Study on discharged antimicrobials into aquatic environment and presence of antimicrobial-resistant organisms

• Project/Area Number: 21590684
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Nagasaki University
• Principal Investigator: OKUMURA Junko 長崎大学, 熱帯医学研究所, 准教授 (40323604)
• Co-Investigator(Kenkyū-buntansha): NAKAMURA Satoshi 国立国際医療センター, 熱帯医学・マラリア研究部, 室長 (40207874)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 薬剤耐性 / 抗生剤 / 環境水

Research Abstract

This study revealed the following four points. Firstly, the environment where we live has been polluted with antimicrobials and the concentrations were less than detection limit by LC-MS/ MS. Secondly, there was possibility that antimicrobials could not appropriately removed at water-treatment plants. Thirdly, the isolated gram-negative bacilli showed resistance to antimicrobials whose concentrations were undetectable by LC-MS/ MS. Fourthly, quite a few bacilli were not sensitive to Quinolones and Carbapenems, and these MDROs might threaten human health.

Research Products

• [Presentation] Presence of multidrug-resistant organisms in aquatic environment : What is its implication on human health (2011)
  • Author(s): Junko Okumura, Satoshi Nakamura, Taro Yamamoto
  • Organizer: IV International Conference on Medical Geology
  • Place of Presentation: Sheraton Nicolaus Hotel & Conference Centre in Bari, Italy
  • Year and Date: 2011-09-23
• [Presentation] Presence of multidrug-resistant organisms in aquatic environment : What is its implication on human health? (2011)
  • Author(s): Okumura, Junko
  • Organizer: IV International Conference on Medical Geology
  • Place of Presentation: Sheraton Nicolaus Hotel & Conference Centre in Bari, Italy
  • Year and Date: 2011-09-23
• [Presentation] インド洋大津波後の環境水中の耐性菌について(内容には本研究成果を含む) (2011)
  • Author(s): 奥村順子
  • Organizer: 第14回日本水環境学会シンポジウム「震災後の対応における水中病原微生物対策」
  • Place of Presentation: 仙台,東北工業大学
  • Year and Date: 2011-09-10
• [Presentation] シンポジウム「震災後の対応における水中病原微生物対策」:インド洋大津波後の環境水中の耐性菌について(内容には,本研究の成果を含む) (2011)
  • Author(s): 奥村順子
  • Organizer: 第14回日本水環境学会シンポジウム
  • Place of Presentation: 仙台,東北工業大学(シンポジスト)(招待)
  • Year and Date: 2011-09-10