi T, Gando S, Kushimoto S, Seki Y, Madoiwa S, Okamura T, Toh CH
  • Journal Title: Am J Hematol Volume: 85 Pages: 691-694
  • Peer Reviewed
• [Journal Article] The association of protein S Tokushima-K196E with a risk of deep vein thrombosis (2010)
  • Author(s): Ikejiri M, Wada H, Sakamoto Y, Ito N, Nishioka J, Nakatani K, Tsuji A, Yamada N, Nakamura M, Ito M, Nobori T
  • Journal Title: Int J Hematol Volume: 92 Pages: 302-305
  • NAID: 10026712289
  • Peer Reviewed
• [Journal Article] A second national questionnaire survey of TMA (2010)
  • Author(s): Ito-Habe N, Wada H, Matsumoto M, Fujimura Y, Murata M, Izuno T, Sugita M, Ikeda Y
  • Journal Title: Int J Hematol Volume: 92 Pages: 68-75
  • NAID: 10026512028
  • Peer Reviewed
• [Journal Article] Prevention of venous thromboembolism according to the guidelines of a domestic manual (2010)
  • Author(s): Kaneko T, Wada H, Nobori T, Yamada N, Nakamura M, Ito M
  • Journal Title: Int J Hematol Volume: 91 Pages: 909-911
  • NAID: 10026511545
  • Peer Reviewed
• [Journal Article] Elevated Fibrin-Related Markers in Patients with Malignant Diseases Suspected of Having Thrombotic Disorders (2010)
  • Author(s): Nomura H, Wada H, Mizuno T, Yamashita Y, Saito K, Kitano S, Katayama N, Yamada N, Sugiyama T, Sudo A, Usui M, Isaji S, Nobori T
  • Journal Title: Clin Appl Thromb Hemost Volume: 16 Pages: 266-272
  • Peer Reviewed
• [Journal Article] Evaluation of modified non-overt DIC criteria on the prediction of poor outcome in patients with sepsis (2010)
  • Author(s): Oh D, Jang MJ, Lee SJ, Chong SY, Kang MS, Wada H
  • Journal Title: Thromb Res Volume: 126 Pages: 18-23
  • Peer Reviewed
• [Journal Article] Japanese Society of Thrombosis Hemostasis/DIC subcommittee : Frequency and hemostatic abnormalities in pre-DIC patients (2010)
  • Author(s): Okamoto K, Wada H, Hatada T, Uchiyama T, Kawasugi K, Mayumi T, Gando S, Kushimoto S, Seki Y, Madoiwa S, Asakura H, Koga S, Iba T, Maruyama I
  • Journal Title: Thromb Res Volume: 126 Pages: 74-78
  • Peer Reviewed
• [Journal Article] Analysis three abnormal Protein S genes in a patient with pulmonary embolism (2010)
  • Author(s): Ikejiri M, Tsuji A, Wada H, Sakamoto Y, Nishioka J, Ota S, Yamada N, Matsumoto T, Nakatani K, Nobori T, Itoh M
  • Journal Title: Thromb Res Volume: 125 Pages: 529-532
  • Peer Reviewed
• [Journal Article] Conventional therapy with an ACE inhibitor diminishes left ventricular dyssynchrony during the progression of heart failure. (2010)
  • Author(s): Kurita T, Wada H, et al
  • Journal Title: Int J Cardiol Volume: 140 Pages: 48-54
  • Peer Reviewed
• [Journal Article] Analysis three abnormal Protein S genes in a patient with pulmonary embolism. (2010)
  • Author(s): Ikejiri M, Wada H, et al
  • Journal Title: Thromb Res Volume: 125 Pages: 529-532
  • Peer Reviewed
• [Journal Article] Frequency and hemostatic abnormalities in pre-DIC patients. (2010)
