| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
To see whether nicotinic acid exerts its anti-hyperlipidemic effect through SIRT1 activation, expression of possible target genes of SIRT1, ABCA1 and CYP7A, in nicotinic acid administrated rat liver was examined. No change of the genes with marked increase in NAD has been observed so far.
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