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Research on pathophysiological heterogeneity of panic disorder

Research Project

Project/Area Number 21591483
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionMie University

Principal Investigator

TANII Hisashi  三重大学, 大学院・医学系研究科, 准教授 (40346200)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsパニック障害 / 前頭葉機能 / COMTVal158Met多型 / Trait marker / State marker / 遺伝子多型 / 人格検査 / 中間表現型
Research Abstract

Several lines of evidence suggest that genetic factors might influence vulnerability to panic disorder(PD). Recent studies indicate that pathophysiological heterogeneity may play distinct clinical characteristics. We herein compared healthy controls and individuals with PD in terms of several gene polymorphisms, the Revised NEO Personality Inventory(NEO PI-R) and State-Trait Anxiety Inventory(STAI) scores. In the healthy younger generation, higher anxiety sensitivity was observed in the female group. A gender difference in anxiety sensitivity was shown in the dopamine 2 receptor C957T polymorphism in the healthy controls. The comorbidity of PD with or without agoraphobia and depression indicated a gender difference in PD patients. In early-onset PD, the STAI-T score was high in the Met/Met group of the brain-derived neurotrophic factor(BDNF) Val66Met genotype whereas the STAI-T score of the Val/Val group tended to be higher in healthy controls.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (67 results)

All 2012 2011 2010 2009 Other

All Journal Article (49 results) (of which Peer Reviewed: 44 results) Presentation (13 results) Book (5 results)

  • [Journal Article] Meta-analysis of genome-wide association studies identifies multiple novel loci associated with rheumatoid arthritis in the Japanese population2012

    • Author(s)
      Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl E, Kurreman F, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen P, Padyukov L, Worthington J, Siminovitch K, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge R, Yamanaka H, Momohara S, Yamada R, Matsuda F, and Yamamoto K.
    • Journal Title

      Nature Genetics

      Volume: 44 Pages: 511-516

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Meta-analysis of genome-wide association studies identifies multiple novel loci associated with rheumatoid arthritis in the Japanese population2012

    • Author(s)
      Okada Y, Tanii H, et al
    • Journal Title

      Nature Genetics

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Source localization of posterior slow waves of youth by dipolemodeling2012

    • Author(s)
      Ohoyama K, Tanii H, et al
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combination therapy of zonisamide with aripiprazole on electroconvulsive-therapy- and benzodiazepine-resistant periodic catatonia2012

    • Author(s)
      Nakagawa M, Tanii H, et al
    • Journal Title

      J Neuropsychiatry Clin Neurosci

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lamotrigine-Induced neuroleptic malignant syndrome under risperidone treatment2012

    • Author(s)
      Motomura E, Tanii H, et al
    • Journal Title

      J Neuropsychiatry Clin Neurosci

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Increase in the user rate of child seats is clearly an important factor in the decreases in the rates of death and serious Injury2012

    • Author(s)
      noue K, Tanii H, et al
    • Journal Title

      Am J Forensic Med Pathol

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroleptic malignant syndrome induced by blonanserine2011

    • Author(s)
      Ohoyama K, Tanii H, Motomura E, Konishi Y, Nakagawa M, Matsumoto T, Shiroyama T, Okada M
    • Journal Title

      J Neuropsychiatry Clin Neurosci

      Volume: 23(1)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex2011

    • Author(s)
      Ohoyama K, Yamamura S, Hamaguchi T, Nakagawa M, Motomura E, Shiroyama T, Tanii H, Okada M.
    • Journal Title

      Eur J Pharmacol

      Volume: 653(1-3) Pages: 47-57

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association analysis of RGS2 variants with panic disorder in a Japanese population2011

    • Author(s)
      Otowa T, Shimada T, Kawamura Y, Sugaya N, Yoshida E, Inoue K, Yasuda S, Liu X, Minato T, Tochigi M, Umekage T, Kasai K, Tanii H, Okazaki Y, Kaiya H, Sasaki T
    • Journal Title

