| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
This was a population-based longitudinal study. Surveillance of men and women for SCD incidence and risk factors was conducted from 1981 to 2005. The surveyed population was all men and women aged 30-84 years who lived in three rural communities and one urban community(census population about 60, 000) in Japan. In this study, 471 people with SCD were identified over 25 years. Age-adjusted and sex-adjusted incidence of SCD decreased from 1981-85 to 1991-95, and plateaued thereafter. Moreover, the incidence of SCD was so high that a man and age were high.
The incidence of SCD was ascertained by systematic surveillance, with 239 cases of SCD identified over this period. For each case of SCD, three control subjects were selected, matched by age, sex, examination year, follow-up time, and community. Hypertension, diabetes mellitus, smoking, major ST-T abnormalities, high amplitude R waves, and increased heart rate(. 77beat/ min) were all independently associated with a 1. 5 to 3. 2-fold increase in SCD risk, while no associations were observed for body mass index(BMI) and hypercholesterolemia.
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