Quantification and optimization of X-ray dose in chest CT

• Project/Area Number: 21591559
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: KUBO Takeshi 京都大学, 医学研究科, 助教 (20464216)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: エックス線 / CT / X線線量低減 / 自動線量調節機構

Research Abstract

Reduction in radiation dose in chest CT can be attained by modifying image production methods and raising noise indexes without collateral reduction of readers' effectiveness in lesion detection. Radiation dose reduction in CT is expected to lead to safer CT examination or makes dynamic imaging possible, allowing analysis of functional anatomy in patients with pulmonary diseases.

Research Products

• [Journal Article] Association between vascular-poor area of primary tumors and epidermal growth factor receptor gene status in advanced lung adenocarcinoma (2012)
  • Author(s): Togashi Y, Kubo T, et al.
  • Journal Title: Med Oncol Volume: なし Issue: 5 Pages: 3169-3175
  • DOI: 10.1007/s12032-012-0235-7
  • Peer Reviewed
• [Journal Article] Impact of COPD Exacerbations on Osteoporosis Assessed by Chest CT Scan (2012)
  • Author(s): Kiyokawa H, Muro S, Oguma T, Sato S, Tanabe N, Takahashi T, Kudo M, Kinose D, Kondoh H, Kubo T, Hoshino Y, Ogawa E, Hirai T, Mishima M
  • Journal Title: Epub Volume: 9(3) Issue: 3 Pages: 235-42
  • DOI: 10.3109/15412555.2011.650243
  • NAID: 120004873856
  • Peer Reviewed
• [Journal Article] ssociation of diffuse, random pulmonary metastases, including miliary metastases, with epidermal growth factor receptor mutations in lung adenocarcinoma (2011)
  • Author(s): Togashi Y, Kubo T, et al.
  • Journal Title: Cancer Volume: 217 Issue: 4 Pages: 819-825
  • DOI: 10.1002/cncr.25618
  • Peer Reviewed
• [Journal Article] HRCT features of interstitial lung disease in dermatomyositis with anti-CADM-140 antibody (2011)
  • Author(s): Tanizawa K, Kubo T, et al.
  • Journal Title: Respiratory Medicine Volume: 105 Issue: 9 Pages: 1380-1387
  • DOI: 10.1016/j.rmed.2011.05.006
  • NAID: 120003290277
  • Peer Reviewed
• [Journal Article] Development and evaluation of a low-cost and high-capacity DICOM image data storage system for research (2011)
  • Author(s): Yakami M, Kubo T, et al.
  • Journal Title: ournal of Digital Imaging Volume: 24 Issue: 2 Pages: 190-195
  • DOI: 10.1007/s10278-009-9267-8
  • Peer Reviewed
• [Journal Article] 多発結節影 (2010)
  • Author(s): 久保武
  • Journal Title: 呼吸 Volume: 29 Pages: 605-611
  • Peer Reviewed
• [Journal Article] Extraction of tube current values from DICOM CT images for patient dose estimation (2010)
  • Author(s): Lin PJ, Kubo T, Krishnapillai R.
  • Journal Title: Med Phys Volume: 37(6) Issue: 6Part1 Pages: 2951-5
  • DOI: 10.1118/1.3429054
  • Peer Reviewed
• [Journal Article] Extraction of Tube Current Values From DICOM CT Images For Patient Dose Estimation
  • Author(s): Lin Pei-Jan Paul、Takeshi Kubo
  • Journal Title: Medical Physics (掲載決定)
  • Peer Reviewed
• [Presentation] Kubo T 4-dimentional imaging of the central airway using a low dose technique : Initial experience with 320-row multidetector CT (2012)
  • Author(s): Sakamoto R
  • Organizer: Joint Meeting combining The 3rd meeting of the Japanese Society of Pulmonary Functional Imaging and 5th International Workshop of Pulmonary
  • Place of Presentation: Awaji, Hyogo, Japan
  • Year and Date: 2012-12-11
• [Presentation] 孤立性結節に伴う数値特徴量利用の試み (2012)
  • Author(s): 酒井晃二、久保武, ほか
  • Organizer: 第4回呼吸機能イメージング研究会学術集会
  • Place of Presentation: 滋賀県大津市
  • Year and Date: 2012-02-10
• [Presentation] A Low Dose CT Lung Screening Method for Smoking-related Thoracic Abnormalities Using 3D Automatic Exposure Control : Diagnostic Capability and Effectiveness in Radiation Dose Reduction (2011)