      Am J Med Genet B Neuropsychiatr Genet

      Volume: 156B(4) Pages: 430-434

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] An association analysis of Per2 with panic disorder in the Japanese population2011

    • Author(s)
      Otowa T, Tochigi M, Kawamura Y, Sugaya N, Yoshida E, Inoue K, Yasuda S, Umekage T, Ebisawa T, Tanii H, Kaiya H, Okazaki Y, Kato N, Sasaki T
    • Journal Title

      J Hum Genet

      Volume: 56(10) Pages: 748-750

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide CNV association study on panic disorder in a Japanese population2011

    • Author(s)
      Kawamura Y, Otowa T, Koike A, Sugaya N, Yoshida E, Yasuda S, Inoue K, Takei K, Konishi Y, Tanii H, Shimada T, Tochigi M, Kakiuchi C, Umekage T, Liu X, Nishida N, Tokunaga K, Kuwano R, Okazaki Y, Kaiya H, Sasaki T
    • Journal Title

      J Hum Genet

      Volume: 56(12) Pages: 852-856

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A genome-wide CNV association study on panic disorder in a Japanese population2011

    • Author(s)
      Kawamura Y, Tanii H, et al
    • Journal Title

      J Hum Genet

      Volume: 56 Pages: 852-856

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Discussion of preventive measures against the increase of suicide among males in Japan2011

    • Author(s)
      Inoue K, Tanii H, et al
    • Journal Title

      Am J Forensic Med Pathol

      Volume: 32 Pages: 19-20

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An association analysis of Per2 with panic disorder in the Japanese population2011

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      J Hum Genet

      Volume: 56 Pages: 748-750

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association analysis of RGS2 variants with panic disorder in a Japanese population2011

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      Am J Med Genet B Neuropsychiatr Genet

      Volume: 156B Pages: 430-434

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroleptic malignant syndrome induced by blonanserine2011

    • Author(s)
      Ohoyama K, Tanii H, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences

      Volume: 23(1)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroleptic malignant syndrome induced by blonanserine.2011

    • Author(s)
      Ohoyama K, Tanii H, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences

      Volume: 23(1)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] I ffect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex.2011

    • Author(s)
      Ohoyama K, Tanii H, et al
    • Journal Title

      Eur J Pharmacol

      Volume: 653(1-3) Pages: 47-57

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association analysis of RGS2 variants with panic disorder in a Japanese population.2011

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      Am J Med Genet

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Replication of a genome-wide association study of panic disorder in a Japanese population.2010

    • Author(s)
      Otowa T, Tanii H, Sugaya N, Yoshida E, Inoue K, Yasuda S, Shimada T, Kawamura Y, Tochigi M, Minato T, Umekage T, Miyagawa T, Nishida N, Tokunaga K, Okazaki Y, Kaiya H, Sasaki T.
    • Journal Title

      J Hum Genet

      Volume: 55(2) Pages: 91-96

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Psychotic-like experiences are associated with suicidal feelings and deliberate self-harm behaviors in adolescents aged 12-15 years2010

    • Author(s)
      Nishida A, Sasaki T, Nishimura Y, Tanii H, Hara N, Inoue K, Yamada T, Takami T, Shimodera S, Itokawa M, Asukai N, Okazaki Y
    • Journal Title

      Acta Psychiatrica Scandinavica

      Volume: 121(4) Pages: 301-307

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroleptic malignant syndrome following levomepromazine discontinuation2010

    • Author(s)
      Tanii H, Saka K, Inoue K, Okada M
    • Journal Title

      The Journal of Neuropsychiatry and Clinical Neurosciences

      Volume: 22(2)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Frontal lobe dysfunction in panic disorder: a comparison of multichannnel near-infrared spectroscopy in monozygotic twins discordant for panic disorder2010

    • Author(s)
      Tanii H, Nishimura Y, Inoue K, Hara N, Nishida A, Okada M, Imamura A, Kaiya H, Okazaki Y
    • Journal Title

