MEG gamma network abnormality in schizophrenia

• Project/Area Number: 21591516
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Osaka University
• Principal Investigator: ISHII Ryouhei 大阪大学, 医学系研究科, 助教 (40372619)
• Co-Investigator(Kenkyū-buntansha): IWASE Masao 大阪大学, 医学系研究科, 助教 (60362711) ; TAKEDA Masatoshi 大阪大学, 医学系研究科, 教授 (00179649) ; 橋本 亮太 大阪大学, 連合小児発達学研究科, 特任准教授(常勤) (10370983)
• Project Period (FY): 2009 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
• Keywords: 統合失調症 / 脳磁図 / ガンマ帯域活動 / ネットワーク異常 / 脆弱性遺伝子 / 脳波 / ワーキングメモリ / 精神生理学 / 空間フィルタ法

Research Abstract

Twenty-two SCZ patients and 20 age- and gender-matched HC were enrolled in this study. MEG measurement in resting eyes-open/eyes-closed states for each 10 seconds and to repeat for 8 trials was performed in both groups. The comparisons of mean ERS or ERD values between two groups were also performed using unpaired, two-tailed t-test in Brain Voyager software (BV). A significant positive correlation was found between upper alpha ERS in the left posterior MTG and scores on visual memory subtests of the Wechsler Memory Scale-Revised in SCZ patients (rho=0.57, 0.48; p<0.05). These findings indicate impaired brain oscillatory activity in simple paradigm of resting eyes-open/eyes-closed states in SCZ patients, manifested as decreased upper alpha ERS in the left posterior MTG.

Research Products

• [Journal Article] New possibility of traditional Chinese medicine for the treatments for behavioral and psychiatric symptoms of dementia. (2012)
  • Author(s): Kung FC, Ishii R, Liu HC, Takeda M.
  • Journal Title: Clinical Interventions in Aging Volume: 7 Pages: 393-396
• [Journal Article] Heartbeat evoked potentials: a new possible clinical biomarker for depression based on the somatic marker hypothesis. (2012)
  • Author(s): Ishii R, Canuet L.
  • Journal Title: Clinical Neurophysiology Volume: 123(10) Pages: 1899-1900
• [Journal Article] Publication criteria for evoked magnetic fields of the human brain: a proposal. (2012)
  • Author(s): Ozaki I, Shiraishi H, Kamada K, Kameyama S, Tsuyuguchi N, Yumoto M, Watanabe Y, Hirata M, Ishii R, Iguchi Y, Kimura T, Takino R, Hashimoto I.
  • Journal Title: Clinical Neurophysiology Volume: 123(11) Pages: 2116-2121
• [Journal Article] Influencia del genotipo APOE sobre la actividad cerebral en la enfermedad de Alzheimer. (2012)
  • Author(s): Canuet L, Tellado I, Couceiro V, Fraile C, Fernandez-Novoa L, Ishii R, Takeda M, Cacabelos R.
  • Journal Title: Gen-T The EuroEspes Journal
• [Journal Article] Induced oscillatory responses during the Sternberg's visual memory task in patients with Alzheimer's disease and mild cognitive impairment. (2012)
  • Author(s): Kurimoto R, Ishii R, Canuet L, Ikezawa K, Iwase M, Azechi M, Aoki Y, Ikeda S, Yoshida T, Takahashi H, Nakahachi T, Kazui H, Takeda M.
  • Journal Title: Neuroimage Volume: 59(4) Pages: 4132-4140
• [Journal Article] Relationship of prepulse inhibition to temperament and character in healthy Japanese subjects. (2012)
  • Author(s): Takahashi H, Iwase M, Yasuda Y, Ohi K, Fukumoto M, Iike N, Yamamori H, Nakahachi T, Ikezawa K, Azechi M, Canuet L, Ishii R, Kazui H, Hashimoto R, Takeda M.
  • Journal Title: Neurosci Res Volume: 72(2) Pages: 187-193
• [Journal Article] Resting-State Network Disruption and APOE Genotype in Alzheimer's Disease: A lagged Functional Connectivity Study . (2012)
  • Author(s): Canuet L, Tellado I, Couceiro V, Fraile C, Fernandez-Novoa L, Ishii R, Takeda M, Cacabelos R.
