Evaluation of Efficacy and Long-term Results of Catheter Ablation in Drug-refractory Atrial Fibrillation
| Project/Area Number |
21590891
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Circulatory organs internal medicine
|
|---|
| Research Institution | Shiga University of Medical Science |
|---|
Principal Investigator |
ITO Makoto 滋賀医科大学, 医学部, 准教授 (70159911)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ASHIHARA Takashi 滋賀医科大学, 医学部, 助教 (80396259)
ITOH Hideki 滋賀医科大学, 医学, 助教 (30402738)
OZAWA Tomoya 滋賀医科大学, 医学部, 助教 (20584395)
NAKAZAWA Yuko 滋賀医科大学, 医学部, 助教 (90564914)
YAO Takenori 滋賀医科大学, 医学部, 医員 (90402726)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 心房細動 / カテーテルアブレーション / 再発 / 評価法 / ホームモニタリング / 遺伝子 / カテーテル治療 |
|---|
| Research Abstract |
Treatment of atrial fibrillation(AF) is important arrhythmia for prevention of cerebral infarction and maintenance of QOL. AF is sometimes refractory to antiarrhythmic drugs. Radiofrequency catheter ablation(CA) is a curative method for such AF patients. However, evaluation of AF recurrence after CA is variable among institutions. We utilized home monitoring with patient's activating event ECG recorders(EvR), and compared EvR with conventional methods. EvR was very useful tool for detection of AF, especially asymptomatic AF. Conventional methods underestimated AF recurrence rate than EvR ECGs. Predictors of AF recurrence after CA of AF were AF type, underlying diseases, left atrial size, and CHADS2-VASc score. We conclude that CA for AF is more effective when performed early AF stage, during the periods with less load to the left atrium in low CHADS2-VASc score AF patients without structural heart disease. Risk control of AF is also important after CA in such patients.
|
Report
(4 results)
Research Products
(74 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Journal Article] A novel KCNH2 mutation as a modifier for short QT interval.2009
Author(s)
Itoh H, Sakaguchi T, Ashihara T, Ding G W, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Ito M, Matsuura H, Horie M
-
Journal Title
URLInternational Journal of Cardiology 137(1)
Pages: 83-85
Related Report
Peer Reviewed
-
-
[Journal Article] Dose-response effects of bepridil in patients with persistent atrial fibrillation monitored with transtelephonic electrocardiograms : a multicenter, randomized, placebo-controlled, double-blind study(J-BAF Study).2009
Author(s)
Yamashita T, Ogawa S, Sato T, Aizawa Y, Atarashi H, Fujiki A, Inoue H, Ito M, Katoh T, Kobayashi Y, Koretsune Y, Kumagai K, Niwano S, Okazaki O, Okumura K, Saku K, Tanabe T, Origasa H, J-BAF Investigators
-
Journal Title
Circulation Journal 73
Pages: 1020-1027
NAID
Related Report
Peer Reviewed
-
[Journal Article] Latent genetic backgrounds and molecular pathogenesis in drug-induced long QT syndrome.2009
Author(s)
Itoh H, Sakaguchi T, Ding WS, Watanabe E, Watanabe I, Nishio Y, Makiyama T, Ohno S, Akao M, Higashi Y, Zenda N, Kubota T, Mori C, Okajima K, Haruna T, Miyamoto A, Kawamura M, Ishida K, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Sugimoto Y, Ashihara T, Hayashi H, Ito M, Imoto K, Matsuura H, Horie M
-
Journal Title
Circulation Arrhythmia and Electrophysiology 2(5)
Pages: 511-523
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 12誘導心電図による予後研究2010
Author(s)
宮本証, 石田勝也, 林秀樹, 吉野知秀, 水澤有香, 杉本嘉久, 伊藤誠, Joel Q.Xue, 堀江稔
Organizer
第20回京滋奈良ハートリズム研究会
Place of Presentation
京都
Year and Date
2010-02-13
Related Report
-
-
-
-
-
-
-
-
-
-
[Presentation] Latent genetic backgrounds and molecular pathogenesis in acquired long QT syndrome with distinct arrhythmic triggers..2010
Author(s)
Itoh H, Oka Y, Ding WG, Sakaguchi T, Kimura H, Mizusawa Y, Miyamoto A, Wu J, Ohno S, Makiyama T, Ito M, Matsuura H, Horie M
Organizer
AHA Scientific Sessions 2010
Place of Presentation
Chicago Illinois U.S.A
Related Report
-
-
-
-
-
-
-
-
[Presentation] 多量の心嚢水貯留を認めた好酸球性心筋炎の一例2009
Author(s)
吉井理一郎, 伊藤英樹, 高山幸一郎, 山下寛人, 八尾武憲, 谷口晋, 中澤優子, 芦原貴司, 山本孝, 高島弘行, 藤井応理, 中江一郎, 林秀樹, 杉本喜久, 松本鉄也, 蔦本尚慶, 伊藤誠, 堀江稔
Organizer
第67回 滋賀県循環器疾患研究会
Place of Presentation
滋賀
Year and Date
2009-09-12
Related Report
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 冠動脈洞開口以上を合併した防湿回帰性頻拍にカテーテル・アブレーションを施行し根治しえた1例2009
Author(s)
伊藤英樹, 八尾武憲, 宮本証, 中澤優子, 城日加里, 水澤有香, 芦原貴司, 八木崇文, 横田良司, 杉本喜久, 伊藤誠, 堀江稔
Organizer
第21回 カテーテル・アブレーション委員会公開研究会
Place of Presentation
埼玉
Related Report
-
-
-
-
-