      The Journal of Neuropsychiatry and Clinical Neurosciences

      Volume: 22(2)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A euroleptic malignant syndrome following levomepromazine discontinuation.2010

    • Author(s)
      Tanii H, Saka K, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences

      Volume: 22(2)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The increase in suicide as a cause of death in men aged 40 to 59 years in Japan : a comparison between 1958 and 1998.2010

    • Author(s)
      Inoue K, Tanii H, et al
    • Journal Title

      West Indian Med J

      Volume: 59(1) Pages: 115-116

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Replication of a genome-wide association study of panic disorder in a Japanese population2010

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      J Hum Genet

      Volume: 55(2) Pages: 91-96

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Frontal lobe dysfunction in panic disorder : a comparison of multi-channel near-infrared spectroscopy in monozygotic twins discordant for panic disorder.2010

    • Author(s)
      Tanii H, Nishimura Y, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences

      Volume: 22(2)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of total health measures in Mie Prefecture, Japan Mie.2010

    • Author(s)
      Inoue K, Tanii H, et al
    • Journal Title

      West Indian Med J

      Volume: 59(1) Pages: 117-117

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neuroleptic malignant syndrome induced by blonanserine2010

    • Author(s)
      Ohoyama K, Tanii H, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Replication of a genome-wide association study of panic disorder in a Japanese population2010

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      J Hum Genet (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Frontal lobe dysfunction in panic disorder : a comparison of multi-channnel near-infrared spectroscopy in monozygotic twins discordant for panic disorder2010

    • Author(s)
      Tanii H, Nishimura Y, et al
    • Journal Title

      J Neuropsychiatry Clinical Neurosciences (印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population2009

    • Author(s)
      Otowa T, Shimada T, Kawamura Y, Liu X, Inoue K, Sugaya N, Minato T, Nakagami R, Tochigi M, Umekage T, Kasai K, Kato N, Tanii H, Okazaki Y, Kaiya H, Sasaki T
    • Journal Title

      J Hum Genet

      Volume: 54(8) Pages: 437-439

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task: near infrared spectroscopy study2009

    • Author(s)
      Tanii H, Nishimura Y, Inoue K, Koshimizu H, Matsumoto R, Takami T, Hara N, Nishida A, Okada M, Kaiya H, Okazaki Y
    • Journal Title

      Neuroscience Letters

      Volume: 452 Pages: 63-67

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genome-wide association study of panic disorder in the Japanese population2009

    • Author(s)
      Otowa T, Yoshida E, Yasuda S, Sugaya N, Nishimura Y, Inoue K, Tochigi M, Umekage T, Miyagawa T, Nishida N, Tokunaga K, Tanii H, Sasaki T, Kaiya H, Okazaki Y
    • Journal Title

      J Hum Genet

      Volume: 54 Pages: 122-126

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Specific panic attack symptoms in panic disorder patients with putative genetic factor2009

    • Author(s)
      Nishimura Y, Tanii H, Hara N, Inoue K, Nishida A, Okada M, Kaiya H, Okazaki Y
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 63 Pages: 251-252

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between the prefrontal function during a cognitive task and the severity of the symptoms in patients with panic disorder: a multi-channel NIRS study2009

    • Author(s)
      Nishimura Y, Tanii H, Hara N, Inoue K, Kaiya H, Nishida A, Okada M, Okazaki Y
    • Journal Title

      Psychiatry Research - Neuroimaging

      Volume: 172(2) Pages: 168-172

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin2009

    • Author(s)
      Yamamura S, Hamaguchi T, Ohoyama K, Sugiura Y, Suzuki D, Kanehara S, Nakagawa M, Motomura E, Matsumoto T, Tanii H, Shiroyama T, Okada M
    • Journal Title

      Epilepsy Res

      Volume: 84(2-3) Pages: 172-186

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intrasubject reproducibility of prefrontal cortex activities during averbal fluency task over two repeated sessions using multi-channelnear-infrared spectroscopy2009