  • Journal Title: PLoS One Volume: 7(9)
• [Journal Article] Induced oscillatory responses during the Sternberg's visual memory task in patients with Alzheimer's disease and mild cognitive impairment (2012)
  • Author(s): Kurimoto R, Ishii R, Canuet L, Ikezawa K, Iwase M, Azechi M, Aoki Y, Ikeda S, Yoshida T, Takahashi H, Nakahachi T, Kazui H, Takeda M
  • Journal Title: Neuroimage Volume: 59(4) Issue: 4 Pages: 4132-4140
  • DOI: 10.1016/j.neuroimage.2011.10.061
  • Peer Reviewed
• [Journal Article] "Resting-State Network Disruption and APOE Genotype in Alzheimer’s Disease: A lagged Functional Connectivity Study" (2012)
  • Author(s): Canuet L, Tellado I, Couceiro V, Fraile C, Fernandez-Novoa L, Ishii R, Takeda M, Cacabelos R
  • Journal Title: PLoS One Volume: 7(9) Issue: 9 Pages: e46289-e46289
  • DOI: 10.1371/journal.pone.0046289
  • Peer Reviewed
• [Journal Article] "Heartbeat evoked potentials: a new possible clinical biomarker for depression based on the somatic marker hypothesis " (2012)
  • Author(s): Ishii R, Canuet L
  • Journal Title: Clinical Neurophysiology Volume: 123(10) Issue: 10 Pages: 1899-1900
  • DOI: 10.1016/j.clinph.2012.03.002
  • Peer Reviewed
• [Journal Article] New possibility of traditional Chinese medicine for the treatments for behavioral and psychiatric symptoms of dementia (2012)
  • Author(s): "Kung FC, Ishii R, Liu HC, Takeda M "
  • Journal Title: Clinical Interventions in Aging Volume: 7 Pages: 393-396
  • DOI: 10.2147/cia.s36509
  • Peer Reviewed
• [Journal Article] Relationship of prepulse inhibition to temperament and character in healthy Japanese subjects (2012)
  • Author(s): Takahashi H, Iwase M, Yasuda Y, Ohi K, Fukumoto M, Iike N, Yamamori H, Nakahachi T, Ikezawa K, Azechi M, Canuet L, Ishii R, Kazui H, Hashimoto R, Takeda M
  • Journal Title: Neurosci Res Volume: 72(2) Issue: 2 Pages: 187-193
  • DOI: 10.1016/j.neures.2011.10.009
  • Peer Reviewed
• [Journal Article] Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy. (2011)
  • Author(s): Canuet L, Ishii R, Pascual-Marqui RD, Iwase M, Kurimoto R, Aoki Y, Ikeda S, Takahashi H, Nakahachi T, Takeda M.
  • Journal Title: PLoS One. Volume: 6(11)
• [Journal Article] Psychopathology and working memory-induced activation of the prefrontal cortex in schizophrenia-like psychosis of epilepsy: evidence from Magnetoencephalography. (2011)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Takahashi H, Currais A, Azechi M, Aoki Y, Nakahachi T, Soriano S, Takeda M.
  • Journal Title: Psychiatry Clin Neurosci. Volume: 65
• [Journal Article] Schizophrenia-like psychosis associated with right parietal meningioma. (2011)
  • Author(s): Canuet L, Ikezawa K, Ishii R, Aoki Y , Iwase M, Takeda M.
  • Journal Title: J Neuropsychiatry Clinical Neurosci Volume: 23(3)
• [Journal Article] Psychopathology and working memory-induced activation of the prefrontal cortex in schizophrenia-like psychosis of epilepsy : Evidence from magnetoencephalography (2011)
  • Author(s): Canuet L, et al
  • Journal Title: Psychiatry Clin Neurosci Volume: 65(2) Pages: 183-190
  • Peer Reviewed
• [Journal Article] Decreased alpha event-related synchronization in the left posterior temioral cortex in schizophrenia : a magnetoencephalography-beamformer study (2011)
  • Author(s): Ikezawa K, et al
  • Journal Title: Neurosci Res Volume: 71(3) Issue: 3 Pages: 235-243
  • DOI: 10.1016/j.neures.2011.07.1819
  • Peer Reviewed
• [Journal Article] Resting-State EEG Source Localization and Functional Connectivity in Schizophrenia-like Psychosis of Epilepsy (2011)
  • Author(s): Canuet L, et al
  • Journal Title: PLoS One Volume: 6(11) Issue: 11 Pages: e27863-e27863
  • DOI: 10.1371/journal.pone.0027863
  • Peer Reviewed
• [Journal Article] Frontal shift of posterior alpha activity is correlated with cognitive impairment in early Alzheimer's disease: a magnetoencephalography-beamformer study. (2010)
  • Author(s): Ishii R, Canuet L, Kurimoto R, Ikezawa K, Aoki Y, Azechi M, Takahashi H,Nakahachi T, Iwase M, Kazui H, Takeda M.
