Scientific evaluation of therapeutic effects and mechanism of alternative therapies using PET molecular imaging technique.

• Project/Area Number: 21590754
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General internal medicine (including Psychosomatic medicine)
• Research Institution: Tohoku University
• Principal Investigator: TASHIRO Manabu 東北大学, サイクロトロン・ラジオアイソトープセンター, 教授 (00333477)
• Co-Investigator(Renkei-kenkyūsha): SEKI Takashi 東北大学, 医学系研究科, 講師 (90372292) ; FUJIMOTO Toshihiko 東北大学, 高等教育開発推進センター, 准教授 (00229048) ; YANAI Kazuhiko 東北大学, 医学系研究科, 教授 (50192787)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: カイロプラクティック / ストレス / ヒスタミン / フルオロデオキシグルコース(FDG) / ポジトロン断層法(PET) / 代替医療 / 局所脳活動 / 鍼灸治療 / 代替療法 / 局所脳糖代謝

Research Abstract

Histamine release in the brain of healthy volunteers evaluated by PET and[11C] doxepin investigation did not show significant changes induced by psychological stress(calculation task). Brain glucose metabolism in the brain of men with neck and shoulder pain showed significant changes associated with relaxation induced by chiropractic treatment and by the presence of accompanying animals. Glucose metabolic change measurement with PET and[18] FDG seems to be useful for evaluation of alternative therapies.

Research Products

• [Journal Article] [11C] Doxepin binding to histamine H1 receptors in living human brain in association with attentive waking and circadian rhythm (2012)
  • Author(s): Shibuya K, Funaki Y, Hiraoka K, Yoshikawa T, Miyake M, Watanuki S, Shao H, Tashiro M, Yanai K
  • Journal Title: Frontiers in Systems Neuroscience Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Effects of presence of a familiar pet dog on regional cerebral activity in healthy volunteers : a positron emission tomography study (2012)
  • Author(s): Sugawara A, Masud MM, Yokoyama A, Mizutani W, Watanuki S, Yanai K, Itoh M, Tashiro M
  • Journal Title: Anthrozoos Volume: Vol.25 Pages: 25-34
  • Peer Reviewed
• [Journal Article] Regional cerebral metabolic changes in patients with neck pain following chiropractic spinal manipulation : [18F] FDG PET Analysis (2011)
  • Author(s): Ogura T, Tashiro M, Masud M, Watanuki S, Shibuya K, Yamaguchi K, Itoh M, Fukuda H, Yanai K
  • Journal Title: Altern Ther Health Med Volume: Vol.17 Pages: 12-14
  • Peer Reviewed
• [Journal Article] 心身の活動と健康生成に関するイメージング研究 (2011)
  • Author(s): 田代学
  • Journal Title: Isotope News Volume: Vol.685 Pages: 2-7
  • NAID: 10027990906
• [Journal Article] Regional cerebral metabolic changes in patients with neck pain following chiropractic spinal manipulation : [18F] FDG PET Analysis (2011)
  • Author(s): Ogura T, Tashiro M, Masud M, Watanuki S, Shibuya K, Yamaguchi K, Itoh M, Fukuda H, Yanai K
  • Journal Title: Altern Ther Health Med. Volume: 17(確認中) Pages: 12-17
  • Peer Reviewed
• [Journal Article] Neural basis of pleasant and unpleasant emotions induced by social reputation (2011)
  • Author(s): Ito, et al
  • Journal Title: Neuroreport Volume: 22 Issue: 14 Pages: 679-683
  • DOI: 10.1097/wnr.0b013e32834a20b8
  • Peer Reviewed
• [Journal Article] A modified method of 3D-SSP analysis for amyloid PET imaging using [^<11>C]BF-227 (2011)
  • Author(s): Kaneta T, Okamuia N, Minoshima S, Furukawa K, Tashiro M, Furumoto S, Iwata R, Fukuda H, Takahashi S, Yanai K, Kudo Y, Arai H
  • Journal Title: Ann Nucl Med. Volume: 25 Issue: 10 Pages: 643-649
  • DOI: 10.1007/s12149-011-0518-7
  • NAID: 10030233510
  • Peer Reviewed
• [Journal Article] Positron emission tomography evaluation of sedative properties of antihistamines (2011)
