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Cortical network is responsible for the acquisition of epileptic activity in pre-natal focal cortical dysplasia model

Research Project

Project/Area Number 21591114
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurology
Research InstitutionKyushu University

Principal Investigator

SHIGETO Hiroshi  九州大学, 大学病院, 講師 (50335965)

Co-Investigator(Renkei-kenkyūsha) SUZUKI Satoshi  九州大学, 大学院・医学研究院, 准教授 (90294917)
OKAMOTO Tsuyoshi  九州大学, 大学院・医学研究院, 准教授 (90432913)
TAKASE Kei-ichiro  九州大学, 大学院・医学研究院, 講師 (00467903)
KAMADA Takashi  九州大学, 大学病院, 学術研究員 (70614460)
UEHARA Taira  九州大学, 大学病院, 臨床助教 (30631585)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsてんかん / 皮質異形成 / ネットワーク / グルタミン酸受容体 / 脳波 / 臨床神経生理学 / フェーズロッキング解析
Research Abstract

Applying freeze lesioning in the bilateral frontoparietal lobes during the prenatal period, we developed a cortical dysplasia rat model that can show spontaneous temporal lobe seizures. Immunohistochemical examinations using semiquantitative densitometry revealed the glutamine hyper-excitability at dysplasic lesion accelerate the hippocampal excitability. Phase locking analysis between dysplasic lesion and hippocampus showed the increment of synchronization between these two structures before the start of hippocampal seizure. These findings suggest the excitability in hippocampus increases gradually via the network between cortical dysplasia and hippocampus.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (78 results)

All 2012 2011 2010 2009 Other

All Journal Article (24 results) (of which Peer Reviewed: 20 results) Presentation (49 results) Book (1 results) Remarks (4 results)

  • [Journal Article] 神経内科医としてのてんかん診療2011

    • Author(s)
      重藤寛史
    • Journal Title

      臨床神経

      Volume: 51 Pages: 661-668

    • NAID

      10031164049

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] てんかんの初期診療と最近のトピックス2011

    • Author(s)
      重藤寛史
    • Journal Title

      福岡医学雑誌

      Volume: 102 Pages: 195-202

    • NAID

      40018954519

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高齢初発非けいれん性全般てんかん重積状態の1例2011

    • Author(s)
      松山友美, 重藤寛史, 佐竹真理恵
    • Journal Title

      臨床神経

      Volume: 51 Pages: 43-46

    • NAID

      10027870484

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Peri-orbital electrodes as a supplemental recording for detection of ictal discharges in medial temporal lobe epilepsy2011

    • Author(s)
      Shigeto H, Sakata A, Morioka T, Takase K, Hagiwara K, Kamada T, Kanamori Y, Hashiguchi K, Tobimatsu S, Yamashita N, Kira J
    • Journal Title

      Neurology Asia

      Volume: 16

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Peri-orbital electrodes as a supplemental recording for detection of ictal discharges in medial temporal lobe epilepsy2011

    • Author(s)
      Shigeto H., et al
    • Journal Title

      Neurology Asia

      Volume: 16 Pages: 303-307

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 神経内科医としてのてんかん診療2011

    • Author(s)
      重藤寛史
    • Journal Title

      臨床神経学

      Volume: 51 Pages: 661-668

    • NAID

      10031164049

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hyperexcitability restricted to the lower limb motor system in a patient with stiff-leg syndrome2011

    • Author(s)
      Iwata T, Shigeto H, et al
    • Journal Title

      J Clin Neurosci

      Volume: 18 Pages: 1720-1722

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 成人てんかんの最新治療2011

    • Author(s)
      重藤寛史
    • Journal Title

      臨床神経学

      Volume: 51 Pages: 997-999

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A late-onset case of nonconvulsive status epilepticus of generalized epilepsy2011

    • Author(s)
      Matsuyama Y, Shigeto H, Satake M.
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 51 Pages: 43-46

    • NAID

      10027870484

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in humans2010

    • Author(s)
      Hagiwara K, Okamoto T, Shigeto H, Ogata K, Somehara Y, Matsushita T, Kira J, Tobimatsu S
    • Journal Title

      Neuroimage

      Volume: 51 Pages: 412-420

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Altered white matter fractional anisotropy and social impairment in children with autism spectrum disorder.2010

    • Author(s)
      Noriuchi M, Kikuchi Y, Yoshiura T, Kira R, Shigeto H, Hara T, Tobimatsu S, Kamio Y.
    • Journal Title

