| Budget Amount *help |
¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2012: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2011: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2010: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2009: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
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| Research Abstract |
In normal subjects, QPS over M1 inhibited the somatosensory cortex. We compared the effects of quadripulse transracial magnetic stimulation (QPS) on the median nerve somatosensory evoked potential (SEP) between patients with benign myoclonus epilepsy (ME) and normal subjects. In ME patients, any QPSs over M1 induced LTP like effects on S1 with no LTD like effects, which may be explained by a lack of LTD like mechanisms in ME patients. Additionally, we studied the QPS effects upon the cortical function of the intractable epilepsy patients. As the results, QPS did not inhibit the cortical function. We should take care in applying some plasticity induction method in patients because the frequency dependency may be completely different from those of normal subjects in some disorders. Even though, the results indicated characteristic cortical function of the patients.
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