| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
In order to establish non-invasive monitoring methods for dementia therapy, we investigated electrophysiological markers for Alzheimer disease(AD). We found patients with AD show ; 1) Slowing and reduced rhythmicity in alpha wave, 2) reduced functional connectivity between bilateral hemispheres, and 3) enhanced auditory middle latency responses. These changes are expected to be useful for the therapeutic monitoring for AD as functional biomarkers.
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