      Brain Res

      Volume: 1362 Pages: 141-149

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of anti-Hu antibody and anti-GluR epsilon2 antibody-positive paraneoplastic neurological syndrome presenting with limbic encephalitis and peripheral neuropathy2010

    • Author(s)
      Samejima S, Tateishi T, Arahata H, Shigeto H, Ohyagi Y, Kira J.
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 50 Pages: 462-472

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oscillatory gamma synchronization binds the primary and secondary so matosensory areas in humans.2010

    • Author(s)
      Hagiwara K, Okamoto T, Shigeto H, Ogata K, et_al.
    • Journal Title

      Neuroimage.

      Volume: 51 Pages: 412-20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] てんかんのビデオ脳波モニタ2010

    • Author(s)
      重藤寛史, 吉良潤一
    • Journal Title

      医学のあゆみ

      Volume: 232 Pages: 1050-1055

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in humans2010

    • Author(s)
      Hagiwara K, Okamoto T, Shigeto H, Ogata K, et al.
    • Journal Title

      Neuroimage 51

      Pages: 412-20

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] てんかんのビデオ脳波モニタ2010

    • Author(s)
      重藤寛史, 吉良潤一
    • Journal Title

      医学のあゆみ 232

      Pages: 1050-1055

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Temporal lobe epilepsy associated with'triple pathology' of hippocampal sxlerosis, focal cortical dysplasia and cavernoma in the ipsilateral frontal lobe2009

    • Author(s)
      Samura K, Morioka T, Hashiguchi K, Miyagi Y, Shigeto H, Sakata A, Tanaka S, Sasaki T
    • Journal Title

      Epilepsy & Seizure

      Volume: 2 Pages: 34-41

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of mediodorsal thalamic nucleus stimulation in a rat model of cortical seizure2009

    • Author(s)
      Takase K, Shigeto H, Kamada T, Ohyagi Y, Kira J
    • Journal Title

      Fukuoka Igaku Zasshi

      Volume: 100 Pages: 274-280

    • NAID

      120001672650

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cortical kindling in a focal freeze lesion rat model2009

    • Author(s)
      Takase K, Shigeto H, Suzuki SO, Kikuchi H, Ohyagi Y, Kira J
    • Journal Title

      J Clin Neurosci

      Volume: 16 Pages: 94-98

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of mediodorsal thalamic nucleus stimulation in a rat model of cortical seizure2009

    • Author(s)
      Takase K, Shigeto H, Kamada T, Ohyagi Y, Kira J.
    • Journal Title

      Fukuoka Igaku Zasshi. 100

      Pages: 274-80

    • NAID

      120001672650

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cortical kindling in a focal freeze lesion rat model2009

    • Author(s)
      Takase K, Shigeto H, Suzuki SO, Kikuchi H, Ohyagi Y, Kira J.
    • Journal Title

      J Clin Neurosci. 16

      Pages: 94-8

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Temporal lobe epilepsy associated with 'triple pathology' of hippocampal sxlerosis, focal cortical dysplasia and cavernoma in the ipsilateral frontal lobe2009

    • Author(s)
      Kazuhiro Samura, Takato Morioka, Kimiaki Hashiguchi, Yasushi Miyagi, Hiroshi Shigeto, et al.
    • Journal Title

      Epilepsy & Seizure 2

      Pages: 34-41

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] てんかんに対するルーチン検査としての脳磁図の有用性と限界2009

    • Author(s)
      重藤寛史, 飛松省三
    • Journal Title

      臨床脳波 51

      Pages: 626-631

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 脳波検査技師と診療従事者で支えるてんかんのビデオ脳波モニタリング検査2009

    • Author(s)
      酒田あゆみ, 森岡隆人, 重藤寛史, ら
    • Journal Title

      臨床脳波 51

      Pages: 185-192

    • Related Report
      2009 Annual Research Report
  • [Presentation] 自発てんかん発作を有する皮質異形成ラットモデルの組織学的検討2012

    • Author(s)
      重藤寛史ら
    • Organizer
      九州山口てんかん外科研究会
    • Place of Presentation
      福岡タカクラホテル
    • Year and Date
      2012-02-04
    • Related Report
      2011 Final Research Report
  • [Presentation] 自発てんかん発作を有する皮質異形成ラットモデルの組織学的検討2012