  • Author(s): Yanai K, et al
  • Journal Title: Expert Opin Drug Saf Volume: 10(4) Issue: 4 Pages: 613-622
  • DOI: 10.1517/14740338.2011.562889
  • Peer Reviewed
• [Journal Article] Brain histamine H1 receptor occupancy of loratadine measured by positron emission topography : comparison of H1 receptor occupancy and proportional impairment ratio (2011)
  • Author(s): Kubo N, Yanai K, et al
  • Journal Title: Hum Psychopharmacol Volume: 26(2) Issue: 2 Pages: 133-139
  • DOI: 10.1002/hup.1184
  • Peer Reviewed
• [Journal Article] Effects of presence of a familiar pet dog on regional cerebral activity in healthy volunteers : a positron emission tomography study (2011)
  • Author(s): Sugawara A, Masud MM, Yokoyama A, Mizutani W, Watanuki S, Yanai K, Itoh M, Tashiro M
  • Journal Title: Anthrozoos Volume: (未定)(印刷中)
  • Peer Reviewed
• [Journal Article] Application of Positron Emission Tomography(PET)in Physical Medicine (2010)
  • Author(s): Masud MM, Fujimoto T, Watanuki S, Miyake M, Itoh M, Tashiro M
  • Journal Title: Mymensingh Med J Volume: Vol.19 Pages: 110-115
  • Peer Reviewed
• [Journal Article] Brain activity following esophageal acid infusion using positron emission tomography (2010)
  • Author(s): Kobayashi S, Abe Y, Tashiro M, Koike T, Iijima K, Imatani A, Ohara S, Watanabe S, Fukudo S, Shimosegawa T
  • Journal Title: World J Gastroenterol Volume: Vol.16 Pages: 5481-5489
  • Peer Reviewed
• [Journal Article] Regional cerebral metabolic changes in patients with neck pain following chiropractic spinal manipulation : [18F]FDG PET Analysis (2010)
  • Author(s): Ogura T, Tashiro M, Masud M, Watanuki S, Shibuya K, Yamaguchi K, Itoh M, Fukuda H, Yanai K
  • Journal Title: Altem Ther Health Med Volume: (未定)(印刷中)
  • Peer Reviewed
• [Journal Article] In vivo detection of prion amyloid plaques using [(11)C]BF-227 PET (2010)
  • Author(s): Okamura N, Shiga Y, Furumoto S, Tashiro M, Tsuboi Y, Furukawa K, Yanai K, Iwata R, Arai H, Kudo Y, Itoyama Y, Doh-Ura K
  • Journal Title: Eur J Nucl Med Mol Imaging Volume: 37 Pages: 934-941
  • Peer Reviewed
• [Journal Article] Amyloid PET in mild cognitive impairment and Alzheimer's disease with BF-227 : comparis on to FDG-PET (2010)
  • Author(s): Furukawa K, Okamura N, Tashiro M, Waragai M, Furumoto S, Iwata R, Yanai K, Kudo Y, Arai H
  • Journal Title: J Neurol Volume: 257 Pages: 721-727
  • Peer Reviewed
• [Journal Article] Function of the shoulder muscles during arm elevation : an assessment using positron emission tomography (2010)
  • Author(s): Omi R, Sano H, Ohnuma M, Kishimoto KN, Watanuki S, Tashiro M, Itoi E
  • Journal Title: J Anat Volume: 216 Pages: 643-649
  • Peer Reviewed
• [Journal Article] Application of Positron Emission Tomography (PET) in Physical Medicine (2010)
  • Author(s): Masud MM, Fujimoto T, Watanuki S, Miyake M, Itoh M, Tashiro M
  • Journal Title: Mymensingh Med J Volume: 19 Pages: 110-115
  • Peer Reviewed
• [Journal Article] Next-day residual sedative effect after nighttime administration of an over-the-counter antihistamine sleep aid, diphenhydramine, measured by positron emission tomography (2010)
  • Author(s): Zhang D, Tashiro M, Shibuya K, Okamura N, Funaki Y, Yoshikawa T, Kato M, Yanai K
  • Journal Title: J Clin Psychopharmacol Volume: 30 Pages: 694-701
  • Peer Reviewed
• [Journal Article] Long-tem performance evaluation of positron emission tomography : analysis and proposal of a maintenance protocol for long-term utilization (2010)
  • Author(s): Watanuki S, Tashiro M, Miyake M, Ishikawa Y, Itoh M, Yanai K, Sakemi Y, Fukuda H, Ishii K
