| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
In patients with fulminant diabetes, the blood glucose levels are generally difficult to control because their endogenous insulin secretion are depleted from the onset. A patient with fulminant type 1 diabetes shows excellent glycemic control with small amount of exogenous insulin injection. This rare case leads us to hypothesize that an unknown insulin-like hormone will exist in this patient's blood. To explore this hypothesis, we have performed preliminary experiments of protein-protein interaction using human recombinant insulin receptor, although the results were not expected.
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