    • Author(s)
      重藤寛史, ら
    • Organizer
      九州山口てんかん外科研究会
    • Place of Presentation
      福岡
    • Year and Date
      2012-02-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] 側頭葉てんかん患者の側頭内側活動関連活動のマグネトメーターを用いた解析2011

    • Author(s)
      重藤寛史, ら
    • Organizer
      日本てんかん学会
    • Place of Presentation
      新潟
    • Year and Date
      2011-10-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 実験てんかん-臨床へのフィードバック2011

    • Author(s)
      重藤寛史
    • Organizer
      Kyushu Neuroscience Conference
    • Place of Presentation
      福岡都ホテル
    • Year and Date
      2011-09-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 自発てんかん発作を有する両側皮質異形成ラットモデルの作成とその免疫組織化学的検討2011

    • Author(s)
      鎌田崇嗣ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2011-05-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 自発てんかん発作を有する両側皮質異形成ラットモデルの作成とその免疫組織化学的検討2011

    • Author(s)
      鎌田崇嗣, 重藤寛史, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳磁図によるてんかん患者海馬関連活動の抽出2011

    • Author(s)
      重藤寛史, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] てんかん外科症例における脳磁図所見と治療成績2011

    • Author(s)
      金森祐治, 重藤寛史, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] てんかん治療の最前線2011

    • Author(s)
      重藤寛史
    • Organizer
      日本神経学会総会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 全般てんかんか部分てんかんか~新規抗てんかん薬の効果を含めて~2011

    • Author(s)
      金森祐治, 重藤寛史
    • Organizer
      第197回てんかん懇話会
    • Place of Presentation
      福岡
    • Year and Date
      2011-04-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新皮質てんかんにおけるMEG双極子と頭皮上・皮質記録脳波のてんかん原性域との関係:後方視的解析による評価2011

    • Author(s)
      橋口公章, 森岡隆人, 村上信哉, 金森祐治, 萩原綱一, 染原裕子, 重藤寛史, 天野敏之, 佐々木富男
    • Organizer
      九州山口てんかん外科研究会
    • Place of Presentation
      福岡高倉ホテル
    • Year and Date
      2011-02-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 発作起始部位が前頭葉, 側頭葉のいずれであるか判断に迷った難治性てんかんの一例2011

    • Author(s)
      金森祐治, 重藤寛史, 鎌田崇嗣, 高瀬敬一郎, 吉良潤一, 森岡隆人, 橋口公章, 酒田あゆみ, 萩原綱一, 飛松省三
    • Organizer
      九州山口てんかん外科研究会
    • Place of Presentation
      福岡高倉ホテル
    • Year and Date
      2011-02-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Occurrence of spontaneous seizure activity in a bilateral prenatal freeze-lesion rat model2010

    • Author(s)
      Kamada et al
    • Organizer
      American Epilepsy Society 64 rd annual meeting
    • Place of Presentation
      San Antonio USA
    • Year and Date
      2010-12-07
    • Related Report
      2011 Final Research Report
  • [Presentation] Occurrence of spontaneous seizure activity in a bilateral prenatal freeze-lesion rat model2010

    • Author(s)
      Takashi Kamada, Wei Sun, Kei-ichiro Takase, Hiroshi Shigeto, Jun-ichi Kira
    • Organizer
      Annual meeting of American Epilepsy Society
    • Place of Presentation
      San Antonio, USA
    • Year and Date
      2010-12-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳波にて周期性-側性てんかん波発射を呈した血管内リンパ腫の1例2010

    • Author(s)
      金森祐治, 重藤寛史, 仲池隆史, 宮脇恒太, 酒田あゆみ, 飛松省三
    • Organizer
      日本臨床神経生理学会学術大会
    • Place of Presentation
      Kobe international conference center
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳皮質異常のMEG2010

    • Author(s)
      重藤寛史
    • Organizer
      日本臨床神経生理学会学術大会
    • Place of Presentation
      Kobe international conference center
    • Year and Date
      2010-11-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Patients with posterior basal temporal lobe epileptic discharge revealed by MEG2010

    • Author(s)
      Hiroshi Shigeto, Masami Fujii, Takato Morioka, Koichi Hagiwara, Yuji Kanamori, etc
    • Organizer
      International Congress of Clinical Neurophysiolog y
    • Place of Presentation
      Kobe international conference center
    • Year and Date
      2010-10-31
    • Related Report
      2010 Annual Research Report
  • [Presentation] 最小ノルム法によるてんかん性脳磁界活動の解析-皮質脳波記録所見との比較2010

