Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Research Abstract |
We clarified the causal relationship between the autonomic nervous activity and cardiac arrhythmias in heart failure. Increased sympathetic activity has important role of both the maintenance and occurrence of arrhythmias in heart failure, including atrial brady-tachycardia and prolongation of ventricular repolarization and its dispersion. After sympathetic denervation using sympathetic ganglion ablation on both sides(from second level to fourth levels of thoracic spinal cord) was applied, cardiac arrhythmias in heart failure were significantly reduced. Sympathetic denervation using stellate ganglia ablation may be useful for treatment of cardiac arrhythmias in heart failure.
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