  • Author(s): Wada H, et al
  • Journal Title: Thromb Res Volume: 126 Pages: 74-78
  • Peer Reviewed
• [Journal Article] Diagnostic Value of PCR Analysis of Bacteria and Fungus from Blood in Empiric Therapy-Resistant Febrile Neutropenia. (2010)
  • Author(s): Nakamura A, Wada H, et al
  • Journal Title: J Clin Microbiol Volume: 48 Pages: 2030-2036
  • Peer Reviewed
• [Journal Article] Evaluation of modified non-overt DIC criteria on the prediction of poor outcome in patients with sepsis. (2010)
  • Author(s): Oh D, Wada H, et al
  • Journal Title: Thromb Res Volume: 126 Pages: 18-23
  • Peer Reviewed
• [Journal Article] Group A streptococcal toxic shock syndrome with extremely aggressive course in the third trimester. (2010)
  • Author(s): Sugiyama T, Wada H, et al
  • Journal Title: J Obstet Gynaecol Res Volume: 36 Pages: 852-855
  • NAID: 10031121705
  • Peer Reviewed
• [Journal Article] Elevated Fibrin-Related Markers in Patients with Malignant Diseases Suspected of Having Thrombotic Disorders. (2010)
  • Author(s): Nomura H, Wada H, et al
  • Journal Title: Clin Appl Thromb Hemost Volume: 16 Pages: 266-272
  • Peer Reviewed
• [Journal Article] Prevention of venous thromboembolism according to the guide lines of a domestic manual. (2010)
  • Author(s): Kaneko T, Wada H, et al
  • Journal Title: Int J Hematol Volume: 91 Pages: 909-911
  • Peer Reviewed
• [Journal Article] Differential activation of eosinophils by 'probiotic' Bifidobacterium bifidum and 'pathogenic' Clostridium difficile (2010)
  • Author(s): Hosoki K, Wada H, et al
  • Journal Title: Int Arch Allergy Immunol Volume: 152 Pages: 83-89
  • Peer Reviewed
• [Journal Article] Modified non-overt DIC diagnostic criteria predict the early phase of overt-DIC (2010)
  • Author(s): Wada H, et al
  • Journal Title: Am J Hematol Volume: 85 Pages: 691-694
  • Peer Reviewed
• [Journal Article] National questionnaire survey of TMA (2009)
  • Author(s): Ito N, Wada H, Matsumoto M, Fujimura Y, Murata M, Izuno T, Sugita M, Ikeda Y
  • Journal Title: Int J Hemato Volume: 90 Pages: 328-335
  • NAID: 10026108869
  • Peer Reviewed
• [Journal Article] Decreased ADAMTS13 Levels in Patients after Living Donor Liver Transplantation (2009)
  • Author(s): Kobayashi T, Wada H, Usui M, Sakurai H, Matsumoto T, Nobori T, Katayama N, Uemoto S, Ishizashi H, Matsumoto M, Fujimura Y, Isaji S
  • Journal Title: Thromb Res Volume: 124 Pages: 541-5
  • Peer Reviewed
• [Journal Article] Cut-off values of D-dimer and soluble fibrin for prediction of deep vein thrombosis after orthopaedic surgery (2009)
  • Author(s): Sudo A, Wada H, Nobori T, Yamada N, Ito M, Niimi R, Hasegawa M, Suzuki K, Uchida A
  • Journal Title: Int J Hematol Volume: 89 Pages: 572-576
  • NAID: 10025161673
  • Peer Reviewed
• [Journal Article] Efficacy of procalcitonin in the early daignosis of bacterial infection in a critical care unit (2009)
