| Project/Area Number |
21590715
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
|
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
|
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| Co-Investigator(Kenkyū-buntansha) |
MIYAKOSHI Yuichi 東京慈恵会医科大学, 医学部, 講師 (00343533)
KOBAYASHI Koh 東京慈恵会医科大学, 医学部, 講師 (20118631)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 保健栄養 / 亜鉛 / 老化 / 酸化ストイレス / 発癌 / 血圧 / 酸化ストレス |
|---|
| Research Abstract |
It has been recently indicated that essential trace elements, particularly zinc deficiency is associated with aging. There are an increase in free radicals, an increase in blood pressure, a reduction in glucose tolerance, the disorder of lipid metabolism and a rise in carcinogenesis in the pathophysiological background of aging. Similar pathophysiology was also observed in zinc deficiency. Thus, the present study indicated that the latent national disease, Zn-deficiency was one of the aging-promoting factors.
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