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Low-energy shock wave therapy for chronic heart failure

Research Project

Project/Area Number 21590922
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionTohoku University

Principal Investigator

ITO Kenta  東北大学, 大学院・医学系研究科, 准教授 (50375086)

Co-Investigator(Kenkyū-buntansha) HIROAKI Shimokawa  東北大学, 大学院・医学系研究科, 教授 (00235681)
TAKEDA Morihiko  国際医療福祉大学, 病院, 准教授 (30375084)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords慢性心不全 / 低出力体外衝撃波治療 / 血管新生 / 循環器・高血圧 / 再生医療 / 虚血性心疾患
Research Abstract

We have studied the effects of low-energy shock wave (SW)therapy on chronic heart failure. Chronic heart failure was induced in Dahl salt sensitive rats by high (8%)NaCl feeding. Animals were randomly divided into SW-treated group or control group. SW therapy ameliorated the depression of cardiac function and reduced sudden death when treated in the early phase of heart failure. To clarify the optimal therapeutic condition, further studies are needed.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2012 2011 2010 Other

All Journal Article (5 results) (of which Peer Reviewed: 3 results) Presentation (11 results) Book (1 results) Remarks (4 results)

  • [Journal Article] Extracorporeal shock wave therapy for ischemic cardiovascular disorders2011

    • Author(s)
      Ito K, Fukumoto Y, Shimokawa H.
    • Journal Title

      Am J Cardiovasc Drugs

      Volume: 11 Pages: 295-302

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 狭心症に対する低出力体外衝撃波を用いた血管新生療法2011

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      日本医事新報

      Volume: 4549 Pages: 48-49

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 低出力体外衝撃波治療2011

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      臨床と研究

      Volume: 88 Pages: 69-73

    • NAID

      130004698649

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 体外衝撃波を用いた非侵襲性血管新生治療2010

    • Author(s)
      伊藤健太, 下川宏明
    • Journal Title

      日内学雑誌

      Volume: 99 Pages: 188-194

    • NAID

      10027509204

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 体外衝撃波を用いた非侵襲性血管新生治療2010

    • Author(s)
      伊藤健太、下川宏明
    • Journal Title

      日本内科学会雑誌

      Volume: 99 Pages: 188-194

    • NAID

      10027509204

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 虚血性心血管疾患に対する低出力体外衝撃波治療2012

    • Author(s)
      伊藤健太、伊藤愛剛、福本義弘、下川宏明
    • Organizer
      H23年度衝撃波シンポジウム
    • Place of Presentation
      柏
    • Related Report
      2011 Final Research Report
  • [Presentation] 虚血性心血管疾患に対する新しい非侵襲的血管新生療法:低出力体外衝撃波治療2011

    • Author(s)
      羽尾清貴
    • Organizer
      第59回日本心臓病学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-09-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲的血管新生療法2011

    • Author(s)
      伊藤健太
    • Organizer
      第20回日本心血管インターベンション治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲的血管新生療法2011

    • Author(s)
      伊藤愛剛
    • Organizer
      第17回日本心臓リハビリテーション学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 虚血性心血管疾患に対する新しい非侵襲的血管新生療法:低出力体外衝撃波治療2011

    • Author(s)
      羽尾清貴, 伊藤健太, 芹澤玄, 福本義弘, 佐藤成, 下川宏明
    • Organizer
      第59回日本心臓病学会学術集会
    • Place of Presentation
      神戸
    • Related Report
      2011 Final Research Report
  • [Presentation] Low-energy extracorporeal shock wave therapy as a new and non-invasive angiogenic strategy for cardiovascular diseases2011

    • Author(s)
      Ito K, Kikuchi Y, Ito Y, Tsuburaya R, Aizawa K, Hao K, Takahashi J, Takeda M, Nakayama M, Fukumoto Y, Yasuda S, Shimokawa H.
    • Organizer
      第75回日本循環器学会学術集会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲性血管新生療法2011

    • Author(s)
      伊藤健太、伊藤愛剛、菊地翼、羽尾清貴、円谷隆治、相澤健太郎、高橋潤、武田守彦、中山雅晴、松本泰治、高木祐介、福本義弘、安田聡、下川宏明
    • Organizer
      第20回日本心血管インターベンション治療学会学術集会
    • Place of Presentation
      大阪
    • Related Report
      2011 Final Research Report
  • [Presentation] 低出力体外衝撃波治療:心血管疾患に対する新しい非侵襲性血管新生療法2011

    • Author(s)
      伊藤愛剛, 伊藤健太, 菊地翼, 羽尾清貴, 円谷隆治, 相澤健太郎, 高橋潤, 武田守彦, 中山雅晴, 松本泰治, 高木祐介, 福本義弘, 安田聡, 下川宏明
    • Organizer
      第17回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      大阪
    • Related Report
      2011 Final Research Report
  • [Presentation] Non-invasive revascularisation by cardiac shock wave therapy in chronic ischemia : Animal and clinical studies.2010

    • Author(s)
      Kenta Ito
    • Organizer
      World Congress of Cardiology 2010
    • Place of Presentation
      Beijing, China
    • Year and Date
      2010-06-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Non-invasive revascularisation by cardiac shock wave therapy in chronic ischemia Animal and clinical studies2010

    • Author(s)
      Ito K
    • Organizer
      World Congress of Cardiology 2010
    • Place of Presentation
      Beijing, China
    • Related Report
      2011 Final Research Report
  • [Presentation] Extracorporeal shock wave therapy as a new and non-invasive angiogenic strategy2010

    • Author(s)
      伊藤健太
    • Organizer
      第74回日本循環器学会学術集会
    • Place of Presentation
      京都
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Book] 薬物治療無効、血行再建不適当患者に残された治療は何か?2012

    • Author(s)
      伊藤健太、下川宏明
    • Related Report
      2011 Final Research Report
  • [Remarks] 体外衝撃波治療のホームページ

    • URL

      http://www.cardio.med.tohoku.ac.jp/shockwave/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks] 体外衝撃波治療のHomepage

    • URL

      http://www.cardio.med.tohoku.ac.jp/shockwave/index.html

    • Related Report
      2011 Annual Research Report
  • [Remarks] 体外衝撃波治療のHomepage

    • URL

      http://www.cardio.med.tohoku.ac.jp/shockwave/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks] 体外衝撃波治療のHomepage

    • URL

      http://www.cardio.med.tohoku.ac.jp/shockwave/index.html

    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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