  • Journal Title: Ann Nucl Med Volume: 24 Pages: 461-468
  • Peer Reviewed
• [Journal Article] In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy] benzoxazole positron emission tomography in multiple system atrophy (2010)
  • Author(s): Kikuchi A, Takeda A, Okamura N, Tashiro M, Hasegawa T, Furumoto S, Kobayashi M, Sugeno N, Baba T, Miki Y, Mori F, Wakabayashi K, Funaki Y, Iwata R, Takahashi S, Fukuda H, Arai H, Kudo Y, Yanai K, Itoyama Y
  • Journal Title: Brain Volume: 133 Pages: 1772-1778
  • Peer Reviewed
• [Journal Article] Voxel-based analysis of amyloid positron emission tomography probe[11C]BF-227 uptake in mild cognitive impairment and Alzheimer's disease (2010)
  • Author(s): Shao H, Okamura N, Sugi K, Furumoto S, Furukawa K, Tashiro M, Iwata R, Matsuda H, Kudo Y, Arai H, Fukuda H, Yanai K
  • Journal Title: Dement Geriatr Cogn Disord Volume: 30 Pages: 101-111
  • Peer Reviewed
• [Journal Article] Brain activity following esophageal acid infusion using positron emission tomography (2010)
  • Author(s): Kobayashi S, Abe Y, Tashiro M, Koike T, Iijima K, Imatani A, Ohara S, Watanabe S, Fukudo S, Shimosegawa T
  • Journal Title: World J.Gastroenterol. Volume: 16 Pages: 5481-5489
  • Peer Reviewed
• [Journal Article] Neural correlates of forgiveness for moral transgressions involving deception (2010)
  • Author(s): Hayashi A, Abe N, Ueno A, Shigemune Y, Mori E, Tashiro M, Fujii T
  • Journal Title: Brain Res Volume: 1332 Pages: 90-99
  • Peer Reviewed
• [Journal Article] Right temporal-lobe contribution to the retrieval of family relationships in person identification (2010)
  • Author(s): Abe N, Fujii T, Ueno A, Shigemune Y, Suzuki M, Tashiro M, Mori E
  • Journal Title: Neurosci Lett Volume: 486 Pages: 10-13
  • Peer Reviewed
• [Journal Article] Effects of emotion and reward motivation on neural correlates of episodic memory encoding : a PET study (2010)
  • Author(s): Shigemune Y, Abe N, Suzuki M, Ueno A, Mori E, Tashiro M, Itoh M, Fujii T
  • Journal Title: Neurosci Res Volume: 67 Pages: 72-79
  • Peer Reviewed
• [Journal Article] Amyloid PET in mild cognitive impairment and Alzheimer's disease with BF-227 : comparison to FDG-PET. (2010)
  • Author(s): Furukawa K, Okamura N, Tashiro M, Waragai M, Furumoto S, Iwata R, Yanai K, Kudo Y, Arai H.
  • Journal Title: J Neurol. (未定, 印刷中)
  • Peer Reviewed
• [Journal Article] Function of the shoulder muscles during arm elevation : an assessment using positron emission tomography. (2010)
  • Author(s): Omi R, Sano H, Ohnuma M, Kishimoto KN, Watanuki S, Tashiro M, Itoi E.
  • Journal Title: Neurosci Res. (未定, 印刷中)
  • Peer Reviewed
• [Journal Article] In vivo detection of prion amyloid plaques using [(11)C]BF-227 PET. (2010)
  • Author(s): Okamura N, Shiga Y, Furumoto S, Tashiro M, Tsuboi Y, Furukawa K, Yanai K, Iwata R, Arai H, Kudo Y, Itoyama Y, Doh-Ura K.
  • Journal Title: Eur J Nucl Med Mol Imaging. (未定, 印刷中)
  • Peer Reviewed
• [Journal Article] Application of Positron Emission Tomography(PET)in Physical Medicine. (2010)
  • Author(s): Masud MM, Fujimoto T, Watanuki S, Miyake M, Itoh M, Tashiro M.
  • Journal Title: Mymensingh Med J. 19 Pages: 110-115
  • Peer Reviewed
• [Journal Article] Effects of emotion and reward motivation on neural correlates of episodic memory encoding : a PET study. (2010)
  • Author(s): Shigemune Y, Abe N, Suzuki M, Ueno A, Mori E, Tashiro M, Itoh M, Fujii T.
  • Journal Title: Neurosci Res. 67 Pages: 72-79
  • Peer Reviewed
• [Journal Article] (2010)
  • Author(s): Tashiro M., Fujimoto T, Okamura N, Iwata R, Yanai K.
