| Project/Area Number |
21590725
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Hokkaido Institute of Public Health |
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Principal Investigator |
ISHIDA Setsuko 北海道立衛生研究所, 感染症センター・感染症部, 主査(腸管系ウイルス) (70414315)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIZUMI Shima 北海道立衛生研究所, 感染症センター・感染症部, 研究職員 (90414317)
MIYOSHI Masahiro 北海道立衛生研究所, 感染症センター・感染症部, 主査(ウイルス感染症) (50414321)
KUDO Shinichi 北海道立衛生研究所, 感染症センター・微生物部, 部長 (00414318)
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| Co-Investigator(Renkei-kenkyūsha) |
MATSUBAYASHI Keiji 北海道赤十字血液センター, 検査部, 検査三課長 (90533323)
GOTO Akiko 北海道立衛生研究所, 感染症センター・感染症部, 研究職員 (60414322)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 疫学 / E型肝炎ウイルス / 診断 / 分子疫学 / ウイルス検出 / 感染症 |
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| Research Abstract |
A TaqMan RT-PCR was developed to detect and classify genotypes of hepatitis E virus(HEV). Putative animal reservoirs and environmental samples were studied to investigate potential routes of transmission for indigenous HEV infection. HEV RNA was detected using RT-PCR. HEV strains derived from swine liver, environmental samples shared 93-100% sequence similarity with human HEV strains.
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