  • Author(s): Nakamura A, Wada H, et al
  • Journal Title: Shock 31 Pages: 586-591
  • Peer Reviewed
• [Journal Article] Decreased ADAMTS13 Levels in Patients after Living Donor Liver Transplantation (2009)
  • Author(s): Kobayashi T, Wada H, et al
  • Journal Title: Thromb Res 124 Pages: 541-545
  • Peer Reviewed
• [Journal Article] National questionnaire survey of TMA (2009)
  • Author(s): Ito N, Wada H, et al
  • Journal Title: Int J Hematol 90 Pages: 328-335
  • NAID: 10026108869
  • Peer Reviewed
• [Journal Article] Molecular diagnosis of prosthetic valve endocarditis with aorto-right atrial fistula (2009)
  • Author(s): Takamura T, Wada H, et al
  • Journal Title: Int J Cardiol 135
  • Peer Reviewed
• [Journal Article] Usefulness of a diluted prothrombin time for accurately diagnosing antiphospholipid syndrome (2009)
  • Author(s): Nakai K, Wada H, et al
  • Journal Title: Vascular Disease Prevention 6 Pages: 25-29
  • Peer Reviewed
• [Journal Article] The Effectiveness of Measuring for Fragmented Red Cells Using an Automated Hematology Analyzer in Patients With Thrombotic Microangiopathy (2009)
  • Author(s): Abe Y, Wada H, et al
  • Journal Title: Clin Appl Thromb Hemost 15 Pages: 257-262
  • Peer Reviewed
• [Journal Article] PCR-Mediated early diagnosis of fungal infections in patients with living-donor liver transplantation transplants (2009)
  • Author(s): Nakamura A, Wada H, et al
  • Journal Title: The Open Infectious Diseases Journal 31 Pages: 73-79
  • Peer Reviewed
• [Journal Article] Cut-off values of D-dimer and soluble fibrin for prediction of deep vein thrombosis after orthopaedic surgery (2009)
  • Author(s): Sudo A, Wada H, et al
  • Journal Title: Int J Hematol 89 Pages: 572-576
  • NAID: 10025161673
  • Peer Reviewed
• [Journal Article] Mycotic Aortic Aneurysm Associated with Legionella anisa (2009)
  • Author(s): Tanabe M, Wada H, et al
  • Journal Title: J Clin Microbiol 47 Pages: 2340-2343
  • Peer Reviewed
• [Journal Article] Pregnancy-induced thrombocytopenia and TTP, and the risk of fetal death, in Upshaw-Schulman syndrome : a series of 15 pregnancies in 9 genotyped patients (2009)
  • Author(s): Fujimura Y, Wada H, et al
  • Journal Title: Br J Haematol 144 Pages: 742-745
  • Peer Reviewed
• [Journal Article] Neurotrophic receptor tyrosine kinase B induces c-fos-associated cell survival (2009)
  • Author(s): Hayashi A, Wada H, et al
  • Journal Title: Int J Mol Med 24 Pages: 807-811
  • Peer Reviewed
• [Journal Article] Elevated Fibrin-Related Markers in Patients with Malignant Diseases Suspected of Having Thrombotic Disorders (2009)
  • Author(s): Nomura H, Wada H, et al
  • Journal Title: Clin Appl Thromb Hemost. 2009 Epub Jul 31(Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Expert consensus for the treatment of disseminated intravascular coagulation in Japan (2009)
  • Author(s): Wada H, et al