  • Journal Title: Psychogeriatrics Volume: 10(3) Pages: 138-43
  • NAID: 10029771121
• [Journal Article] Frontal cortex activation associated with speeded processing of visuospatial working memory revealed by multichannel near-infrared spectroscopy during Advanced Trail Making Test performance. (2010)
  • Author(s): Nakahachi T, Ishii R, Iwase M, Canuet L, Takahashi H, Kurimoto R, Ikezawa K,Azechi M, Kajimoto O, Takeda M.
  • Journal Title: Behav Brain Res Volume: 215(1) Pages: 21-7
• [Journal Article] Association study of KIBRA gene with memory performance in a Japanese population (2010)
  • Author(s): Yasuda Y, Hashimoto R, Ohi K, Fukumoto M, Takamura H, Iike N, Yoshida T, Hayashi N, Takahashi H, Yamamori H, Morihara T, Tagami S, Okochi M, TanakaT,Kudo T, Kamino K, Ishii R, Iwase M, Kazui H, Takeda M.
  • Journal Title: World J Biol Psychiatry Volume: 11(7) Pages: 852-7
• [Journal Article] Post-movement beta rebound abnormality as indicator of mirror neuron system dysfunction in autistic spectrum disorder:an MEG study. (2010)
  • Author(s): Honaga E, Ishii R, Kurimoto R, Canuet L, Ikezawa K, Takahashi H, Nakahachi T, Iwase M, Mizuta I, Yoshimine T, Takeda M.
  • Journal Title: Neurosci Lett Volume: 478(3) Pages: 141-5
• [Journal Article] Relationship between prepulse inhibition of acoustic startle response and schizotypy in healthy Japanese subjects. (2010)
  • Author(s): Takahashi H, Iwase M, Canuet L, Yasuda Y, Ohi K, Fukumoto M, Iike N, Nakahachi T, Ikezawa K, Azechi M, Kurimoto R, Ishii R, Yoshida T, Kazui H, Hashimoto R,Takeda M.
  • Journal Title: Psychophysiology Volume: 47(5) Pages: 831-7
• [Journal Article] The chitinase 3-like 1 gene and schizophrenia: evidence from a multi-center case-control study and meta-analysis. (2010)
  • Author(s): Ohi K, Hashimoto R, Yasuda Y, Yoshida T, Takahashi H, Iike N, Iwase M, Kamino K, Ishii R, Kazui H, Fukumoto M, Takamura H, Yamamori H, Azechi M, Ikezawa K,Tanimukai H, Tagami S, Morihara T, Okochi M, Yamada K, Numata S, Ikeda M, Tanaka T, Kudo T, Ueno S
  • Journal Title: Schizophr Res Volume: 116(2-3) Pages: 126-32
• [Journal Article] Working memory abnormalities in chronic interictal epileptic psychosis and schizophrenia revealed by magnetoencephalography. (2010)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Takahashi H, Currais A, Azechi M, Nakahachi T, Hashimoto R, Takeda M.
  • Journal Title: Epilepsy Behav Volume: 17(1) Pages: 109-19
• [Journal Article] Discriminant analysis in schizophrenia and healthy subjects using prefrontal activation during frontal lobe tasks: a near-infrared spectroscopy. (2010)
  • Author(s): Azechi M, Iwase M, Ikezawa K, Takahashi H, Canuet L, Kurimoto R, Nakahachi T, Ishii R, Fukumoto M, Ohi K, Yasuda Y, Kazui H, Hashimoto R, Takeda M.
  • Journal Title: Schizophr Res Volume: 117(1) Pages: 52-60
• [Journal Article] Frontal shift of posterior alpha activity is correlated with cognitive impairment in early Alzheimer's disease : a magnetoencephalography-beamformer study. (2010)
  • Author(s): Ishii R, et al.
  • Journal Title: Psychogeriatrics Volume: 10 Pages: 138-143
  • Peer Reviewed
• [Journal Article] Frontal cortex activation associated with speeded processing of visuospatial working memory revealed by multichannel near-infrared spectroscopy during Advanced Trail Making Test performance. (2010)
  • Author(s): Nakahachi T, et al.
  • Journal Title: Behav Brain Res Volume: 215 Pages: 21-27
  • Peer Reviewed
• [Journal Article] Working memory abnormalities in chronic interictal epileptic psychosis and schizophrenia revealed by magnetoencephalography. (2010)
  • Author(s): Canuet L, et al.
  • Journal Title: Epilepsy Behav Volume: 17 Pages: 109-119
  • Peer Reviewed
• [Journal Article] Discriminant analysis in schizophrenia and healthy subjects using prefrontal activation during frontal lobe tasks : A near-infrared spectroscopy (2010)
  • Author(s): Azechi M, et al.
  • Journal Title: Schizophrenia Research 117 Pages: 52-60
  • Peer Reviewed
• [Journal Article] Cortical oscillatory power changes during auditory oddball task revealed by spatially filtered magnetoencephalography. (2009)
  • Author(s): Ishii R, Canuet L, Herdman A, Gunji A, Iwase M, Takahashi H, Nakahachi T, Hirata M, Robinson SE, Pantev C, Takeda M.
  • Journal Title: Clin Neurophysiol. Volume: 120(3) Pages: 497-504
• [Journal Article] Factors associated with impaired quality of life in younger and older adults with epilepsy . (2009)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Azechi M, Takahashi H, Nakahachi T, Teshima Y, Takeda M.
  • Journal Title: Epilepsy Res Volume: 83(1) Pages: 58-65
• [Journal Article] TATA box-binding protein gene is associated with risk for schizophrenia, age at onset and prefrontal function. (2009)
  • Author(s): Ohi K, Hashimoto R, Yasuda Y, Kiribayashi M, Iike N, Yoshida T, Azechi M, Ikezawa K, Takahashi H, Morihara T, Ishii R, Tagami S, Iwase M, Okochi M, Kamino K, Kazui H, Tanaka T, Kudo T, Takeda M.
  • Journal Title: Genes Brain Behav Volume: 8(4) Pages: 473-480
• [Journal Article] Neuroimaging studies in patients with Charles Bonnet Syndrome. (2009)
  • Author(s): Kazui H, Ishii R, Yoshida T, Ikezawa K, Takaya M, T okunaga H, Tanaka T, Takeda M.
  • Journal Title: Psychogeriatrics Volume: 9(2) Pages: 77-84
  • NAID: 10025638897
• [Journal Article] Impaired regional hemodynamic response in schizophrenia during multiple prefrontal activation tasks: A two-channel near-infrared spectroscopy study . (2009)
  • Author(s): Ikezawa K, Iwase M, Ishii R, Azechi M, Canuet L, Ohi K, Yasuda Y, Iike N, Kurimoto R, Takahashi H, Nakahachi T, Sekiyama R, Yoshida T, Kazui H, Hashimoto R, Takeda M.
  • Journal Title: Schizophr Res Volume: 108 Pages: 93-103
• [Journal Article] Association study of the G72 gene with schizophrenia in a Japanese population: a multicenter study. (2009)
  • Author(s): Ohi K, Hashimoto R, Yasuda Y, Yoshida T, Takahashi H, Iike N, Fukumoto M, Takamura H, Iwase M, Kamino K, Ishii R, Kazui H, Sekiyama R, Kitamura Y, Azechi M, Ikezawa K, Kurimoto R, Kamagata E, Tanimukai H, Tagami S, Morihara T, Ogasawara M, Okochi M, Tokun
  • Journal Title: Schizophr Res. Volume: 109(1-3) Pages: 80-5
• [Journal Article] TATA box-binding protein gene is associated with risk for schizophrenia, age at onset and prefrontal function (2009)
  • Author(s): Ohi K, et al.
  • Journal Title: Genes, Brain and Behavior 8 Pages: 473-480
  • Peer Reviewed
• [Journal Article] The chitinase 3-like 1 gene and schizophrenia: evidence from a multi-center case-control study and meta-analysis (2009)
  • Author(s): Ohi K, et al.
  • Journal Title: Schizophrenia Research 116 Pages: 126-132
  • Peer Reviewed
• [Journal Article] Factors associated with impaired quality of life in younger and older adults with epilepsy (2009)
  • Author(s): Canuet L, et al.
