• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of the mechanism and the tachycardia circuit of the atrial tachycardia originating from the atrioventricular annulus

Research Project

Project/Area Number 21590904
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionKumamoto University

Principal Investigator

YAMABE Hiroshige  熊本大学, 医学部附属病院, 特任教授 (20419641)

Co-Investigator(Renkei-kenkyūsha) OGAWA Hisao  熊本大学, 生命科学研究部, 教授 (50177135)
OKUMURA Ken  弘前大学, 医学研究科, 教授 (20185549)
Research Collaborator KOYAMA Junjiro  熊本大学, 医学部附属病院, 特任准教授
MORIHISA Kenji  熊本大学, 医学部附属病院, 特任助教
KANAZAWA Hisanori  熊本大学, 生命科学研究部, 大学院生
HOSHIYAMA Tadashi  熊本大学, 生命科学研究部, 大学院生
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords心房性頻拍 / 房室弁輪 / リエントリー / 房室結節
Research Abstract

The purpose of this study was to elucidate the mechanism and the anatomical tachycardia circuit of the verapamil-sensitive atrial tachycardia, originating from the atrioventricular node. Entrainment and single extrastimulation technique, and radiofrequency technique revealed that the mechanism of this atrial tachycardia was due to reentry, which involves the calcium-channel dependent tissue in the reentry circuit. The slow conduction area, which is consisted of the calcium-channel dependent tissue, was shown to be extended outside the Koch's triangle.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (28 results)

All 2012 2011 2010 2009 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (11 results) Book (2 results) Remarks (5 results)

  • [Journal Article]2012

    • Author(s)
      山部浩茂、奥村謙、森久健二、古山准二郎、金澤尚徳、星山禎、小川久雄
    • Journal Title

      Heart Rhythm

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of the Mechanisms Initiating Random Wave Propagation at the Onset of Atrial Fibrillation Using Non-Contact Mapping : Role of Complex Fractionated Electrogram Region.2011

    • Author(s)
      山部浩茂, 他
    • Journal Title

      Heart Rhythm.

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ogawa H.Improvement Effect on Endothelial Function in Patients with Congestive Heart Failure Treated with Cardiac Resynchronization Therapy.2011

    • Author(s)
      榎本耕二、山部浩茂, 他
    • Journal Title

      Journal of Cardiology

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2010

    • Author(s)
      山部浩茂、田中靖章、森久健二、上村孝史、榎本耕治、河野宏明、小川久雄
    • Journal Title

      Circ Arrhythm Electrophysiol

      Volume: 3巻 Pages: 54-62

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of the anatomical tachycardia circuit in verapamil-sensitive atrial tachycardia originating from the vicinity of the atrioventricular node.2010

    • Author(s)
      山部浩茂, 他
    • Journal Title

      Circ Arrhythm Electrophysiol.

      Volume: 3 Pages: 54-62

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Catheter ablation of multiple focal atrial tachycardias originating from the tricuspid annulus using non-contact mapping system.2010

    • Author(s)
      森久健二、山部浩茂, 他
    • Journal Title

      Journal of Cardiology Cases

      Volume: 2 Pages: 170-173

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radiofrequency energy induced ventricular fibrillation in a case of idiopathic premature ventricular contraction originating from the left ventricular papillary muscle.2010

    • Author(s)
      山部浩茂, 他
    • Journal Title

      Internal Medicine

      Volume: 49 Pages: 1863-1866

    • NAID

      130000336865

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple forms of atypical atrioventricular nodal reentrant tachycardia with different right- and left-sided retrograde slow pathways.2010

    • Author(s)
      山部浩茂, 他
    • Journal Title

      Journal of Cardiology Cases

      Volume: 2 Pages: 111-114

    • NAID

      120002599078

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of the anatomical tachycardia circuit in verapamil-sensitive atrial tachycardia originating from the vicinity of the atrioventricular node2010

    • Author(s)
      山部浩茂
    • Journal Title

      Circ Arrhythm Electrophysiol 3

      Pages: 54-62

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanisms of the maintenance of atrial fibrillation : role of the complex fractionated atrial electrogram assessed by noncontact mapping2009

    • Author(s)
      山部浩茂
    • Journal Title

      Heart Rhythm. 6

      Pages: 1120-1128

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Analysis of the Mechanisms of Verapamil-sensitive Atrial Tachycardia Originating from the Vicinity of the Atrioventricular Node : Demonstration of Manifest Entrainment2011

    • Author(s)
      山部浩茂、森久健二、古山准二郎、金澤尚徳、星山禎、小川久雄
    • Organizer
      第75回日本循環器学会総会・学術集会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-08-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Analysis of the Mechanisms of Verapamil-sensitive Atrial Tachycardia Originating from the Vicinity of the Atrioventricular Node : Demonstration of Manifest Entrainment2011