  • Journal Title: Molecular and functional imaging for drug development and elucidation of disease mechanisms using positron emission tomography (PET). IN : Molecular Imaging for Integrated Medical Therapy and Drug Development(Ed. KUGE Yuji.)(Springer Japan) Pages: 222-234
• [Journal Article] Redistribution of whole-body Energy Metabolism by Exercise : A Positron Emission Tomography study (2009)
  • Author(s): Masud MM, Fujimoto T, Tashiro M, Miyake M, Watanuki S, Itoh M
  • Journal Title: Ann Nucl Med Volume: Vol.23 Pages: 81-88
  • NAID: 10025135408
  • Peer Reviewed
• [Journal Article] Impact of serotonin transporter gene polymorphism on brain activation by colorectal distention (2009)
  • Author(s): Fukudo S, Kanazawa M, Mizuno T, Hamaguchi T, Kano M, Watanabe S, Sagami Y, Shoji T, Endo Y, Hongo M, Itoyama Y, Yanai K, Tashiro M, Aoki M
  • Journal Title: Neuroimage Volume: Vol.47 Pages: 946-951
  • Peer Reviewed
• [Journal Article] Evaluation of individual skeletal muscle activity by glucose uptake during pedaling exercise at different workloads using positron emission tomography (2009)
  • Author(s): Gondoh Y, Tashiro M, Itoh M, Masud MM, Sensui H, Watanuki S, Ishii K, Takekura H, Nagatomi R, Fujimoto T
  • Journal Title: J Appl Physiol Volume: Vol.107 Pages: 599-604
  • Peer Reviewed
• [Journal Article] Dose dependency of brain histamine H(1)receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with[11C] doxepin (2009)
  • Author(s): Tashiro M, Kato M, Miyake M, Watanuki S, Funaki Y, Ishikawa Y, Iwata R, Yanai K
  • Journal Title: Hum Psychopharmacol Volume: Vol.24 Pages: 540-548
  • Peer Reviewed
• [Journal Article] Dose dependency of brain histamine H1 receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [11C]doxepin. (2009)
  • Author(s): Tashiro M, Kato M, Miyake M, Watanuki S, Funaki Y, Ishikawa Y, Iwata R, Yanai K.
  • Journal Title: Human Psychopharmacology 24 Pages: 540-548
  • Peer Reviewed
• [Journal Article] Redistribution of whole-body energy metabolism by exercise : a positron emission tomography study. (2009)
  • Author(s): Masud MM, Fujimoto T, Miyake M, Watanuki S, Itoh M, Tashiro M.
  • Journal Title: Ann Nucl Med. 23 Pages: 81-88
  • NAID: 10025135408
  • Peer Reviewed
• [Journal Article] Decreased cortical glucose metabolism in converters from CDR 0.5 to Alzheimer's disease in a community : the Osaki-Tajiri Project. (2009)
  • Author(s): Ishii H, Ishikawa H, Meguro K, Tashiro M, Yamaguchi S.
  • Journal Title: Int Psychogeriatr. 21 Pages: 148-156
  • Peer Reviewed
• [Journal Article] Increased brain histamine H1receptor binding in patients with anorexia nervosa. (2009)
  • Author(s): Yoshizawa M, Tashiro M, Fukudo S, Yanai K, Utsumi A, Kano M, Karahasi M, Endo Y, Morisita J, Sato Y, Adachi M, Itoh M, Hongo M
  • Journal Title: Biol Psychiatry. 65 Pages: 329-335
  • Peer Reviewed
• [Journal Article] Comparison study of amyloid PET and voxel-based morphometry analysis in mild cognitive impairment and Alzheimer's disease. (2009)
  • Author(s): Waragai M, Okamura N, Furukawa K, Tashiro M, Furumoto S, Funaki Y, Kato M, Iwata R, Yanai K, Kudo Y, Arai H.
  • Journal Title: J Neurol Sci. 285 Pages: 100-108
  • Peer Reviewed
• [Journal Article] Differential diagnosis between radiation necrosis and glioma progression using sequential proton magnetic resonance spectroscopy and methionine positron emission tomography. (2009)
  • Author(s): Nakajima T, Kumabe T, Kanamori M, Saito R, Tashiro M, Watanabe M, Tominaga T.
  • Journal Title: Neurol Med Chir (Tokyo). 49 Pages: 394-401
  • NAID: 10025948513
  • Peer Reviewed
• [Journal Article] Evaluation of individual skeletal muscle activity by glucose uptake during pedaling exercise at different workloads using positron emission tomography. (2009)
  • Author(s): Gondoh Y, Tashiro M, Itoh M, Masud MM, Sensui H, Watanuki S, Ishii K, Takekura H, Nagatomi R, Fujimoto T.
  • Journal Title: J Appl Physiol. 107 Pages: 599-604
  • Peer Reviewed
• [Journal Article] Reactivation of medial temporal lobe and human V5/MT+ during the retrieval of motion information : a PET study. (2009)
  • Author(s): Ueno A, Abe N ; Suzuki M, Shigemune Y, Hirayama K, Mori E, Tashiro M, Itoh M, Fujii T.