  • Journal Title: Thromb Res Epub Sep 24(Epub ahead of print)
  • Peer Reviewed
• [Journal Article] Hemostatic abnormalities in the acute phase of trauma (2009)
  • Author(s): Wada H, et al
  • Journal Title: Thromb Res Epub Nov 13(Epub ahead of print)
  • Peer Reviewed
• [Presentation] Change of behavior in C4B binding protein and protein S in the patient with inflammatory disease (2011)
  • Author(s): Ikejiri M, Nishioka J, Sakamoto Y, Shimokariya Y, Noma K, Abe Y, Nakatani K, Wada H, Hayashi T, Suzuki K, Nobori T
  • Organizer: XXIIIth ISTH Congress
  • Place of Presentation: Kyoto
  • Year and Date: 2011-07-25
• [Presentation] Change of behavior in C4B binding protein and protein S in the patient with inflammatory disease (2011)
  • Author(s): Ikejiri M, Wada H, et al
  • Organizer: XXIIIth ISTH Congress
  • Place of Presentation: 京都国際会議場
  • Year and Date: 2011-07-25
• [Presentation] Quantitative analysis of the domain-specific autoantibodies to ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura (2011)
  • Author(s): Igari A, Moriki T, Yamaguchi Y, Nakagawa T, Wada H, Matsumoto M, Fujimura Y, Soejima K, Murata M
  • Organizer: The 53th Annual Meeting of The American Society of Hematology
  • Place of Presentation: San Diego
• [Presentation] 血栓・止血異常症診療センターの役割について (2011)
  • Author(s): 和田英夫
  • Organizer: 第21回日本臨床検査専門医会春季大会
  • Place of Presentation: 岩手アイーナ
• [Presentation] シンポジウム:血栓・止血異常症診療センターの役割について (2011)
  • Author(s): 和田英夫
  • Organizer: 第21回日本臨床検査専門医会春季大会
  • Place of Presentation: 岩手アイーナ
• [Presentation] PCR analysis of bacteria and fungi in early phase of hematopoietic stem cell transplantation (2011)
  • Author(s): Fujieda A, Wada H, et al
  • Organizer: The 53th Annual Meeting of The American Society of Hematology,
  • Place of Presentation: San Diego
• [Presentation] 静脈血栓塞栓症におけるフィブリン関連マーカーの有用性の検討 (2010)
  • Author(s): 和田英夫
  • Organizer: 第5回日本血栓止血学会学術標準化委員会シンポジウム(DIC部会)
  • Place of Presentation: 東医会館
  • Year and Date: 2010-10-30
• [Presentation] プロスペクティブスタデイの解析結果からのDIC診断における止血系マーカーの評価 (2010)
  • Author(s): 和田英夫
  • Organizer: 第5回日本血栓止血学会学術標準化委員会シンポジウム(DIC部会)
  • Place of Presentation: 東医会館
  • Year and Date: 2010-10-30
• [Presentation] プロスペクティブスタデイの解析結果からのDIC診断における止血系マーカーの評価 (2010)
  • Author(s): 和田英夫
  • Organizer: 第5回日本血栓止血学会学術標準化委員会シンポジウム
  • Place of Presentation: 東医会館(招待講演)
  • Year and Date: 2010-10-30
• [Presentation] 静脈血栓塞栓症におけるフィブリン関連マーカーの有用性の検討 (2010)
  • Author(s): 和田英夫
  • Organizer: 第5回日本血栓止血学会学術標準化委員会シンポジウム
  • Place of Presentation: 東医会館(招待講演)
  • Year and Date: 2010-10-30
• [Presentation] Chairperson's repot (2010)
  • Author(s): Wada H
  • Organizer: 57th SSC meeting subcommittee for DIC
  • Place of Presentation: Kyoto
  • Year and Date: 2010-07-24
• [Presentation] Chairman's report (2010)
  • Author(s): Wada H
  • Organizer: 56th SSC meeting subcommittee for DIC
  • Place of Presentation: Cairo
  • Year and Date: 2010-05-24
