Establishment of MRI-guided planning in high-dose-rate brachytherapyof prostate cancer
| Project/Area Number |
21591582
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
ITO Katsuyoshi 川崎医科大学, 医学部, 教授 (00274168)
YAMASHITA Takenori 川崎医科大学, 医学部, 講師 (30299200)
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| Co-Investigator(Renkei-kenkyūsha) |
SONE Teruki 川崎医科大学, 医学部, 教授 (90179383)
JO Yoshimasa 川崎医科大学, 医学部, 講師 (40319968)
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| Project Period (FY) |
2009 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 前立腺癌 / 核磁気共鳴画像 / MRI |
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| Research Abstract |
In our studies using multiparametric prostate MR imaging, the tumor detectability of prostate cancer before radiotherapy (high-dose-rate brachytherapy (HDR-BT)), the change of MR findings after HDR-BT and the detectability of locally recurrent prostate cancer after HDR-BT were investigated. As the results, multiparametric MRI showed the high detectability for a significant cancer with the treatment intervention. In addition, after radiotherapy, the MR findings in T2-weighted imaging such as zonal indistinctness and diffuse reduction of the signal intensity in the gland interfered with the diagnosis of recurrent tumor. Furthermore, our results indicated that a multiparametric MRI protocol that includes diffusion-weighted imaging provides a sensitive method to detect local recurrence after HDR brachytherapy.
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Report
(5 results)
Research Products
(20 results)
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[Presentation] MR Diagnosis in Prostate Cancer Detection: The Spectrum of Imaging Findings on Pre and Post Therapy2010
Author(s)
Tsutomu Tamada, Katsuyoshi Ito, Hiroki Higashi, Daigo Tanimoto, Naoto Egashira, Fuyuki Tanaka, Tomohiro Sato, Akihiko Kanki, Atsushi Higaki, Teruyuki Torigoe, and Yasufumi Noda.
Organizer
RSNA
Place of Presentation
Chicago アメリカ
Related Report
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