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Evaluation of iodine concentration in areas with ground glass attenuation of the lung by contrast-mapping images obtained with dual-energy CT

Research Project

Project/Area Number 21591574
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionNagoya City University

Principal Investigator

HARA Masaki  名古屋市立大学, 大学院・医学研究科, 准教授 (50244562)

Co-Investigator(Kenkyū-buntansha) SHIBAMOTO Yuta  名古屋市立大学, 大学院・医学研究科, 教授 (20144719)
SASAKI Shigeru  名古屋市立大学, 大学院・医学研究科, 助教 (80444959)
SHIRAKI Norio  名古屋市立大学, 大学院・医学研究科, 助教 (50326154)
OZAWA Yoshiyuki  名古屋市立大学, 大学院・医学研究科, 助教 (90569005)
KOBAYASHI Susumu  名古屋市立大学, 大学院・医学研究科, 助教 (70596949)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsdual energy CT / 造影CT / perfusion CT / ground-glass attenuation / diffuse lung disease
Research Abstract

Using a dual-energy(80 and 140 kVp) mode of a dual-source CT scanner, we confirmed that Iodine concentration in areas with ground-glass attenuation(GGA ;-100 to-700 Hounsfield Unit) could be measured on phantom examination. As a clinical study this method was applied to pre-operative lung cancer patients with or without diffuse lung diseases including a finding of diffuse GGA. The Iodine concentration within the areas of diffuse GGA could also be evaluated and we found a few unknown and interesting CT findings of Iodine concentration of diffuse pulmonary GGA.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (9 results)

All 2012 2011 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (7 results)

  • [Journal Article] Can dual-energyCT evaluate contrast enhancemen of ground-glass attenuation? Phantom and preliminary clinical studies2011

    • Author(s)
      河合辰哉、原眞咲、芝本雄太、荒川利直、永井圭一、大橋一也
    • Journal Title

      Academic Radiology

      Volume: 18巻 Issue: 6 Pages: 682-689

    • DOI

      10.1016/j.acra.2010.12.014

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Can dual-energy CT evaluate contrast enhancement of ground-glass attenuation? Phantom and preliminary clinical studies.2011

    • Author(s)
      河合辰哉, 原眞咲, 芝本雄太, 他
    • Journal Title

      Academic Radiology

      Volume: (Epub 8 March Ahead of print)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Evaluation of iodine concentration in normal lung and diffuse lung diseases by contrast-mapping images obtained using dual-energy CTtechnique2012

    • Author(s)
      小林晋、原眞咲、荒川利直、河合辰哉、小澤良之、芝本雄太
    • Organizer
      24^<nd> European Congress ofRadiology 2012、Scientific Exhibit
    • Place of Presentation
      Vienna、Austria
    • Related Report
      2011 Final Research Report
  • [Presentation] Evaluation of iodine concentration in normal lung and diffuse lung diseases by contrast-mapping images obtained using dual-energy CT technique2012

    • Author(s)
      小林晋, 原眞咲, 荒川利直, 他
    • Organizer
      24^<nd> European congress of radiology 2012
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2011 Annual Research Report
  • [Presentation] Most optimum display settings (width and level) of dual energy perfusion CT for diagnosing pulmonary embolism.2011

    • Author(s)
      鈴木智博, 原眞咲, 芝本雄太, 他
    • Organizer
      The 5th International Workshop of Pulmonary Funct Tonal Imaging
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県)
    • Year and Date
      2011-01-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Most optimum display settings(width and level) of dual energy perfusion CT for diagnosing pulmonaryembolism2011

    • Author(s)
      鈴木智博、原眞咲、中川基生、小澤良之、櫻井圭太、芝本雄太
    • Organizer
      5th InternationalWorkshop of Pulmonary Functional Imaging、Poster exhibit
    • Place of Presentation
      Hyogo, Japan
    • Related Report
      2011 Final Research Report
  • [Presentation] Can Dual-Energy CT Evaluate Contrast Enhancement of Ground-Glass Attenuation? -A Phantom Study-2010

    • Author(s)
      河合辰哉, 原眞咲, 芝本雄太, 他
    • Organizer
      European congress of radiology 2010
    • Place of Presentation
      Austria Center Vienna
    • Year and Date
      2010-03-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] Can dual-energy CT evaluate contrast enhancement of ground-glass attenuation?-A phantom study-2010

    • Author(s)
      河合辰哉、原眞咲、小澤良之、中川基生、芝本雄太
    • Organizer
      22^<nd> European Congress of Radiology2010、Scientific Session
    • Place of Presentation
      Vienna、Austria
    • Related Report
      2011 Final Research Report
  • [Presentation] Dual-energy CTを用いた陰性吸収値病変における造影効果の定量的評価2009

    • Author(s)
      河合辰哉, 原眞咲, 芝本雄太, 他
    • Organizer
      第146回日本医学放射線学会中部地方会
    • Place of Presentation
      アクトシティ浜松 コングレスセンター(静岡県)
    • Year and Date
      2009-06-27
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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