    • Author(s)
      Kakimoto Y, Nishimura Y, Hara N, Okada M, Tanii H, Okazaki Y
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 63(4) Pages: 491-499

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex2009

    • Author(s)
      Yamamura S, Ohoyama K, Hamaguchi T, Nakagawa M, Suzuki D, Matsumoto T, Motomura E, Tanii H, Shiroyama T, Okada M
    • Journal Title

      Br J Pharmcol

      Volume: 157(4) Pages: 656-665

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intrasubject reproducibility of prefrontal cortex activities during averbal fluency task over two repeated sessions using multi-channelnear-infrared spectroscopy2009

    • Author(s)
      Kakimoto Y, Tanii H, et al
    • Journal Title

      Psychiatry and Clinical Neurosciences 63

      Pages: 491-499

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population2009

    • Author(s)
      Otowa T, Tanii H, et al
    • Journal Title

      J Hum Genet 54

      Pages: 437-439

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task : near infrared spectroscopy study2009

    • Author(s)
      Tanii H, Nishimura Y, et al
    • Journal Title

      Neuroscience Letters 452

      Pages: 63-67

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between the prefrontal function during a cognitive task and the severity of the symptoms in patients with panic disorder : a multi-channel LAIRS study2009

    • Author(s)
      Nishimura Y, Tanii H, et al
    • Journal Title

      Psychiatry Research-Neuroimaging 172

      Pages: 168-172

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Specific panic attack symptoms in panic disorder patients with putative genetic factor2009

    • Author(s)
      Nishimura Y, Tanii H, et al
    • Journal Title

      Psychiatry and Clinical Neurosciences 63

      Pages: 251-252

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      西村幸香, 谷井久志, 他
    • Journal Title

      精神疾患とNIRS第3章精神疾患への応用7.パニック障害・社会不安障害(中山書店)

      Pages: 144-153

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Lamotrigine-Induced neuroleptic malignant syndrome under risperidone treatment

    • Author(s)
      Motomura E, Tanii H, Usami A, Ohoyama K, Nakagawa M, Okada M
    • Journal Title

      J Neuropsychiatry Clin Neurosci

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] Combination therapy of zonisamide with aripiprazole on electroconvulsive-therapy- and benzo -diazepine - resistant periodic catatonia

    • Author(s)
      Nakagawa M, Yamamura S, Motomura E, Shiroyama T, Tanii H, Okada M
    • Journal Title

      J Neuropsychiatry Clin Neurosci

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] Source localization of posterior slow waves of youth by dipole modeling

    • Author(s)
      Ohoyama K, Motomura E, Inui K, Nishimura Y, Ushiro K, Matsushima N, Maeda M, Tanii H, Suzuki D, Hamanaka K, Kakigi R, Okada M
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] Levetiracetam inhibits neurotransmitter release associated with CICR

    • Author(s)
      Fukuyama K, Tanahashi S, Nakagawa M, Yamamura S, Motomura E, Shiroyama T, Tanii H, Okada M.
    • Journal Title

      Neurosci Lett

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Presentation] 不安感受性尺度について遺伝子多型と性差の関連性の検討2012

    • Author(s)
      谷井久志
    • Organizer
      第4回日本不安障害学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-05
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] パニック障害における人格検査と発症年齢に関する検討2010

    • Author(s)
      石栗有美、谷井久志、小西喜昭、池谷真喜子、小山雄一朗、池之山洋平、岡田元宏、貝谷久宣、岡崎祐士
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      広島
    • Year and Date
      2010-10-09
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] パニック障害における脳由来神経栄養因子(BDNF)遺伝子多型と発症年齢の関連性についての検討2010

    • Author(s)
      小西喜昭、谷井久志、石栗有美、池谷真喜子、小山雄一朗、池之山洋平、岡田元宏、貝谷久宣、岡崎祐士
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      広島
    • Year and Date
      2010-10-07
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Bio-Psycho-Social-Spiritual Perspect of Panic Disorder, Up to Date of Psychobiology2010

