The significance of central aortic blood pressure measurement for cardiovascular disease risk factors prevention in general population

• Project/Area Number: 21590691
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Osaka University
• Principal Investigator: CUI Renzhe 大阪大学, 医学系・研究科, 助教 (40375514)
• Co-Investigator(Kenkyū-buntansha): ISO Hiroyasu 大阪大学, 医学系・研究科, 教授 (50223053) ; OHIRA Tetsuya 大阪大学, 医学系・研究科, 准教授 (50448031) ; KITAMURA Akihiko 大阪府立健康科学センター, 健康開発部, 部長 (80450922)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 中心動脈圧 / 環器疾患 / リスクファクター / 疫学研究 / 循環器疾患 / 中心血圧 / AI / 循環器疾患リスクファクター

Research Abstract

We examined the associations of central aortic pressure, augmentation index(AI) and brachial blood pressure with ECG ST-T abnormalities and retinal changes in the general population. Men and women with high levels of central aortic pressure and AI had higher prevalence of ECG ST-T abnormalities and retinal changes. Central aortic pressure was strongly associated with ECG ST-T abnormalities than brachial blood pressure in elder men. The relationship between AI and ECG ST-T abnormalities was stronger in middle-aged men than in elder men.

Research Products

• [Journal Article] High serum total cholesterol levels is a risk factor of ischemic stroke for general Japanese population : The JPHC study (2012)
  • Author(s): Cui R, Iso H, et al
  • Journal Title: Atherosclerosis Volume: 221 Pages: 565-569
  • NAID: 120007130662
  • Peer Reviewed
• [Journal Article] Diabetes mellitus and risk of stroke and its subtypes among Japanese : the Japan public health center study (2011)
  • Author(s): Cui R, Iso H, Yamagishi K, Saito I, Kokubo Y, Inoue M, Tsugane S
  • Journal Title: Stroke Volume: 42 Pages: 2611-4
  • Peer Reviewed
• [Journal Article] CIRCS Investigators. Associations between alcohol consumption and sleep-disordered breathing among Japanese women (2011)
  • Author(s): Cui R, Tanigawa T, Sakurai S, Yamagishi K, Muraki I, Imano H, Ohira T, Kiyama M, Kitamura A, Ishikawa Y, Iso H
  • Journal Title: Respir Med Volume: 105 Pages: 796-800
  • Peer Reviewed
• [Journal Article] Diabetes mellitus and risk of stroke and its subtypes among Japanese : the Japan public health center study (2011)
  • Author(s): Cui R, Iso H, et al
  • Journal Title: Stroke Volume: 42 Pages: 2611-2614
  • Peer Reviewed
• [Journal Article] Epidemiology of metabolic syndrome in Japan : prevalence, sex difference and prognosis (2011)
  • Author(s): Iso H, Cui R, et al
  • Journal Title: Nihon Rinsho Volume: 69 Suppl Pages: 40-46
  • NAID: 40018269608
• [Journal Article] Associations between alcohol consumption and sleep-disordered breathing among Japanese women. (2011)
  • Author(s): Cui R, Tanigawa T, Sakurai S, et al.
  • Journal Title: Respir Med Volume: (In press)
  • Peer Reviewed
• [Journal Article] Tamakoshi A and JACC Study Group. Dietary folate, vitamin B_6 and B_12 intake in relation to mortality from cardiovascular disease : the Japan Collaborative Cohort Study Group (2010)
  • Author(s): Cui R, Iso H, Date C, Kikuchi S
  • Journal Title: Stroke Volume: 41 Pages: 1285-9
  • Peer Reviewed
• [Journal Article] Dietary folate, vitamin B_6 and B_<12> intake in relation to mortality from cardiovascular disease : the Japan Collaborative Cohort Study Group. (2010)
  • Author(s): Cui R, Iso H, Date C, et al.
  • Journal Title: Stroke Volume: 41 Pages: 1285-1289
  • Peer Reviewed
• [Journal Article] Pulse pressure is an independent risk factor for stroke among middle-aged Japanese with normal systolic blood pressure : the JPHC study. (2010)