• [Presentation] the Japanese guideline on DIC treatment (2010)
  • Author(s): Wada H
  • Organizer: 56th SSC meeting subcommittee for DIC
  • Place of Presentation: Cairo
  • Year and Date: 2010-05-24
• [Presentation] the Japanese guideline on DIC treatment. (2010)
  • Author(s): Wada H
  • Organizer: 56^<th> SSC meeting subcommittee for DIC
  • Place of Presentation: Egypt Cairo(招待講演)
  • Year and Date: 2010-05-24
• [Presentation] 血栓症の臨床up-to-date、シンポジウムIII「血栓症高まる検査の役割」 (2010)
  • Author(s): 和田英夫
  • Organizer: 第42回日本臨床検査自動化学会
  • Place of Presentation: 神戸国際会議場
• [Presentation] DICの新しい概念と治療への展望～臨床検査部の立場から～、シンポジウム「DIC治療の新しい展開～リコモジュリン製剤の登場～」 (2010)
  • Author(s): 和田英夫
  • Organizer: 第11回日本検査血液学会学術集会
  • Place of Presentation: 東京ビッグサイト
• [Presentation] 日本血栓止血学会プロスペクティブスタディの解析報告、日本救急医学会ジョイントシンポジウム「DIC-診断と治療の最前線-」 (2010)
  • Author(s): 畑田剛、和田英夫
  • Organizer: 第33回日本血栓止血学会学術集会
  • Place of Presentation: 鹿児島
• [Presentation] Educational Lecture : Guidelines for management of DIC (2010)
  • Author(s): Wada H
  • Organizer: The 6^<th> Congress of Asia Pacific Society on Thrombosis and Haemostasis
  • Place of Presentation: Bali(招待講演)
• [Presentation] Lunch Symposium : Diagnostic guidelines for disseminated intravascular coagulation. The 6^<th> Congress of Asia Pacific Society on Thrombosis and haemostasis (2010)
  • Author(s): Wada H
  • Organizer: The 6^<th> Congress of Asia Pacific Society on Thrombosis and Haemostasis
  • Place of Presentation: Bali(招待講演)
• [Presentation] 教育講演:第三世代のフィブリン関連マーカー(SF)による血栓症の診断 (2010)
  • Author(s): 和田英夫
  • Organizer: 第33回日本血栓止血学会学術集会
  • Place of Presentation: 鹿児島(招待講演)
• [Presentation] 学術標準化委員会シンポジウム:静脈血栓塞栓症における二次的血栓性素因異常の検討のための臨床研究 (2010)
  • Author(s): 和田英夫, 他
  • Organizer: 第33回日本血栓止血学会学術集会
  • Place of Presentation: 鹿児島(招待講演)
• [Presentation] 日本救急医学会ジョイントシンポジウム:日本血栓止血学会プロスペクティブスタディの解析報告 (2010)
  • Author(s): 畑田剛、和田英夫
  • Organizer: 第33回日本血栓止血学会学術集会
  • Place of Presentation: 鹿児島(招待講演)
• [Presentation] DICの新しい概念と治療への展望～臨床検査部の立場から～ (2010)
  • Author(s): 和田英夫
  • Organizer: 第11回日本検査血液学会学術集会
  • Place of Presentation: 東京ビッグサイト(招待講演)
• [Presentation] 血栓症の臨床up-to-date (2010)
  • Author(s): 和田英夫
  • Organizer: 第42回日本臨床検査自動化学会
  • Place of Presentation: 神戸国際会議場(招待講演)
• [Presentation] A progress report on the prospective study for the diagnosis of DIC. (2009)
  • Author(s): Wada H, et al
  • Organizer: XXIIth ISTH Congress
  • Place of Presentation: Boston
  • Year and Date: 2009-07-13
• [Presentation] Evalution of non-overt DIC criteria (2009)
  • Author(s): Wada H
  • Organizer: 55^<th> SSC Annual meeting/XXIIth ISTH Congress
  • Place of Presentation: Boston
  • Year and Date: 2009-07-11
• [Book] 臨床病理レビュー 特集第147号 DIC-とびらを拓く第三世代へ-臨床病理刊行会 (2011)
  • Author(s): 尾崎由基男、和田英夫
• [Book] 臨床病理レビュー特集第147号DIC～とびらを拓く第三世代へ (2011)
  • Author(s): 尾崎由基男、和田英夫(監修)
  • Publisher: 臨床病理刊行会
• [Remarks]
  • URL: http://www.nedic.mic-u.ac.jp/th-center/