    • Author(s)
      金森祐治, 重藤寛史, 左村和宏, 橋口公章, 森岡隆人, 酒田あゆみ, 廣永成人, 飛松省三, 吉良潤一
    • Organizer
      日本てんかん学会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2010-10-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 両側皮質異形成ラットで認めた自発性てんかん性放電2010

    • Author(s)
      鎌田崇嗣ら
    • Organizer
      日本てんかん学会学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-10-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的局所皮質異形成の機序に対する組織学的検討2010

    • Author(s)
      高瀬敬一郎, 重藤寛史, 鎌田崇嗣, 吉良潤一
    • Organizer
      日本てんかん学会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2010-10-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新皮質てんかんにおけるMEG双極子と頭皮上・皮質記録脳波のてんかん原性域との関係:後方視的解析による評価2010

    • Author(s)
      橋口公章, 森岡隆人, 村上信哉, 金森祐治, 萩原綱一, 染原裕子, 重藤寛史, 天野敏之, 佐々木富男
    • Organizer
      日本てんかん学会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2010-10-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 両側皮質異形成ラットで認めた自発性てんかん性放電2010

    • Author(s)
      鎌田崇嗣, 孫威, 高瀬敬一郎, 重藤寛史, 吉良潤一
    • Organizer
      日本てんかん学会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2010-10-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高齢初発非けいれん性全般てんかん重積の1例2010

    • Author(s)
      松山友美, 重藤寛史, 佐竹真理恵
    • Organizer
      日本てんかん学会九州地方会
    • Place of Presentation
      久留米大学
    • Year and Date
      2010-06-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 独立成分分析と最小ノルム法を用いたてんかん性磁界活動の自動検出の試み2010

    • Author(s)
      重藤寛史, 廣永成人, 萩原綱一, 金森祐治, 橋口公章, 森岡隆人, 飛松省三, 吉良潤一
    • Organizer
      日本神経学会学術大会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 両側皮質異形成ラットモデルの自発性てんかん性放電の有無の検討2010

    • Author(s)
      鎌田崇嗣, 孫威, 高瀬敬一郎, 重藤寛史, 吉良潤一
    • Organizer
      日本神経学会学術大会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 両側皮質異形成ラットモデルの自発性てんかん性放電の有無の検討2010

    • Author(s)
      鎌田崇嗣ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2010-05-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 全般てんかんか部分てんかんか2010

    • Author(s)
      金森祐治, 重藤寛史
    • Organizer
      福岡てんかん懇話会
    • Place of Presentation
      国立九州医療センター
    • Year and Date
      2010-04-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] てんかんの正しい診療2010

    • Author(s)
      重藤寛史
    • Organizer
      日本神経学会九州地区生涯教育講演会
    • Place of Presentation
      福岡
    • Year and Date
      2010-03-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 両側皮質異形成ラットで誌めた自発性てんかん性放電2010

    • Author(s)
      鎌田崇嗣, 重藤寛史, ら
    • Organizer
      九州山口てんかん外科研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-02-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] てんかんに必要な知識1-42010

    • Author(s)
      重藤寛史
    • Organizer
      福岡臨床と脳波懇話懇話会
    • Place of Presentation
      福岡センタービル
    • Related Report
      2010 Annual Research Report
  • [Presentation] 複雑部分発作として加療され両側放線冠・脳梁膨大部に拡散低下所見を認めた低血糖脳症の一例2009

    • Author(s)
      山下力, 重藤寛史, ら
    • Organizer
      日本神経学会九州地方会
    • Place of Presentation
      熊本
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Prenatal freeze lesioning produces epileptogenic focal cortical dysplasia2009

    • Author(s)
      高瀬敬一郎, 重藤寛史, et al.
    • Organizer
      American Epilepsy Society annual meeting
    • Place of Presentation
      Boston
    • Year and Date
      2009-12-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Creutzfelt-Jakob病にて認められだ周期性鋭波複合の特徴2009

    • Author(s)
      金森祐治, 重藤寛史, ら
    • Organizer
      日本臨床神経生理学会
    • Place of Presentation
      北九州
    • Year and Date
      2009-11-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] 脳ドック・認知症ドックなどにおける電気生理2009

    • Author(s)
      重藤寛史
    • Organizer
      日本臨床神経生理学会技術講習会
    • Place of Presentation
      北九州
    • Year and Date
      2009-11-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] ラット胎生期に作製した局所皮質異形成モデルにおけるてんかん原性の検討2009

