Potential mechanisms responsible for aging promotion derived from the latent national disease, Zn-deficiency
| Project/Area Number |
21590715
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MIYAKOSHI Yuichi 東京慈恵会医科大学, 医学部, 講師 (00343533)
KOBAYASHI Koh 東京慈恵会医科大学, 医学部, 講師 (20118631)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 保健栄養 / 亜鉛 / 老化 / 酸化ストイレス / 発癌 / 血圧 / 酸化ストレス |
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| Research Abstract |
It has been recently indicated that essential trace elements, particularly zinc deficiency is associated with aging. There are an increase in free radicals, an increase in blood pressure, a reduction in glucose tolerance, the disorder of lipid metabolism and a rise in carcinogenesis in the pathophysiological background of aging. Similar pathophysiology was also observed in zinc deficiency. Thus, the present study indicated that the latent national disease, Zn-deficiency was one of the aging-promoting factors.
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Report
(4 results)
Research Products
(68 results)
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[Journal Article]2011
Author(s)
柳澤裕之
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Journal Title
平成22年度化学物質による健康影響・疾病に関する調査研究報告書
Pages: 1-110
Related Report
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[Journal Article] Klotho expression is induced by calorie restriction in adult male rats2010
Author(s)
T. Miyazaki, T. Takenaka, T. Inoue, M. Sato, M. Hanyu, Y. Eiki, M. Nodera, H. Yanagisawa, Y. Ohno, S. Shibasaki, H. Suzuki
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Journal Title
Trace Nutrients Res
Volume: 27
Pages: 92-96
Related Report
Peer Reviewed
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