Evaluation of hepatic portal perfusion by non-contrast-enhanced hepatic MR portal perfusion image : Clinical feasibility and usefulness

• Project/Area Number: 21591558
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: ISODA Hiroyoshi 京都大学, 医学研究科, 准教授 (20309214)
• Co-Investigator(Kenkyū-buntansha): TOGASHI Kaori 京都大学, 医学研究科, 教授 (90135484) ; SHIBATA Toshiya 京都大学, 医学研究科, 准教授 (60162632)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: 放射線 / 臨床 / 核磁気共鳴画像 / 肝臓 / 血流

Research Abstract

Our results in a series of normal volunteers showed that non-contrast-enhanced hepatic MR portal perfusion image could serve a noninvasive method of assessing hepatic portal perfusion. We have demonstrated in a series of patients with hepatic mass that non-contrast-enhanced hepatic MR portal perfusion image can provide good detection of hepatic mass. Non-contrast-enhanced hepatic MR portal perfusion image seems to be a reliable technique to evaluate hepatic mass.

Research Products

• [Journal Article] Non-contrast-enhanced MR angiography of the abdomen (2011)
  • Author(s): Miyazaki M, Isoda H
  • Journal Title: Eur. J Radiology Volume: 80 Issue: 1 Pages: 9-23
  • DOI: 10.1016/j.ejrad.2011.01.093
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced hepatic MR angiography : Do two-dimensional parallel imaging and short tau inversion recovery methods shorten acquisition time without image quality deterioration (2011)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Arizono S, Hirokawa Y, Shibata T, Togashi K
  • Journal Title: Eur. J Radiology Volume: 77 Issue: 1 Pages: 137-142
  • DOI: 10.1016/j.ejrad.2009.05.051
  • Peer Reviewed
• [Journal Article] Contrast Behavior of High-Spatial-Resolution T1-weighted MRimaging at 3. 0 T vs. 1. 5 T. (2011)
  • Author(s): Isoda H, Arizono S, Shimada K, Hirokawa Y, Maetani YS, Kataoka M, Nakamoto Y, Shibata T, Togashi K
  • Journal Title: Clin Imaging Volume: 35 Issue: 2 Pages: 133-138
  • DOI: 10.1016/j.clinimag.2010.04.004
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced MR angiography of the abdomen (2011)
  • Author(s): Miyazaki M, Isoda H
  • Journal Title: Eur J Radiology Volume: 80 Pages: 9-23
  • Peer Reviewed
• [Journal Article] Diffusion tensor MRI of the kidney at 3. 0 and 1. 5Tesla (2010)
  • Author(s): Kido A, Kataoka M, Yamamoto A, Nakamoto Y, Umeoka S, Koyama T, Maetani Y, Isoda H, Tamai K, Morisawa N, Saga T, Mori S, Togashi K
  • Journal Title: Acta Radiol Volume: 51 Issue: 9 Pages: 1059-1063
  • DOI: 10.3109/02841851.2010.504741
  • Peer Reviewed
• [Journal Article] Improved detection of hepatic metastases from pancreatic cancer using periodically rotated overlapping parallel lines with enhanced reconstruction(PROPELLER) technique after SPIO administration (2010)
  • Author(s): Hirokawa Y, Isoda H, Okada T, Arizono S, Shimada K, Yamamoto A, Shibata T, Togashi K
  • Journal Title: Invest Radiol Volume: 45 Issue: 3 Pages: 158-164
  • DOI: 10.1097/rli.0b013e3181d32139
  • Peer Reviewed
• [Journal Article] High spatial resolution 3DMR cholangiography with high sampling efficiency technique(SPACE): Comparison of 3 T vs. 1. 5 T. (2010)
  • Author(s): Arizono S, Isoda H, Maetani YS, Hirokawa Y, Shimada K, Nakamoto Y, Shibata T, Togashi K
  • Journal Title: Eur J Radiology Volume: 73 Issue: 1005 Pages: 144-118
  • DOI: 10.1259/bjr/20594229
  • Peer Reviewed
• [Journal Article] 肝の3D・4D画像診断の臨床動向-CTMRIの3D画像を中心に (2010)
  • Author(s): 磯田裕義、有薗茂樹、嶋田功太郎、柴田登志也、富樫かおり
  • Journal Title: INNER VISION Volume: 25(5) Pages: 32-34
  • URL: http://www.innervision.co.jp/01inner/2010/pdf/iv1005_10.pdf
• [Journal Article] 腹部領域のMR診断 (2010)
  • Author(s): 磯田裕義、有薗茂樹、嶋田功太郎、柴田登志也、富樫かおり
  • Journal Title: 検査と技術 Volume: 38(6) Pages: 397-401
