The evaluation of effect of anti-inflammatory drugs on chronic obstructive pulmonary disease with area-detector CT
| Project/Area Number |
21590966
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Kobe University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NISHIMURA Yoshihiro 神戸大学, 大学院・医学研究科, 准教授 (20291453)
FUNADA Yasuhiro 神戸大学, 医学部附属病院, 助教 (60437465)
KOBAYASHI Kazuyuki 神戸大学, 大学院・医学研究科, 特命講師 (50403275)
OHNO Yoshiharu 神戸大学, 大学院・医学研究科, 特命准教授 (30324924)
TAKENAKA Daisuke 神戸大学, 大学院・医学研究科, 准教授 (60258233)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 領域検出型CT / 閉塞性肺疾患 / 呼吸機能検査 / Area-detector CT / COPD / モストグラフ / 慢性閉塞性肺疾患 / ADCT / Bronchial asthma |
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| Research Abstract |
We compared the parameters of area-detector CT to that of respiratory function test to evaluate the obstructive respiratory disorder in COPD patients. The parameters of obstruction(% FEV1. 0, FEV1. 0%, RV,% RV) worsen in COPD patients with high frequency of resonance. The ratio of airway wall thickness to total diameter(T/D ratio) was higher in COPD patients with high frequency of resonance. There was negative correlation between R5-R20and airway internal diameter in6th branch and positive correlation between R5-R20and airway wall area.
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Report
(4 results)
Research Products
(8 results)
