Impact of exercise therapy on regression of coronary atherosclerotic plaque
| Project/Area Number |
21590910
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Research Collaborator |
MIYAUCHI Katsumi 順天堂大学, 医学部, 先任准教授 (60200119)
SHIMADA Kazunori 順天堂大学, 医学部, 准教授 (60327814)
NISHITANI Miho 順天堂大学, 医学部, 助教 (60407301)
KOBA Shinji 昭和大学, 医学部, 講師 (20276546)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 急性冠症候群 / 血管内超音波 / 冠動脈プラーク / 血管リモデリング / 包括的心臓 / リハビリテーション / 身体活動量 / 急性心筋梗塞 / 包括的心臓リハビリテーション / 包括的リハビリテーション |
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| Research Abstract |
We investigated the effects of comprehensive cardiac rehabilitation (CR) on coronary plaque volume changes and vascular remodeling in patients after acute coronary syndrome (ACS). We enrolled 41 consecutive patients after ACS and patients were divided into the CR (16 patients) and the non-CR group (25 patients). Plaque volume and vascular remodeling were not significantly changed in the two groups during 6 months. However, percent change in plaque volume showed a significant negative correlation with daily physical activity. Intensive physical activity may result in coronary plaque regression in patients after ACS.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Effects of phase III cardiac rehabilitation on mortality and cardiovascular events in elderly patients with stable coronary artery disease2010
Author(s)
Onishi T, Shimada K, Sato H, Seki E, Watanabe Y, Sunayama S, Ohmura H, Masaki Y, Nishitani M, Fukao K, Kume A, Sumide T, Mokuno H, Naito H, Kawai S, Daida H.
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Journal Title
Circulation Journal 74(4)
Pages: 709-714
NAID
Related Report
Peer Reviewed
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[Journal Article] Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome : A multicenter randomized trial evaluated by volumetric intravascular ultrasound using pitavastat in versus atorvastatin(JAPAN-ACS[japan assessment of pitavastatin and atorvastatin in acute coronary syndrome]study)2009
Author(s)
Hiro T, Kimura T, Morimoto T, Miyauchi K, Nakagawa Y, Yamagishi M, Ozaki Y, Kimura K, Saito S, Yamaguchi T, Daida H, Matsuzaki M, JAPAN-ACS Investigators
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Journal Title
Journal of the American College of Cardiology 54(4)
Pages: 293-302
Related Report
Peer Reviewed
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