  • Journal Title: Brain Res. 1285 Pages: 127-134
  • Peer Reviewed
• [Journal Article] Impact of serotonin transporter gene polymorphism on brain activation by colorectal distention. (2009)
  • Author(s): Fukudo S, Kanazawa M, Mizuno T, Hamaguchi T, Kano M, Watanabe S, Sagami Y, Shoji T, Endo Y, Hongo M, Itoyama Y, Yanai K, Tashiro M, Aoki M.
  • Journal Title: Neuroimage 47 Pages: 946-951
  • Peer Reviewed
• [Journal Article] Quantitative analysis of donepezil binding to acetylcholinesterase using positron emission tomography and [5-(11)C-methoxy]donepezil. (2009)
  • Author(s): Hiraoka K, Okamura N, Funaki Y, Watanuki S, Tashiro M, Kato M, Hayashi A, Hosokai Y, Yamasaki H, Fujii T, Mori E, Yanai K, Watabe H.
  • Journal Title: Neuroimage 46 Pages: 616-623
  • Peer Reviewed
• [Journal Article] Long-term performance evaluation of positron emission tomography-analysis and proposal of a maintenance protocol for long-term utilization. (2009)
  • Author(s): Watanuki S, Tashiro M, Miyake M, Ishikawa Y, Itoh M, Yanai K, Sakemi Y, Fukuda H, Ishii K.
  • Journal Title: Ann Nucl Med. 21 Pages: 148-156
  • NAID: 10026596410
  • Peer Reviewed
• [Journal Article] カイロプラクティック施術前後における腰椎の解剖学的位置関係の評価. (2009)
  • Author(s): 小倉毅、山口慶一郎、曽根理、田代学、伊藤正敏
  • Journal Title: 日本カイロプラクティック徒手医学会誌 10 Pages: 41-45
  • Peer Reviewed
• [Journal Article] 抗ヒスタミン薬と運転能力低下. (2009)
  • Author(s): 田代学, 谷内一彦
  • Journal Title: 日本医事新報 4446 Pages: 42-45
• [Journal Article] 抗ヒスタミン薬の鎮静作用評価に関するPET研究 (2009)
  • Author(s): 田代学, 谷内一彦.
  • Journal Title: 小児科 50 Pages: 1463-1476
  • NAID: 40016787949
• [Journal Article] 中枢に移行しない第二世代抗ヒスタミン薬:PETによる脳内移行性に関する研究. (2009)
  • Author(s): 谷内一彦, 田代学, 岡村信行.
  • Journal Title: 西日本皮膚科 71 Pages: 3-6
• [Journal Article] インペアード・パフォーマンス:国際標準に基づく抗ヒスタミン薬の使用法 (2009)
  • Author(s): 谷内一彦, 田代学
  • Journal Title: 医薬ジャーナル 45 Pages: 687-693
• [Journal Article] (2009)
  • Author(s): Tashiro M, Yanai K.
  • Journal Title: Potentials of nano-bio-imaging with positron emission tomography and radiopharmaceuticals. In : Nano-Biomedical Engineering 2009. IN : (Ed. YAMAGUCHI Takami)(Imperial College Press) Pages: 147-159
• [Journal Article] (2009)
  • Author(s): Yanai K., Okamura N, Iwata R, Tashiro M
  • Journal Title: Molecular imaging and its application to drug development at Tohoku University. In : Nano-Biomedical Engineering 2009.(Ed. YAMAGUCHI Takami)(Imperial College Press) Pages: 175-183
• [Journal Article] (2009)
  • Author(s): Masud M, Fujimoto T, Tashiro M, Yamaguchi S.
  • Journal Title: Evaluation of exercise-induced organ energy metabolism using two analytical approaches : A PET study. In : Nano-Biomedical Engineering 2009.(Ed. YAMAGUCHI Takami)(Imperial College Press) Pages: 195-200
• [Journal Article] (2009)
  • Author(s): Miyake, Yamamoto S, Itoh M, Kumagai K, Sasaki T, Santos TR, Tashiro M, Baba M.