  • Author(s): Okada K, Iso H, Cui R, et al.
  • Journal Title: J Hypertens Volume: 29 Pages: 319-324
  • Peer Reviewed
• [Journal Article] Associations between weight change since 20 years of age and sleep-disordered breathing among male truck drivers (2009)
  • Author(s): Cui R, Tanigawa T, Nakano H, SakuraiS, Yamagishi K, Ohira T, Iso H
  • Journal Title: Int J Obes Volume: 33 Pages: 1396-1401
  • Peer Reviewed
• [Journal Article] Relationship of Urinary cGMP Excretion with Aging and Menopausal Status in a General Population (2009)
  • Author(s): Cui R, Iso H, Yamagishi K, Ohira T, Tanigawa T, Kitamura A, Kiyama M, Imano H, Konishi M, Shimamoto T
  • Journal Title: J Atheroscler Thromb Volume: 16 Pages: 457-462
  • NAID: 10025766604
  • Peer Reviewed
• [Journal Article] Associations between weight change since 20 years of age and sleep-disordered breathing among male truck drivers (2009)
  • Author(s): Cui R, Tanigawa T, Nakano H, et al.
  • Journal Title: Int J Obes 33 Pages: 1396-1401
  • Peer Reviewed
• [Journal Article] Relationship of Urinary cGMP Excretion with Aging and Menopausal Status in a General Population (2009)
  • Author(s): Cui R, Iso H, Yamagishi K, et al.
  • Journal Title: J Atheroscler Thromb 16 Pages: 457-462
  • NAID: 10025766604
  • Peer Reviewed
• [Journal Article] C-reactive protein levels and risk of mortality from cardiovascular disease in Japanese : the JACC Study (2009)
  • Author(s): Iso H, Cui R, Date C, Kikuchi S, Tamakoshi A.
  • Journal Title: Atherosclerosis 207 Pages: 291-297
  • Peer Reviewed
• [Presentation] 地域住民における中心動脈圧・AI、上腕血圧と高血圧性臓器障害指標の関連 (2011)
  • Author(s): 崔仁哲, 他
  • Organizer: 第70回日本公衆衛生学会総会
  • Place of Presentation: 秋田市
  • Year and Date: 2011-10-20
• [Presentation] 地域住民における中心動脈圧と循環器疾患のリスクファクターとの関連 (2011)
  • Author(s): 崔仁哲、章文、李媛英, 他
  • Organizer: 第21回日本疫学会学術総会
  • Place of Presentation: 札幌 かでる2.7
  • Year and Date: 2011-01-22
• [Presentation] 地域住民における中心動脈圧・AI、上腕血圧と高血圧性臓器障害指標の関 (2011)
  • Author(s): 崔仁哲、章文、李媛英、木山昌彦、岡田武夫、北村明彦、山岸良匡、今野弘規、大平哲也、谷川武、石川善紀、磯博康
  • Organizer: 第70回日本公衆衛生学会総会日本公衆衛生学会総会
  • Place of Presentation: 秋田
• [Presentation] Associations between central aortic pressure and cardiovascular disease risk factors among general Japanese : the Circulatory Risk in Communities Study (2011)
  • Author(s): Cui R, Kitamura A, Kiyama M, Okada T, Maeda K, Yamagishi K, Imano H, Ohira T, Tanigawa T, Ishikawa Y, Iso H
  • Organizer: American Heart Association 51th Annual Conference on Cardiovascular Disease Epidemiology and Prevention
  • Place of Presentation: Atlanta, Georgia, USA
• [Presentation] 地域住民における中心動脈圧と循環器疾患のリスクファクターとの関連 (2011)
  • Author(s): 崔仁哲、章文、李媛英、北村明彦、木山昌彦、岡田武夫、前田健次、山岸良匡、今野弘規、大平哲也、谷川武、石川善紀、磯博康
  • Organizer: 第21回日本疫学学術総会
  • Place of Presentation: 札幌
• [Presentation] 地域住民における中心動脈圧・AIと循環器疾患リスクファクターとの関連 (2010)
  • Author(s): 崔仁哲、北村明彦、木山昌彦、岡田武夫、梅沢光政、清水悠路、前田健次、井戸正利、中村正和、石川善紀、今野弘規、大平哲也、磯博康
  • Organizer: 第10回臨床血圧脈波研究会
  • Place of Presentation: 東京
  • Year and Date: 2010-05-23
• [Presentation] 地域女性における飲酒習慣と睡眠呼吸障害、いびき、日中の眠気との関連 (2009)
  • Author(s): 崔仁哲, 谷川武, 桜井進, 他
  • Organizer: 第68回日本公衆衛生学学術総会
  • Place of Presentation: 奈良
  • Year and Date: 2009-10-21
• [Presentation] Associations between weight change and sleep-disordered breathing as well as excessive daytime sleepiness among male truck drivers (2009)
  • Author(s): Cui R, Tanigawa T, Sakurai S, Yamagishi K, Ohira T, Iso H
  • Organizer: American Heart Association 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention
  • Place of Presentation: Tampa, FL, USA
  • Year and Date: 2009-03-11