    • Author(s)
      高瀬敬一郎, 重藤寛史, ら
    • Organizer
      日本てんかん学会
    • Place of Presentation
      弘前
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] ラット皮質てんかんモデルにおける視床背内側核刺激の検討2009

    • Author(s)
      高瀬敬一郎, 重藤寛史, ら
    • Organizer
      日本てんかん学会
    • Place of Presentation
      弘前
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] Automated detection of epileptic discharges using independent component analysis and minimum-norm estimates2009

    • Author(s)
      重藤寛史, et al.
    • Organizer
      2nd biannual conference of the International Society for the Advancement of Clinical Magnetoencephalography
    • Place of Presentation
      ギリシャ アテネ
    • Year and Date
      2009-09-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] てんかんの新しい治療法2009

    • Author(s)
      重藤寛史
    • Organizer
      臨床神経生理研究会
    • Place of Presentation
      福岡
    • Year and Date
      2009-08-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 海馬周囲皮質に加えた直流電流がてんかん性放電閾値に及ぼす影響の検討2009

    • Author(s)
      鎌田崇嗣, 重藤寛史, ら
    • Organizer
      日本てんかん学会九州地方会
    • Place of Presentation
      久留米
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] Phase-locking value を用いた1次・2次体性感覚野の機能的連関の評価2009

    • Author(s)
      萩原綱一, 重藤寛史, ら
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      金沢
    • Year and Date
      2009-05-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 脳波で両半球に広く分布する棘の脳磁図解析2009

    • Author(s)
      重藤寛史
    • Organizer
      日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 海馬皮質周囲に加えた直流電流がてんかん性放電閾値に及ぼす影響の検討2009

    • Author(s)
      鎌田崇嗣, 重藤寛史, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 健常者及びMS患者における二次体性感覚野の誘発磁界反応の比較検討2009

    • Author(s)
      萩原綱一, 重藤寛史, ら
    • Organizer
      日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 新規抗てんかん薬使用症例の検討2009

    • Author(s)
      重藤寛史
    • Organizer
      てんかん懇話会
    • Place of Presentation
      福岡
    • Year and Date
      2009-04-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] APPLICATION OF MINIMUM NORM ESTIMATION TO THE ANALYSIS OF INTERICTAL EPILEPTIC DISCHARGES : COMPARING WITH RECORDING OF ELECTROCORTICOGRAM2009

    • Author(s)
      金森祐治, 重藤寛史, et al.
    • Organizer
      Asian and Oceanic congress of clinical neurophysiology
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-04-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Prenatal freeze lesioning produces epileptogenic focal cortical dysplasia2009

    • Author(s)
      Takase et al
    • Organizer
      American Epilepsy Society 63 rd annual meeting
    • Place of Presentation
      Boston USA
    • Related Report
      2011 Final Research Report
  • [Presentation] ラット胎生期に作製した局所皮質異形成モデルにおけるてんかん原性の検討(Juhn and Mary WADA奨励賞受賞講演)2009

    • Author(s)
      高瀬敬一郎ら
    • Organizer
      日本てんかん学会学術集会
    • Place of Presentation
      弘前
    • Related Report
      2011 Final Research Report
  • [Presentation] Phase-locking valueを用いた1次・2次体性感覚野の機能的連関の評価2009

    • Author(s)
      萩原綱一ら
    • Organizer
      日本生体磁気学会
    • Place of Presentation
      金沢
    • Related Report
      2011 Final Research Report
  • [Presentation] APPLICATION OF MINIMUM NORM ESTIMATION TO THE ANALYSIS OF INTERICTAL EPILEPTIC DISCHARGES : COMPARING WITH RECORDING OF ELECTROCORTICOGRAM2009

    • Author(s)
      Kanamori et al
    • Organizer
      Asian and Oceanic congress of clinical neurophysiology
    • Place of Presentation
      Seoul Korea
    • Related Report
      2011 Final Research Report
  • [Book] 別冊医学のあゆみてんかん治療Update-研究と臨床の最前線、てんかんのビデオ脳波モニタ2011

    • Author(s)
      重藤寛史, 吉良潤一
    • Total Pages
      154
    • Publisher
      医歯薬出版社
    • Related Report
      2011 Final Research Report
  • [Remarks] ホームページ

    • URL

      http://www.med.kyushu-u.ac.jp/neuro/

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neuro/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neuro/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kyushu-u.ac.jp/neuro/

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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