  • Journal Title: Epilepsy Research 83 Pages: 58-65
  • Peer Reviewed
• [Journal Article] Cortical oscillatory power changes during auditory oddball task revealed by spatially filtered magnetoencephalography (2009)
  • Author(s): 石井良平, et al.
  • Journal Title: Clinical Neurophysiology 120 Pages: 497-504
  • Peer Reviewed
• [Journal Article] 自発脳磁図とその異常 (2009)
  • Author(s): 石井良平, ら
  • Journal Title: 臨床検査 53 Pages: 1003-1009
• [Journal Article] 統合失調症の安静開閉眼時における律動脳磁場活動変化の検討 (2009)
  • Author(s): 池澤浩二, ら
  • Journal Title: 日本生体磁気学会誌 22 Pages: 208-209
  • Peer Reviewed
• [Journal Article] 認知症のMEG研究の最新知見 (2009)
  • Author(s): 石井良平, ら
  • Journal Title: Cognition and Dementia 8 Pages: 105-108
• [Journal Article] MEGの臨床応用の現状とガンマ帯域活動解析の最新知見 (2009)
  • Author(s): 石井良平, ら
  • Journal Title: 脳と精神の医学 20 Pages: 119-206
  • NAID: 10028262311
• [Presentation] シンポジム３:脳機能イメージング研究の新展開―技術編 適応型開口合成法を用いた生体磁場計測からの信号源再構成の臨床応用 (2012)
  • Author(s): 石井良平
  • Organizer: 第14回日本ヒト脳機能マッピング学会
  • Place of Presentation: 札幌市
  • Invited
• [Presentation] シンポジウム25：発達障害の病態生理解明の最先端 自閉症スペクトラム障害のミラーニューロンシステムの機能異常：脳磁図による解析 (2012)
  • Author(s): 石井良平、補永栄子、栗本龍、青木正典、池田俊一郎、畑真弘、高橋秀俊、 中鉢貴行、 岩瀬真生、 水田一郎、 武田雅俊
  • Organizer: 第34回日本生物学的精神医学会
  • Place of Presentation: 神戸市
  • Invited
• [Presentation] 教育セミナー：てんかんと精神医学的合併症 (2012)
  • Author(s): 石井良平
  • Organizer: 第46回日本てんかん学会、、2012.10.11-12
  • Place of Presentation: 東京都
  • Invited
• [Presentation] シンポジウム：脳波ルネッサンス DIMENSIONとNAT(Neuronal Activity Topography)による新しい認知症の診断法 治療可能な認知症への応用【特発性正常圧水頭症】 (2012)
  • Author(s): 青木保典、數井裕光、石井良平、武者利光、松崎晴康、今城郁、和田民樹、山本大介、岩瀬真生、武田雅俊
  • Organizer: 第31回日本認知症学会
  • Place of Presentation: つくば市
  • Invited
• [Presentation] Symposium: Electrophysiology, New Insight through Psychophysiological Studyfor Exploring Psychopathology of Schizophrenia Patients: Clinical Application of MEG in Schizophrenia (2011)
  • Author(s): Ishii R
  • Organizer: 2nd Asian Congress on Schizophrenia Research
  • Place of Presentation: The Ritz Carlton Soeul, Soeul, South Korea
  • Year and Date: 2011-02-11
• [Presentation] Cognitive and psychopathological disturbance in schizophrenia-like epilepsy psychosis: a neuroimaging magnetoencephalography study (2011)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Takahashi H, Azechi M, Aoki Y, Nakahachi T, Takeda M.
  • Organizer: 2nd Asian Congress on Schizophrenia Research
  • Place of Presentation: The Ritz Carlton Soeul, Soeul, South Korea
  • Year and Date: 2011-02-11
• [Presentation] Relationship of prepulse Inhibition to personality dimensions in Japanese patients with schizophrenia. (2011)
  • Author(s): Hidetoshi Takahashi, Masao Iwase, Yuka Y asuda, Hidenaga Yamamori, Kazutaka Ohi, Motoyuki Fukumoto, Leonides Canuet, Ryouhei Ishii, Hiroaki Kazui, Ryota Hashimoto, Masatoshi Takeda.
