Realization of near-infrared spectroscopy (NIRS) as a clinical examination for social cognitive dysfunction in schizophrenia and mood disorders.
| Project/Area Number |
21591506
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Gunma University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
FUKUDA Masato 群馬大学, 大学院・医学系研究科, 准教授 (20221533)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 統合失調症 / 気分障害 / NIRS / 脳機能 |
|---|
| Research Abstract |
An experimental setting has been successfully established to reveal characteristics of social cognition dysfunction as a clinical examination during a face-to-face conversation task of two subjects using near-infrared spectroscopy(NIRS)owing to its high time resolution and noninvasiveness. Employing the established setting, brain substrates of social cognition were investigated in 8patients with schizophrenia, 10patients with major depressive disorder, 10patients with bipolar disorder, and 10healthy subjects. All the four groups demonstrated overall frontal activations during the task in the decreasing order of the control, schizophrenia, depression, and bipolar groups, and its fluctuation during the speaking vs. listening periods was also observed in the decreasing order of the control, depression, bipolar and schizophrenia groups. These results suggest possible availability of NIRS examination just during interpersonal activities for the objective assessment of social cognition deficits in psychiatric disorders.
|
Report
(4 results)
Research Products
(17 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] NIRSとMEGによる気分障害の研究(シンポジウム3:気分障害研究UP TO DATE)2010
Author(s)
武井雄一, 須田真史, 青山義之, 成田秀幸, 成田耕介, 石毛陽子, 服部卓, 桜井敬子, 亀山正樹, 福田正人, 三國雅彦
Organizer
第32回日本生物学的精神医学会
Place of Presentation
小倉
Related Report
-
[Presentation] 統合失調症における認知課題時の賦活反応性の性・年齢による影響-近赤外線スペクトロスコピーを用いた検討2010
Author(s)
青山義之, 山岸裕, 須田真史, 武井雄一, 佐藤利正, 藤原和之, 松川幸英, 成田秀幸, 桜井敬子, 亀山正樹, 成田耕介, 福田正人, 三國雅彦
Organizer
第5回日本統合失調症学会
Place of Presentation
福岡
Related Report
-
