Development of diagnostic system for Allergy by living cell-SPR
| Project/Area Number |
21591432
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dermatology
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| Research Institution | Hiroshima University |
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Principal Investigator |
HIDE Michihiro 広島大学, 大学院・医歯薬学総合研究科, 教授 (50284188)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 表面プラズモン共鳴 / アレルギー / イメージング / バイオセンサー / ナノバイオ / 二次元 / 細胞内情報伝達 / 好塩基球 |
|---|
| Research Abstract |
In this study, we developed a surface plasmon resonance imaging(SPRI) sensor for accurate clinical diagnosis of allergy with small amount of blood. We could detect individual basophil activations in response to various kinds of allergens using this sensor. This system may be a useful tool for clinical diagnosis of type I allergy using a drop of patient blood.
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Report
(4 results)
Research Products
(37 results)