    • Author(s)
      山部浩茂
    • Organizer
      第75回日本循環器学会総会・学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-08-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Comparison between the Pericardial Fat Volume and Area of Complex Fractionated Atrial Electrograms Region in Patients with Paroxysmal Atrial Fibrillation2011

    • Author(s)
      榎本耕二、山部浩茂, 他
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Year and Date
      2011-03-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] The Analysis of Relation between Complex Fractionated Atrial Electrograms Region and Oxidative Stress Level in Patients with Atrial Fibrillation2011

    • Author(s)
      金澤尚徳、山部浩茂, 他
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Year and Date
      2011-03-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of the Mechanisms of Verapamil-sensitive Atrial Tachycardia Originating From the Vicinity of the Atrioventricular Node : Demonstration of Manifest Entrainment2011

    • Author(s)
      山部浩茂, 他
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Year and Date
      2011-03-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Shift in Tachycardia Origin in Verapamil-sensitive Focal Atrial Tachycardia Arising from the Atrioventricular Annulus : Its Relation to Tachycardia Cycle Length2011

    • Author(s)
      森久健二、山部浩茂, 他
    • Organizer
      第75回日本循環器学会総会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Year and Date
      2011-03-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Demonstration of Manifest Entrainment in Verapamil-sensitive Atrial Tachycardia Originating from the Vicinity of the Atrioventricular Node : Consideration into the Mechanism and Anatomy of Tachycardia Circuit2010

    • Author(s)
      山部浩茂, 他
    • Organizer
      2010 Scientific Sessions of the American Heart Association
    • Place of Presentation
      IL, Chicago, アメリカ合衆国
    • Year and Date
      2010-11-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Electrophysiologic Characteristics of the Focal Discharges Critical for the Initiation of Atrial Fibrillation and its Relation to the Complex Fractionated Electrogram Region : Three-dimensional Analysis Using Non-contact Mapping2010

    • Author(s)
      山部浩茂, 他
    • Organizer
      2010 Scientific Sessions of the American Heart Association
    • Place of Presentation
      IL, Chicago, アメリカ合衆国
    • Year and Date
      2010-11-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of the Relation between Oxidative Stress Level and Thrombotic Risk Stratified by CHADS_2 Score in Atrial Fibrillation2010

    • Author(s)
      上村孝史、山部浩茂, 他
    • Organizer
      2010 Scientific Sessions of the American Heart Association
    • Place of Presentation
      IL, Chicago, アメリカ合衆国
    • Year and Date
      2010-11-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Demonstration of Manifest Entrainment in Verapamil-sensitive Atrial Tachycardia Originating from the Vicinity of the Atrioventricular Node : Consideration into the Mechanism and Anatomy of Tachycardia Circuit2010

    • Author(s)
      山部浩茂、森久健二、榎本耕治、金澤尚徳、小川久雄
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      シカゴ、イリノイ州、米国
    • Year and Date
      2010-11-14
    • Related Report
      2011 Final Research Report
  • [Presentation] Analysis of the Mechanisms Initiating Random Wave Propagation at the Onset of Atrial Fibrillation Using Non-contact Mapping : Role of Complex Fractionated Electrogram Region2009

    • Author(s)
      山部浩茂
    • Organizer
      2009 Scientific Sessions of the American Heart Association
    • Place of Presentation
      米国フロリダ州オーランド
    • Year and Date
      2009-11-17
    • Related Report
      2009 Annual Research Report
  • [Book] 改訂版カテーテルアブレーション(V:治療の実際;疾患部位別アプローチ3.心房頻拍)2010

    • Author(s)
      山部浩茂
    • Total Pages
      11
    • Publisher
      メジカルビュー社
    • Related Report
      2010 Annual Research Report
  • [Book] 「改訂版カテーテルアブレーション」V.治療の実際;疾患部位別アプローチ3.心房頻拍2010

    • Author(s)
      山部浩茂
    • Total Pages
      11
    • Publisher
      メジカルレビュー社
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://circep.ahajournals.org/cgi/content/full/3/1/54

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://circep.ahajournals.org/cgi/content/full/3/1/2?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=yamabe&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://circ.ahajournals.org/cgi/content/meeting_abstract/122/21_MeetingAbstracts/A11377?maxtoshow=&hits=10&RESULTFORMAT=1&author2=yamabe+hiroshige&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://circep.ahajournals.org/cgi/content/full/3/1/54

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://circep.ahajournals.org/cgi/content/full/3/1/2?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=yamabe&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi