| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
We demonstrated that perivascular inflammatory cell infiltration may be temporally and spatially associated with the development of experimental pulmonary hypertension. Specifically, we showed that these infiltrating inflammatory cells contributed to the disease formation via releasing inflammation-related cytokines, IL-6 and IL-17. Further investigation is required to elucidate the role of these cytokines in the development of a new animal model, mimicking human pulmonary arterial hypertension.
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