Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Research Abstract |
We examined induction of apoptosis, cytotoxicity, and change of tight junction due to TNF-α and non-steroidal anti-inflammatory drugs in model of Influenza virus encephalopathy using with human umbilical vein vascular endothelial cell(HUVEC). We evaluated influence of TNF-α to tight junction of HUVEC by western blot for Claudin-5 and Occludin, and by measurement of trans-endothelial epithelium endodermis electric resistance(TER) for alteration of cell permeability.
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