  • Journal Title: Development of a new positron emission mammography (PEM). In : Nano-Biomedical Engineering 2009.(Ed. YAMAGUCHI Takami)(Imperial College Press) Pages: 201-206
• [Journal Article] The safety of newer antihistamines : Evaluation of their sedative properties by positron emission tomography
  • Author(s): Yanai K, Zhang D, Tashiro M, Shibuya K, Naganuma, Harada R, Nakamura T, Yoshikawa T, Okamura N
  • Journal Title: Expert Opinion on Drug Safety Volume: 2011(未定)(印刷中)
  • Peer Reviewed
• [Journal Article] Brain histamine H1 receptor occupancy of loratadine measured by PET : Comparison of H1 receptor occupancy and proportional impairment ratio
  • Author(s): Kubo N, Senda M, Osumi Y, Sakamoto S, Matsumoto K, Tashiro M, Okamura N, Yanai K
  • Journal Title: Human Psychopharmacol Volume: 2011(未定)(印刷中)
  • Peer Reviewed
• [Presentation] Neuroimaging evaluation of regional brain responses to alternative therapies : [18F] FDG PET studies (2012)
  • Author(s): Tashiro M, Ogura T, Sugawara A, Duan X, Masud M, Watanuki S, Itoh M, Yanai K
  • Organizer: European Conference of Radiology(ECR)
  • Place of Presentation: Vienna, Austria
• [Presentation] Neuroimaging evaluation of regional brain responses to alternative therapies : [^<18>F]FDG PET studies (2012)
  • Author(s): M.Tashiro, T.Ogura, A.Sugawara, X.Duan, M.M.Masud, S.Watanuki, M.Itoh, K.Yanai
  • Organizer: European Conference of Radiology (ECR)
  • Place of Presentation: Vienna, Austria
• [Presentation] 用手療法の有用性に関するFDG-PET研究 (2011)
  • Author(s): 小倉毅, 田代学, メヘディ・マスード, 四月朔日聖一, 平岡宏太良, 渋谷勝彦, 谷内一彦, 山口慶一郎, 伊藤正敏
  • Organizer: 日本核医学会学術総会
  • Place of Presentation: 茨城県つくば市
• [Presentation] 用手療法の有用性に関するFDG-PET研究 (2011)
  • Author(s): 小倉毅, 田代学, メヘディ・マスード, 四月朔日聖一, 平岡宏太良, 渋谷勝彦, 谷内一彦, 山口慶一郎, 伊藤正敏
  • Organizer: 日本核医学会学術総会
  • Place of Presentation: つくば市
• [Presentation] Recent interdisciplinary functional/molecular imaging studies at Tohoku University, Sendai, Japan (2010)
  • Author(s): Tashiro M
  • Organizer: Symposium 150 Jahre MVZ : Interdisciplinarity "Past-Present-future"
  • Place of Presentation: Oldenburg, Germany
  • Year and Date: 2010-09-18
• [Presentation] Measurement of histamine release change in living human brain associated with stress and circadian rhythm (2010)
  • Author(s): Shibuya K, Tashiro M, Watanuki S, Masud M, Miyake M, Kumagai K, Ishikawa Y, Iwata R, Yanai K
  • Organizer: 6th World Congress of Biomechanics and 14th International Conference on Biomedical Engineering
  • Place of Presentation: Singapore
• [Presentation] Scientific Evaluation on Effects of Chiropractic Treatment, a Type of Manual Therapy, using Magnetic Resonance Imaging(MRI)and Positron Emission Tomography(PET) (2010)
  • Author(s): Ogura T, Tashiro M, Masud M, Watanuki S, Shibuya K, Itoh M, Fukuda H, Yanai K
  • Organizer: 6th World Congress of Biomechanics and 14th International Conference on Biomedical Engineering
  • Place of Presentation: Singapore
• [Presentation] Quantitative Analysis of amyloid b deposition in the brain of Alzheimer's disease patients using PET with [11C]BF-227 and [18F]FACT (2010)
  • Author(s): Tashiro M, Okamura N, Furumoto S, Watanuki S, Kumagai K, Furukawa K, Funaki Y, Kimura Y, Iwata R, Kudo Y, Arai H, Watabe H, Yanai K
  • Organizer: World Congress on Biomechanics
  • Place of Presentation: Singapore, Singapore
• [Presentation] Pharmacokinetics of a new 18F-labeled amyloid imaging agent, [18F]FACT, in Alzheimer's disease patients (2010)
  • Author(s): Tashiro M, Okamura N, Watanuki S, Furumoto S, Furukawa K, Funaki Y, Iwata R, Kudo Y, Arai H, Yanai K
  • Organizer: World Molecular Imaging Conference 2010
  • Place of Presentation: Kyoto, Japan
• [Presentation] Pharmacokinetics of [18F]FACT, a new 18F-labeled amyloid imaging agent, in the brain Alzheimer's disease patients. Annual Meeting of EANM (2010)
  • Author(s): Tashiro M, Okamura N, Watanuki S, Furumoto S, Furukawa K, Funaki Y, Iwata R, Kudo Y, Arai H, Yanai K
  • Organizer: Annual Meeting of EANM
  • Place of Presentation: Vienna, Austria
• [Presentation] Quantitative Analysis of amyloid beta deposition in the brain of Alzheimer's disease patients using PET and [11C]BF-227 (2010)
  • Author(s): Tashiro M, Okamura N, Watanuki S, Furumoto S, Furukawa K, Funaki Y, Iwata R, Kudo Y, Arai H, Yanai K
  • Organizer: Annual Meeting of EANM
  • Place of Presentation: Vienna, Austria
• [Presentation] Functional and molecular imaging using positron emission tomography at Tohoku University : application to for health sciences. (2010)
  • Author(s): Tashiro M, Miyake M, Masud MM, Watanuki S, Okamura N, Yanai K, Fukuda H.