  • Author(s): Kubo T.
  • Organizer: Joint Meeting combining The 3rd meeting of the Japanese Society of Pulmonary Functional Imaging and 5th International Workshop of Pulmonary
  • Place of Presentation: Awaji, Hyogo, Japan
  • Year and Date: 2011-12-11
• [Presentation] 4-dimentional imaging of the central airway using a low dose technique : Initial experience with 320-row multidetector CT (2011)
  • Author(s): Ryo Sakamoto
  • Organizer: Joint Meeting combining The 3rd meeting of the Japanese Society of Pulmonary Functional Imaging and 5th International Workshop of Pulmonary Functional Imaging
  • Place of Presentation: 淡路夢舞台国際会議場(兵庫県淡路市)
  • Year and Date: 2011-01-29
• [Presentation] A Low Dose CT Lung Screening Method for Smoking-related Thoracic Abnormalities Using 3D Automatic Exposure Control : Diagnostic Capability and Effectiveness in Radiation Dose Reduction (2011)
  • Author(s): Takeshi Kubo
  • Organizer: Joint Meeting combining The 3rd meeting of the Japanese Society of Pulmonary Functional Imaging and 5th International Workshop of Pulmonary Functional Imaging
  • Place of Presentation: 淡路夢舞台国際会議場(兵庫県淡路市)
  • Year and Date: 2011-01-29
• [Presentation] Low Dose CT Lung Screening Method for Smoking-related Thoracic Abnormalities Using 3D Automatic Exposure Control : Diagnostic Capability and Effectiveness in Radiation Dose Reduction (2010)
  • Author(s): Kubo T
  • Organizer: Radiological Society of North America
  • Place of Presentation: Chicago MA, USA
  • Year and Date: 2010-04-08
• [Presentation] 結節性病変検出能における胸部CT画質の影響-シミュレーション画像を用いた検討 (2010)
  • Author(s): 久保武
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2010-04-08
• [Presentation] 結節性病変検出能における胸部CT画質の影響・シミュレーション画像を用いた検討 (2010)
  • Author(s): 久保武
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜(横浜市)
  • Year and Date: 2010-04-08
• [Presentation] A Low Dose CT Lung Screening Method for Smoking-related Thoracic Abnormalities Using 3D Automatic Exposure Control : Diagnostic Capability and Effectiveness in Radiation Dose Reduction (2010)
  • Author(s): Takeshi Kubo
  • Organizer: Radiological Society of North America
  • Place of Presentation: McCormick Place(アメリカ合衆国、シカゴ)
  • Year and Date: 2010-04-08
• [Presentation] Nodule detection capability of simulated reduced dose chest CT and standard dose CT using (2010)
  • Author(s): Kubo T
  • Organizer: automatic exposure control system
  • Place of Presentation: Austria Center Vienna
  • Year and Date: 2010-03-04
• [Presentation] Nodule detection capability of simulated reduced dose chest CT and standard dose CT using automatic exposure control system (2010)
  • Author(s): Takeshi Kubo
  • Organizer: European Congress of Radiology
  • Place of Presentation: Austria Center Vienna (ウィーン、オーストリア)
  • Year and Date: 2010-03-04
• [Presentation] 胸部CTにおける軟部組織画像と肺野画像統合の可能性-画像フィルタ使用による検討 (2009)
  • Author(s): 久保武
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2009-04-18
• [Presentation] 胸部CTにおける軟部組織画像と肺野画像統合可能性-画像フィルタ使用による検討 (2009)
  • Author(s): 久保武
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: バシフィコ横浜(横浜市)
  • Year and Date: 2009-04-18
• [Book] ガイドライン外来診療2011別冊CT診断基礎・臨床2011年日経メディカル開発 (2011)
  • Author(s): 久保武
  • Total Pages: 25
• [Book] 胸部のCT第3版第14章まれなびまん性肺疾患 (2011)
  • Author(s): 梅岡成章、久保武, ほか
  • Total Pages: 25
  • Publisher: メディカルサイエンスインターナショナル
• [Book] ガイドライン外来診療2011別冊資料CT診断基礎・臨床 (2011)
  • Author(s): 久保武
  • Total Pages: 25
  • Publisher: 日経メディカル開発
• [Book] ガイドライン外来診療2010別冊CT診断基礎・臨床 胸部編 (2010)
  • Author(s): 久保武
  • Total Pages: 25
  • Publisher: 日経メディカル開発
• [Book] ガイドライン外来診療2010別冊CT診断基礎・臨床2010年日経メ
  • Author(s): 久保武