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Primary Infection with Helicobacter pylori in Japanese Kindergarten Children

Research Project

Project/Area Number 21590720
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionTHE NIPPON DENTAL UNIVERSITY COLLEGE AT NIIGATA

Principal Investigator

SHIBASAKI Koichi  日本歯科大学新潟短期大学, 学長 (30018882)

Co-Investigator(Kenkyū-buntansha) WATANABE Takuya  日本歯科大学, 新潟生命歯学部, 准教授 (00440066)
HASEGAWA Katsuhiko  日本歯科大学, 新潟生命歯学部, 准教授 (60328870)
YAMAWAKI Toshihiro  日本歯科大学, 新潟生命歯学部, 助教 (00508492)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords感染症 / ピロリ菌(H. pylori) / 口腔衛生 / 幼児 / ピロリ菌(H.pylori)
Research Abstract

For the purpose of estimating the timing of primary infections by H. pylori, H. pylori DNA in saliva of kindergartners and their parent was detected. An infection rate of H. pylori tended to go up with age, and was significantly different between 4-and 5-years-old. Furthermore, H. pylori-positivity rates for the mothers of children who were H. pylori-positive were significantly higher than the mothers of H. pylori-negative children. These findings support the notion that primary infection occurs in children under 3 years of age, and the risk of H. pylori infection may be high in the children at 4-5 years. In addition, the fact that rates of H. pylori positivity are high in the mothers of H. pylori-positive children suggests that infection to a child from a mother is the most important factor.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (6 results)

All 2012 2010

All Presentation (6 results)

  • [Presentation] Primary Infection with Helicobacter pylori in Japanese Kindergarten Children2012

    • Author(s)
      上田潤、五十嵐隆一、山口晃、佐野公人、永合徹也、柴崎浩一
    • Organizer
      日中歯科医学大会
    • Place of Presentation
      中国成都
    • Year and Date
      2012-04-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Primary Infection with Helicobacter pylori in Japanese Kindergarten Children2012

    • Author(s)
      上田潤, 五十嵐隆一, 山口晃, 廣安一彦, 佐野公人, 永合徹也, 柴崎浩一
    • Organizer
      日中歯科医学大会2012
    • Place of Presentation
      中国成都
    • Year and Date
      2012-04-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Primary Infection with Helicobacter pylori in Japanese Kindergarten Children2010

    • Author(s)
      J. Ueda、R. Ikarashi、T. Kitagawa、A. Yamaguchi、K. Shibasaki
    • Organizer
      88^<Th> General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona、Spain
    • Year and Date
      2010-07-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Primary Infection with Helicobacter Pylori in Japanese Kindergarten Children2010

    • Author(s)
      J.Ueda, R.Ikarashi, T.Kitagawa, A.Yamaguchi, K.Shibasaki
    • Organizer
      88^<th> General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 幼稚園児を用いたヘリコバクター・ピロリ初感染時期に関する研究2010

    • Author(s)
      上田潤、五十嵐隆一、北川哲太郎、山口晃、柴崎浩一
    • Organizer
      第64回日本口腔科学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 幼稚園児の唾液を用いたヘリコバクター・ピロリ初感染時期に関する研究2010

    • Author(s)
      上田潤, 五十嵐隆一, 北川哲太郎, 山口晃, 柴崎浩一
    • Organizer
      第64回日本口腔科学会学術集会
    • Place of Presentation
      札幌プリンスホテル
    • Year and Date
      2010-06-24
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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