    • Author(s)
      谷井久志
    • Organizer
      第2回日本不安障害学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Up to Date of Psychobiology2010

    • Author(s)
      谷井久志
    • Organizer
      第2回日本不安障害学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Association between sigma1 receptor gene A61C (GIn2Pro) and serotonin receptor 1A promoter -1019C>G polymorphism and panic disorder in Japanese population2009

    • Author(s)
      小西喜昭, 谷井久志, 他
    • Organizer
      第17回精神科遺伝学世界会議
    • Place of Presentation
      サンディエゴ (米国)
    • Year and Date
      2009-11-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] パニック障害における広場恐怖やうつ病の合併に関する性格特性と性差に関する検討2009

    • Author(s)
      谷井久志、石栗知美、西村幸香、原直美、井上顕、岡田元宏、貝谷久宣、岡崎祐士
    • Organizer
      第105回日本精神神経学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-08-21
    • Related Report
      2011 Final Research Report
  • [Presentation] パニック障害における広場恐怖やうつ病の合併に関する性格特性と性差に関する検討2009

    • Author(s)
      谷井久志, 石栗知美, 他
    • Organizer
      第105回日本精神神経学会学術総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-08-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] パニック障害におけるSigmal受容体遺伝子多型とNIRSによる脳機能測定の関連性について2009

    • Author(s)
      谷井久志、西村幸香、井上顕、細川琴美、小西喜昭、貝谷久宣、岡崎祐士
    • Organizer
      第11回光脳機能イメージング研究会
    • Year and Date
      2009-07-18
    • Related Report
      2011 Final Research Report
  • [Presentation] パニック障害における Sigma 1受容体遺伝子多型とNIRSによる脳機能測定の関連性について2009

    • Author(s)
      谷井久志, 小西喜昭, 他
    • Organizer
      第11回日本光脳機能イメージング研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] パニック障割における遺伝子多型と知的機能検査に関する検討2009

    • Author(s)
      谷井久志, 細川琴美, 他
    • Organizer
      第31回日本生物学的精神医学会
    • Place of Presentation
      京都
    • Year and Date
      2009-04-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] パニック障害における遺伝子多型と知的機能検査に関する検討2009

    • Author(s)
      谷井久志、細川琴美、西村幸香、石栗知美、前田阿紀、萩原康輔、井上顕、小西喜昭、原直美、岡田元宏、貝谷久宣、岡崎祐士
    • Organizer
      第31回日本生物学的精神医学会
    • Place of Presentation
      京都
    • Year and Date
      2009-04-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Association between sigma1 receptor gene A61C(Gln2Pro) and serotonin receptor 1A promoter-1019C> G polymorphism and panic disorder in Japanese population2009

    • Author(s)
      Yoshiaki Konishi, Hisashi Tanii, Takeshi Otowa, Tsukasa Sasaki, Hisanobu Kaiya, and Yuji Okazaki
    • Organizer
      XVIIth World Congress of psychiatric Genetics
    • Place of Presentation
      San Diego
    • Related Report
      2011 Final Research Report
  • [Book] ストレス科学事典2011

    • Author(s)
      谷井久志
    • Publisher
      実務教育出版社
    • Related Report
      2011 Final Research Report
  • [Book] 「双生児研究」ストレス科学事典P.657-6582011

    • Author(s)
      谷井久志
    • Total Pages
      2
    • Publisher
      実務教育出版社
    • Related Report
      2011 Annual Research Report
  • [Book] 「難治性うつ病にヂュロキセチンとミルタザピンを併用した一例」実地医家のためのうつ病治療症例集、P.109-1112011

    • Author(s)
      谷井久志
    • Total Pages
      3
    • Publisher
      医薬ジャーナル社
    • Related Report
      2011 Annual Research Report
  • [Book] 「精神科における診断書」精神科研修ノート、P.502-5032011

    • Author(s)
      谷井久志
    • Total Pages
      2
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report
  • [Book] 疾患と治療III2010

    • Author(s)
      谷井久志
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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