  • URL: http://www.igaku-shoin.co.jp/journalDetail.do?journal=33701
• [Journal Article] 上腹部領域での3T MRI画像診断と可能性 (2009)
  • Author(s): 磯田裕義
  • Journal Title: 映像情報 Volume: 41(1) Pages: 30-35
  • URL: http://www.eizojoho.co.jp/medical/bn/bn200901.html
• [Journal Article] Non-contrast-enhanced MR angiography for selective visualization of the hepatic vein and inferior vena cava with true steady-state free-precession sequence and time-spatial labeling inversion pulses : preliminary results (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Arizono S, Hirokawa Y, Togashi K
  • Journal Title: J Magn Reson Imaging Volume: 29 Issue: 2 Pages: 474-479
  • DOI: 10.1002/jmri.21636
  • Peer Reviewed
• [Journal Article] Diffusion tensor imaging of kidneys with respiratory triggering : optimization of parameters to demonstrate anisotropic structures on fraction anisotropy maps (2009)
  • Author(s): Kataoka M, Kido A, Yamamoto A, Nakamoto Y, Koyama T, Isoda H, Maetani Y, Umeoka S, Tamai K, Saga T, Morisawa N, Mori S, Togashi K
  • Journal Title: J Magn Reson Imaging Volume: 29 Issue: 3 Pages: 736-744
  • DOI: 10.1002/jmri.21669
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced hepatic MR angiography with true steady-state free-precession and time spatial labeling inversion pulse : optimization of the technique and preliminary results (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Maetani Y, Arizono S, Hirokawa Y, Kamae T, Togashi K
  • Journal Title: Eur J Radiology Volume: 70 Issue: 1 Pages: 111-117
  • DOI: 10.1016/j.ejrad.2007.12.010
  • Peer Reviewed
• [Journal Article] Hepatic lesions : improved image quality and detection with the periodically rotated overlapping parallel lines with enhanced reconstruction technique-evaluation of SPIO-enhancedT2-weighted MR images (2009)
  • Author(s): Hirokawa Y, Isoda H, Maetani YS, Arizono S, Shimada K, Shibata T, Togashi K
  • Journal Title: Radiology Volume: 251 Issue: 2 Pages: 388-397
  • DOI: 10.1148/radiol.2512081360
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced MR portography with time-spatial labeling inversion pulses : Comparison of imaging with three-dimensional half-fourier fast spin-echo and true steady-state free-precession sequences (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Maetani Y, Arizono S, Hirokawa Y, Shibata T, Togashi K
  • Journal Title: J Magn Reson Imaging Volume: 29 Issue: 5 Pages: 1140-1146
  • DOI: 10.1002/jmri.21753
  • Peer Reviewed
• [Journal Article] Unenhanced MR Portography With a Half-Fourier Fast Spin-Echo Sequence and Time-Space Labeling Inversion Pulses : Preliminary Results (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Arizono S, Hirokawa Y, Togashi K
  • Journal Title: Am J Roentgenol Volume: 193 Issue: 1 Pages: 106-112
  • DOI: 10.2214/ajr.08.1626
  • Peer Reviewed
• [Journal Article] Unenhanced MR Portography With a Half-Fourier Fast Spin-Echo Sequence and Time-Space Labeling Inversion Pulses : Preliminary Results (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Arizono S, Hiro kawa Y, Togashi K
  • Journal Title: Am J Roentgenol 193 Pages: 106-112
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced MR portography with time-spatial labeling inversion pulses : Comparison of imaging with three-dimensional half-fourier fast spin-echo and true steady-state free-precession sequences. (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Kamae T, Maetani Y, Arizono S, Hirokawa Y, Shibata T, Togashi K
  • Journal Title: J Magn Reson Imaging 29 Pages: 1140-1146
  • Peer Reviewed
• [Journal Article] Non-contrast-enhanced hepatic MR angiography with true steady-statefree-precession and time spatial labeling inversion pulse : optimization of the technique and preliminary results (2009)
