Impact of visceral fat and adiponectin on association between sleep apnea and cardiovascular diseases
| Project/Area Number |
21591177
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Endocrinology
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| Research Institution | Osaka University |
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Principal Investigator |
KISHIDA Ken 大阪大学, 医学系研究科, 寄附講座助教 (10437329)
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| Co-Investigator(Kenkyū-buntansha) |
FUNAHASHI Tohru 大阪大学, 医学系研究科, 寄附講座教授 (60243234)
KIHARA Shinji 大阪大学, 医学系研究科, 講師 (20332736)
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIDA Ryoko よしだ睡眠呼吸クリニック, 院長
YOKOI Hiroyoshi 小倉記念病院, 循環器科, 部長
YANAGI Koji 大阪中央病院, 循環器科, 部長
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 内分泌学 / 医療・福祉 / 循環器・高血圧 / 糖尿病 / メタボリックシンドローム |
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| Research Abstract |
The study demonstrated that 1) co-existence of sleep-disordered breathing/ sleep apnea and visceral fat accumulation is important of preventing cardiovascular diseases, and 2) dysregulation of adipocytokines and increased oxidative stress are important factors as these molecular mechanisms.
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Report
(4 results)
Research Products
(58 results)
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[Journal Article] Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus2010
Author(s)
Kashine S, Kishida K, Funahashi T, Nakagawa Y, Otuki M, Okita K, Iwahashi H, Kihara S, Nakamura T, Matsuzawa Y, Shimomura I.
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Journal Title
Metabolism
Volume: 59(5)
Pages: 690-6
Related Report
Peer Reviewed
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