  • Organizer: SMART-Tohoku GCOE joint Workshop on Micro & Nano Bioengineering
  • Place of Presentation: Singapore, Singapore
• [Presentation] 心臓と筋肉の活動をみる:全身運動と健康. (2009)
  • Author(s): 田代学
  • Organizer: 第107回老年学公開講座
  • Place of Presentation: 東京
  • Year and Date: 2009-12-08
• [Presentation] 鍼灸治療による脳血流反応の観察 (2009)
  • Author(s): 田代学、関隆志、紺野亮、小林祐太、丸山将宏, 四月朔日聖一, 古川勝敏
  • Organizer: 日本統合医療学会
  • Place of Presentation: 東京
  • Year and Date: 2009-11-22
• [Presentation] 鍼灸治療による脳血流反応の観察 (2009)
  • Author(s): 紺野亮、田代学、関隆志、小林祐太
  • Organizer: 日本核医学会北日本地方会
  • Place of Presentation: 仙台市
  • Year and Date: 2009-10-20
• [Presentation] カイロプラクティック施術前後における腰椎の解剖学的位置関係の評価. (2009)
  • Author(s): 小倉毅、山口慶一郎、曽根理、田代学、伊藤正敏
  • Organizer: 日本カイロプラクティック徒手医学会誌
  • Place of Presentation: 東京
  • Year and Date: 2009-10-12
• [Presentation] 鍼灸治療による脳血流反応の観察 (2009)
  • Author(s): 田代学、関隆志、紺野亮、小林祐太
  • Organizer: 日本核医学会総会
  • Place of Presentation: 北海道旭川市
  • Year and Date: 2009-10-02
• [Presentation] Evaluation of cerebral activity and autonomic function in humans in vivo during accompanying with animal : a PET study (2009)
  • Author(s): Masud M, Sugawara A, Yokoyama A, Mizutani W, Watanuki S, Tashiro M, Itoh M
  • Organizer: 日本核医学会総会
  • Place of Presentation: 北海道旭川市
  • Year and Date: 2009-10-02
• [Presentation] 鍼灸治療による脳血流反応の観察 (2009)
  • Author(s): 田代学、関隆志、紺野亮、小林祐太
  • Organizer: 日本核医学会総会
  • Place of Presentation: 旭川市
  • Year and Date: 2009-10-02
• [Presentation] 心臓と筋肉の活動をみる:全身運動と健康. (2009)
  • Author(s): 田代学
  • Organizer: 第104回老年学公開講座
  • Place of Presentation: 東京
  • Year and Date: 2009-09-02
• [Presentation] Nano-bio-imaging with Radiopharmaceuticals and Application to Health Sciences. (2009)
  • Author(s): Tashiro M, Miyake M, Masud MM, Watanuki S.
  • Organizer: International Symposium on Global COE Program.
  • Place of Presentation: Sendai
  • Year and Date: 2009-03-28
• [Presentation] Human functional and molecular imaging using positron emission tomography(PET)for health promotion sciences (2009)
  • Author(s): Tashiro M, Masud MM, Jeong M, Fujimoto T, Miyake M, Watanuki S, Itoh M, Yanai K
  • Organizer: 3rd International Symposium of Nanomedicine(ISNM2009)
  • Place of Presentation: Okazaki, Aichi
• [Presentation] Human functional and molecular imaging using positron emission tomography(PET)for health promotion sciences. (2009)
  • Author(s): Tashiro M, Masud MM, Jeong M, Fujimoto T, Miyake M, Watanuki S, Itoh M, Yanai K.
  • Organizer: 3rd International Symposium of Nanomedicine (ISNM2009).
  • Place of Presentation: Okazaki
• [Presentation] Human functional imaging of skeletal muscles and brain during sports activity using positron emission tomography. (2009)
  • Author(s): Tashiro M, Masud MM, Jeong M, Fujimoto T, Miyake M, Watanuki S, Itoh M, Yanai K.
