| Project/Area Number |
21590678
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
|
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| Research Institution | Hokkaido University |
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Principal Investigator |
SASAKI Seiko 北海道大学, 大学院・医学研究科, 助教 (30448831)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NAKAJIMA Sonomi 札幌医科大学, 保健医療学部, 講師 (70325877)
|
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| Co-Investigator(Renkei-kenkyūsha) |
KISHI Reiko 北海道大学, 環境健康科学研究教育センター, 特任教授 (80112449)
|
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 母子保健 / 遺伝的感受性素因 / 環境化学物質 / 小児神経発達 / 遺伝環境交互作用 |
|---|
| Research Abstract |
Genetic susceptibility to tobacco smoke might have relation to adverse birth outcomes. To estimate the effects of maternal smoking during pregnancy and genetic polymorphisms on infant neurodevelopment, we conducted a prospective birth cohort study of women who delivered singleton live births. Multiple linear regression models were used to estimate the association maternal smoking and certain polymorphisms with cognitive deficits at 6, 18 and 42 months of age. There was no correlation between any of the genotypes and adverse effects.
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