  • Organizer: 10th World Congress of Biological Psychiatry
  • Place of Presentation: Prague Congress Centre , Prague, Czech Republic
• [Presentation] Two-channel near infrared spectroscopy (NIRS) activation curves of oxyhemoglobin during frontal lobe tasks in schizophrenia. (2010)
  • Author(s): M. Iwase, M. Azechi, K. Ikezawa, R. Ishii, H. Takahashi, T. Nakahachi, L. Canuet, Y. Aoki, R. Kurimoto, H. Kazui, M. Fukumoto, N. Iike, K. Ohi, H. Yamamori, Y. Yasuda, R. Hashimoto, M. Takeda.
  • Organizer: 40th Annual Meeting, Neuroscience 2010
  • Place of Presentation: San Diego Convention Center, San Diego, USA
  • Year and Date: 2010-11-14
• [Presentation] Depressive state: the strongest predictor of quality of life in elderly patients with epilepsy . (2010)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Azechi M, Takahashi H, Nakahachi T, Teshima Y, Takeda M
  • Organizer: The Hong Kong Psychogeriatric Association Annual Scientific Meeting cum Annual General Meeting
  • Place of Presentation: Hong Kong, China
  • Year and Date: 2010-11-06
• [Presentation] Abnormal cortical oscillatory activity in schizophrenia-like psychosis of epilepsy after resection of meningioma (2010)
  • Author(s): Ishii R, et al.
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: 神戸国際会議場(招待講演)
  • Year and Date: 2010-10-30
• [Presentation] Spatially filtered MEG revealed theta and gamma power changes during mental calculation. (2010)
  • Author(s): Ishii R, Canuet L, Ishihara T, Aoki Y, Takahashi H, Nakahachi T, Iwase M, Takeda M
  • Organizer: 第33回日本神経科学会大会 Neuro2010
  • Place of Presentation: 神戸コンベンションセンター
• [Presentation] Two-channel near infrared spectroscopy activation curves of oxyhemoglobin during frontal tasks in schizophrenia (2010)
  • Author(s): IwaseM, Azechi M, Ikezawa K, Ishii R, Takahashi H, Nakahachi T, Canuet L, Aoki Y, Kurimoto R, Kazui K, Fukumoto M, Iike N, Ohi K, Yamamori H,Yasuda Y,Hashimoto R,Takeda M
  • Organizer: 第33回日本神経科学会大会 Neuro2010
  • Place of Presentation: 神戸コンベンションセンター
• [Presentation] Platform presentation: Psychiatry & Neuropsychology. Working memory-induced activation and severity of psychopathology in schizophrenia-like psychosis of epilepsy: evidence from Magnetoencephalography. (2010)
  • Author(s): Canuet L, Ishii R, Iwase M, Ikezawa K, Kurimoto R, Takahashi H, Currais A, Azechi M, Nakahachi T, Takeda M.
  • Organizer: The 8th Asian & Oceanian Epilepsy Congress
  • Place of Presentation: Melbourne, Austlaria
• [Presentation] Mirror neuron system dysfunction in autistic spectrum disorder revealed by spatial filtered magnetic encephalography . (2010)
  • Author(s): E. Honaga, R. Ishii, R. Kurimoto, L. Canuet, K. Ikezawa, H. Takahashi, T. Nakahachi, M. Iwase, S. Ukai, T. Yoshimine, M. Takeda.
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Working memory-induced activation and severity of psychopathology in schizophrenia-like psychosis of epilepsy: evidence from magnetoencephalography (2010)
  • Author(s): L. Canuet, R. Ishii, K. Ikezawa, R. Kurimoto, M. Iwase, H. Takahashi, T. Nakahachi, M. Azechi, Y. Aoki, T. Yoshimine, M. Takeda
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Frontal lobe dysfunction and regional hemodynamic changes in major depression: A near infrared spectroscopy study (2010)
  • Author(s): M. Azechi, M. Iwase, R. Ishii, K. Ikezawa, L. Canuet, R. Kurimoto, H. Takahashi, T. Nakahachi, N. Iike, M. Fukumoto, K. Ohi, H. Yamamori, Y. Yasuda, R. Hashimoto, M. Takeda
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Abnormal cortical oscillatory activity in schizophrenia-like psychosis of epilepsy after resection of meningioma (2010)
  • Author(s): R. Ishii, L. Canuet, K. Ikezawa, R. Kurimoto, M. Iwase, H. Takahashi, T. Nakahachi, M. Azechi, Y. Aoki, T. Yoshimine, M. Takeda
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Two-channel NIRS activation curves of oxyhemoglobin during frontal lobe tasks in schizophrenia (2010)
  • Author(s): M. Iwase, M. Azechi, K. Ikezawa, R. Ishii, H. Takahashi, T. Nakahachi, L. Canuet, R. Kurimoto, H. Kazui, M. Fukumoto, N. Iike, K. Ohi, H. Yamamori, Y. Yasuda, R. Hashimoto, M. Takeda
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Multichannel NIRS revealed frontal cortex activation associated with speeded processing of visuospatial working memory (2010)
  • Author(s): T. Nakahachi, R. Ishii, M. Iwase, L. Canuet, H. Takahashi, R. Kurimoto, K. Ikezawa, M. Azechi, Y. Aoki, O. Kajimoto, M. Takeda
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Assessment of stress states based on EEG activity using multiple regression analysis (2010)
  • Author(s): T. Hayashi, E. Okamoto, S. Ukai, K. Shinosaki, R. Ishii, Y. Mizuno-Matsumoto
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] Relationship between personality stability and brain reaction area under the emotional stimuli (2010)
  • Author(s): Y. Mizuno-Matsumoto, T. Hayashi, E. Okamoto, T. Asakawa, R. Ishii, S. Ukai, K. Shinosaki
  • Organizer: The 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
• [Presentation] 統合失調症における作業記憶課題時の脳磁場活動変化に関する検討 (2009)
  • Author(s): 石井良平, ら
  • Organizer: 薬物治療研究報告会
  • Place of Presentation: 千里ライフサイエンスセンター
  • Year and Date: 2009-12-05
• [Presentation] 脳磁図による軽度アルツハイマー病患者、軽度認知障害患者における基礎律動減衰の評価 (2009)
  • Author(s): 石井良平, ら
  • Organizer: 第39回日本臨床神経生理学会
  • Place of Presentation: 北九州国際会議場
  • Year and Date: 2009-11-20
• [Presentation] 近赤外線スペクトロスコピー (NIRS) を用いた正常圧水頭症のCSF tap test 中における脳血流変化の検討 (2009)
  • Author(s): 疇地道代, ら
  • Organizer: 第39回日本臨床神経生理学会
  • Place of Presentation: 北九州国際会議場
  • Year and Date: 2009-11-18
• [Presentation] 2-ch-NIRSによる前頭葉課題施行中の酸化ヘモグロビン濃度の賦活曲線特性-統合失調症と健常者の比較 (2009)
  • Author(s): 岩瀬真生, ら
  • Organizer: 第39回日本臨床神経生理学会
  • Place of Presentation: 北九州国際会議場
  • Year and Date: 2009-11-18
• [Presentation] 統合失調症患者の作業記憶課題時における脳磁場活動変化に関する検討 (2009)
  • Author(s): 池澤浩二, ら
  • Organizer: 第39回日本臨床神経生理学会
  • Place of Presentation: 北九州国際会議場
  • Year and Date: 2009-11-18
• [Presentation] NIRSを用いた大うつ病性障害の前頭葉機能と局所脳血流量変化の検討 (2009)
  • Author(s): 疇地道代, ら
  • Organizer: 第16回日本未病システム学会
  • Place of Presentation: 千里ライフサイエンスセンター
  • Year and Date: 2009-11-01
• [Presentation] 近赤外分光法による組織酸素化指標を用いた統合失調症の前頭低活性の検討 (2009)
  • Author(s): 岩瀬真生, ら
  • Organizer: 第16回日本未病システム学会
  • Place of Presentation: 千里ライフサイエンスセンター
  • Year and Date: 2009-10-31
• [Presentation] 「人はなぜ笑うのか?」 : 笑いの脳内メカニズム (2009)
  • Author(s): 岩瀬真生
  • Organizer: 日本学術会議近畿地区会議学術講演会
  • Place of Presentation: 京都大学百周年時計台記念館
  • Year and Date: 2009-10-11
• [Presentation] Hypofrontality in schizophrenia detected by the measurement of tissue oxygeneation index using NIRS (2009)
  • Author(s): Iwase M, Azechi M, Ikezawa K, Ishii R, Leonides C, Kurimoto R, Hidetoshi T, Nakahachi T, Kazui H, Fukumoto M, Iike N, Ohi K, Yasuda Y, Hashimoto R, Takeda M
  • Organizer: The 32nd Annual Meeting of the Japan Neuroscience Society
  • Place of Presentation: Nagoya
  • Year and Date: 2009-09-18
• [Presentation] 近赤外線スペクトロスコピーを用いた正常圧水頭症のCSF tap test による脳血流変化の検討 (2009)
  • Author(s): 疇地道代, ら
  • Organizer: 第11回日本光脳機能イメージング研究会
  • Place of Presentation: 星陵会館
  • Year and Date: 2009-07-18
• [Presentation] Discriminant analysis in schizophrenia and healthy subjects using preforntal activation during forntal lobe tasks : a near-infrared spectroscopy study (2009)
  • Author(s): 疇地道代, et al.
  • Organizer: The 9th World Congress of Biological Psychiatry
  • Place of Presentation: France, Paris
  • Year and Date: 2009-07-01
• [Presentation] NIRSを用いた大うつ病性障害の前頭葉機能と局所脳血流変化の検討 (2009)
  • Author(s): 疇地道代, ら
  • Organizer: 第31回日本生物学的精神医学会
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2009-04-24
• [Presentation] Discriminant analysis in schizophrenia and healthy controls using preforntal activation during forntal lobe tasks: a near-infrared spectroscopy study (2009)
  • Author(s): Azechi M, Iwase M, Ikezawa K, Canuet L, Kurimoto R, Takahashi H, Nakahachi T, Ishii R, Fukumoto M, Iike N, Ohi K, Yasuda Y, Kazui H, Hashimoto R, Takeda M.
  • Organizer: 9th World Congress of Biological Psychiatry Paris
  • Place of Presentation: France
• [Presentation] A case report of Alzheimer disease with Presenilin-1 mutation (Met233Leu) showing a new phenotype (2009)
  • Author(s): Takaya M, Kazui H, Ikezawa K, Kurimoto R, Yamamoto K, Morihara T, Ishii R, Tokunaga H, Takeda M
  • Organizer: Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD)
  • Place of Presentation: Messe Wien Exhibition and Congress Center, Vienna, Austria
• [Presentation] MEG oscillatory activity during eyes-open/eyes-closed resting state in schizophrenia (2009)
  • Author(s): Ikezawa K, Ishii R, Iwase M, Kurimoto R, Canuet L, Takahashi H, Nakahachi T, Azechi M, Ohi K, Fukumoto K, Takamura H, Yasuda Y, Iike N, Takaya M, Kazui H, Hashimoto R, Yoshimine T, Takeda M
  • Organizer: 2nd conference of International Society for the Advancement of Clinical Magnetoencephalography
  • Place of Presentation: Greece
• [Presentation] Frontal shift of posterior alpha activity in early Alzheimer's disease revealed by MEG beamformer analysis (2009)
  • Author(s): Ishii R, Kurimoto R, Ikezawa k, Canuet L, Azechi M, Takahashi H, Nakahachi T, Iwase M, Kazui H, Takeda M
  • Organizer: The International Symposium on Early Detection and Rehabilitation Technology of Dementia
  • Place of Presentation: Okayama
• [Presentation] 統合失調症の安静開閉眼時における律動脳磁場活動変化の検討 (2009)
  • Author(s): 池澤浩二, ら
  • Organizer: 第24回日本生体磁気学会
  • Place of Presentation: 金沢
• [Presentation] P300に関連する前頭部律動の領域的可視化 -SAM 法とSPM99, Permutation 法による解析- (2009)
  • Author(s): 石井良平, ら
  • Organizer: 第24回日本生体磁気学会
  • Place of Presentation: 金沢
• [Presentation] アルツハイマー病, 軽度認知機能障害患者における安静開閉眼時のα波出現に関する評価 (2009)
  • Author(s): 池澤浩二, ら
  • Organizer: 第16回日本未病システム学会
  • Place of Presentation: 千里ライフサイエンスセンター
• [Presentation] MEG oscillatory activity during eyes-open/eyes-closed resting state in schizophrenia (2009)
  • Author(s): 池澤浩二, et al.
  • Organizer: 2nd conference of International Society for the Advancement of Clinical Magnetoencephalography
  • Place of Presentation: Greece, Athene
• [Presentation] MEG source-power changes during working memory performance in chronic interictal psychosis (2009)
  • Author(s): Canuet L, et al.
  • Organizer: 2nd conference of International Society for the Advancement of Clinical Magnetoencephalography
  • Place of Presentation: Greece, Athene
• [Book] 精神疾患とNIRS 福田正人 (編) (2009)
  • Author(s): 池澤浩二, ら
  • Total Pages: 252
  • Publisher: 中山書店