  • Organizer: Global COE Session, Annual Meeting of Asia-Pacific Association of Biomechanics.
  • Place of Presentation: Christchurch, Newzealand
• [Presentation] 抗ヒスタミン薬が自動車運転に与える深刻な影響. (2009)
  • Author(s): 田代学
  • Organizer: 日本交通科学協議会総会
  • Place of Presentation: 町田市
• [Book] PET Studies of Brain Metabolism in Exercise Research. IN : Functional Neuroimaging in Exercise and Sport Sciences (2012)
  • Author(s): Tashiro M, Fujimoto T, Masud MM, Khondkar S, Watanuki S, Yanai K, Itoh M, Ishii K
  • Publisher: Springer. New York, USA(印刷中)
• [Book] 頸部痛患者におけるカイロプラクティック施術後の局所脳代謝変化 (2011)
  • Author(s): 小倉毅、田代学、メヘディ・マスード、四月朔日聖一、渋谷勝彦、谷内一彦、山口慶一郎、伊藤正敏
  • Publisher: 日本カイロプラクティック徒手医学会
• [Book] Nano-bio-imaging with radiopharmaceuticals and its application to health sciences (2011)
  • Author(s): Tashiro M, Hiraoka K, Watanuki S, Masud MM, Miyake M, Kumagai K, Ogura T, Yanai K
  • Publisher: Research Publishing Services
• [Book] Quantitative Analysis of Amyloid β Deposition in Patients with Alzheimer's Disease Using Positr on Emission Tomography. IN : Early Detection and Rehabilitation Technologies for Dementia : Neuroscience and Biomedical Applications (2011)
  • Author(s): Tashiro M, Okamura N, Watanuki S, Furumoto S, Furukawa K, Funaki Y, Iwata R, Kudo Y, Arai H, Watabe H, Yanai K
  • Publisher: IGI Global. Philadelphia, USA
• [Book] PET Studies of Brain Metabolism in Exercise Research. IN : Functional Neuroimaging in Exercise and Sport Sciences (2011)
  • Author(s): Tashiro M, Fujimoto T, Masud MM, Khondkar S, Watanuki S, Yanai K, Itoh M, Ishii K
  • Publisher: Springer. New York, USA(印刷中)
• [Book] こころを画像で診る:その方法と患者心理研究への応用性.腎と透析.特集号「維持透析患者の補完代替医療ガイドブック」 (2011)
  • Author(s): 田代学、伊藤正敏
  • Publisher: 東京医学社(印刷中)
• [Book] Molecular and functional imaging for drug development and elucidation of disease mechanisms using positron emission tomography (PET) (2010)
  • Author(s): Tashiro M, Fujimoto T, Okamura N, Iwata R, Yanai K
  • Publisher: Springer Japan
• [Book] Molecular and functional imaging for drug development and elucidation of disease mechanisms. Molecular Imaging for Integrated Medical Therapy (2010)
  • Author(s): Tashiro M, Fujitmoto T, Okamura N, Iwata R, Yanai K
  • Publisher: Springer. New York, USA
• [Book] ヒスタミンH1受容体占拠率による脳内移行性評価.In:創薬技術の革新マイクロドーズからPET分子イメージングへの新展開 (2010)
  • Author(s): 谷内一彦、田代学、古本祥三、吉川雄朗、岡村信行
  • Publisher: メディカルドゥ社
• [Book] Quantitative Analysis of Amyloid β Deposition in Alzheimer's Disease Patients and Healthy Volunteers Using Positron Emission Tomography. In : Early Detection and Rehabilitation Technologies for Dementia : Neuroscience and Biomedical Applications (2010)
  • Author(s): Tashiro M, Okamura N, Watanuki S, Furumoto S, Furukawa K, Funaki Y, Iwata R, Kudo Y, Arai H, Watabe H, Yanai K.
  • Publisher: (株)複合医工学研究所(印刷中)
• [Book] [^<11>C]BF-227 study of patients with protein misfolding diseases. In : Early Detection and Rehabilitation Technologies for Dementia : Neuroscience and Biomedical Applications (2010)
  • Author(s): Okamura N, Furumoto S, Tashiro M, Furukawa K, Arai H, Doh-ura K, Kudo Y, Yanai K.
  • Publisher: (株)複合医工学研究所(印刷中)
• [Book] PET Studies of Brain Metabolism in Exercise Research
  • Author(s): Tashiro M, Fujimoto T, Masud MM, Khondkar S, Watanuki S, Yanai K, Itoh M, Ishii K
  • Publisher: Springer
• [Remarks]
  • URL: http://kakuigaku.cyric.tohoku.ac.jp/index.html