Project/Area Number |
21591551
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Radiation science
|
Research Institution | Nagasaki University (2010-2011) University of Fukui (2009) |
Principal Investigator |
KUDO Takashi 長崎大学, 大学院・医歯薬学総合研究科, 教授 (20330300)
|
Co-Investigator(Kenkyū-buntansha) |
NAKANO Akira 福井大学, 医学部, 助教 (20334815)
ARAKAWA Kenichirou 福井大学, 医学部, 助教 (80401967)
OKAZAWA Hidehiko 福井大学, 高エネルギー医学研究センター, 教授 (50360813)
|
Co-Investigator(Renkei-kenkyūsha) |
OKAZAWA Hidehiko 福井大学, 高エネルギー医学研究センター, 教授 (50360813)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 核医学(PETを含む) / 炭素11標識酢酸 / 心筋エネルギー効率 / ポジトロン断層撮影 / 心筋燃費 / エネルギー消費効率 / 心電図同期収集 |
Research Abstract |
Using positron emission tomography(PET), especially C-11 acetate PET, we performed simultaneous measurement of myocardial perfusion, metabolism and cardiac function. We proved that the simultaneous measurement of these three parameters is possible. We can calculate the myocardial energy efficiency using this technique. The measurement of myocardial energy efficiency is useful tool for the evaluation of cardiac pathology such as mitochondrial cardiomyopathy, etc.
|