| Project/Area Number |
21590632
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
OBAYASHI Konen 熊本大学, 医学部附属病院, 講師 (90361899)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ANDO Yukio 熊本大学, 大学院・生命科学研究部, 教授 (20253742)
|
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
|---|
| Keywords | 膠原病 / シェーグレン症候群 / 後根神経節炎 / 自律神経ニューロパチー / ポリニューロパチー |
|---|
| Research Abstract |
In this study, we tried to develop early diagnostic markers of neuropathy with collagen disease and establish the clinical examination scheduling process. Our results suggest that quantitative sensory testing(QST), laser-Doppler flowmetry, and skin biopsy are the most useful methods to diagnose the neuropathy with collagen disease. Moreover, we could pick up many proteins and peptides which have the potential to become early diagnostic markers of the disease.
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