  • Author(s): Shimada K, Isoda H, Okada T, Maetani Y, Arizono S, Hirokawa Y, Kamae T, Togashi K
  • Journal Title: Eur J Radiology 70 Pages: 111-117
  • Peer Reviewed
• [Presentation] Multichannel Radiofrequency Excitation Upper Abdominal MR Imaging at 3 T : Challenged and Their Solutions (2011)
  • Author(s): Shimizu H, Isoda H, Kawahara S, Shimada K, Shibata T, Togashi K.
  • Organizer: 97^th RSNA
  • Place of Presentation: Chicago
• [Presentation] Non-contrast-enhanced Hepatic MR Angiography with Time Spatial Labeling Inversion Pulse (2011)
  • Author(s): Isoda H, Okada T, Shimada K, Kawahara S, Shimizu H, Togashi K
  • Organizer: 19^th ISMRM
  • Place of Presentation: Montreol
• [Presentation] Non-contrast-enhanced Hepatic MR Angiography with Time Spatial Labeling Inversion Pulse (2011)
  • Author(s): Isoda H, Okada T, Shimada K, Kawahara S, Shimizu H, Togashi K
  • Organizer: 19^<th> ISMRM 2011
  • Place of Presentation: モントリオール(カナダ)
• [Presentation] Multichannel Radiofrequency Excitation Upper Abdominal MR Imaging at 3 T : Challenged and Their Solutions (2011)
  • Author(s): Shimizu H, Isoda H, Kawahara S, Shimada K, Shibata T, Togashi K
  • Organizer: 97^<th> RSNA 2011
  • Place of Presentation: シカゴ(アメリカ)
• [Presentation] PROPELLER(BLADE) Technique to Upper Abdominal MR Imaging (2010)
  • Author(s): Isoda H, Hirokawa Y, Shimada K, Arizono S, Shibata T, Togashi K
  • Organizer: ECR
  • Place of Presentation: Wien
• [Presentation] Non-contrast-enhanced hepatic MR arteriography with two-dimensional parallel imaging and short tau inversion recovery methods to shorten acquisition time without image quality deterioration (2010)
  • Author(s): Isoda H, Shimada K, Arizono S, Hirokawa Y, Shibata T, Togashi K
  • Organizer: 18^th ISMRM
  • Place of Presentation: Stockholm
• [Presentation] MR Imaging Using Propeller(Blade) Technique at Upper Abdomen : Principles, Scanning Technique, Image Quality, and Clinical Experience (2010)
  • Author(s): Isoda H, Hirokawa Y, Shimada K, Arizono S, Shibata T, Togashi K
  • Organizer: 96^th RSNA
  • Place of Presentation: Chicago
• [Presentation] 腹部領域における3テスラシステムの臨床応用と展望 (2010)
  • Author(s): 磯田裕義
  • Organizer: 第69回日本医学放射線学会総会産学連携セミナー
  • Place of Presentation: 横浜
• [Presentation] CT/MRIを用いた門脈・肝静脈画像の実際 (2010)
  • Author(s): 磯田裕義
  • Organizer: 第46回肝癌研究会ランチョンセミナー
  • Place of Presentation: 大阪
• [Presentation] Non-contrast-enhanced hepatic MR arteriography with two-dimensional parallel imaging and short tau inversion recovery methods to shorten acquisition time without image quality deterioration. (2010)
  • Author(s): Isoda H, Shimada K, Arizono S, Hirokawa Y, Shibata T, Togashi K.
  • Organizer: 18^<th> ISMRM
  • Place of Presentation: Stockholm
• [Presentation] 腹部領域における3テスラシステムの臨床応用と展望 (2010)
  • Author(s): 磯田裕義
  • Organizer: 第69回日本医学放射線学会総会産学連携セミナー
  • Place of Presentation: 横浜(招待講演)
• [Presentation] CT/MRIを用いた門脈・肝静脈・画像の実際 (2010)
  • Author(s): 磯田裕義
  • Organizer: 第46回肝癌研究会ランチョンセミナー
  • Place of Presentation: 大阪(招待講演)
• [Presentation] MAGNETOM Skyraが示す3T MRIの方向性 (2010)
  • Author(s): 磯田裕義
  • Organizer: 第38回日本磁気共鳴医学会大会ランチョンセミナー
  • Place of Presentation: つくば(招待講演)
• [Presentation] 非造影血管描出法の進歩と高磁場への適用検討 : 腹部領域における選択的血管描出能を中心に (2009)
  • Author(s): 磯田裕義
  • Organizer: 第45回日本医学放射線学会秋季臨床大会ランチョンセミナー
  • Place of Presentation: 和歌山
  • Year and Date: 2009-10-30
• [Presentation] 非造影血管描出法の進歩と高磁場への適用検討:腹部領域における選択的血管描出能を中心に (2009)
  • Author(s): 磯田裕義
  • Organizer: 第45回日本医学放射線学会秋季臨床大会ランチョンセミナー
  • Place of Presentation: 和歌山
• [Presentation] 非造影血管描出法の進歩と高磁場への適用検討:腹部領域における選択的血管描出能を中心に (2009)
  • Author(s): 磯田裕義
  • Organizer: 東芝ベストイメージ
  • Place of Presentation: 東京