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Radifrequency ablation for resectable colorectal lung metastasis: A prospective clinical trial

Research Project

Project/Area Number 21591595
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionMie University

Principal Investigator

YAMAKADO Koichiro  三重大学, 医学部附属病院, 准教授 (20263022)

Co-Investigator(Kenkyū-buntansha) YASUHIRO Inoue  三重大学, 医学部附属病院, 講師 (20324535)
MOTOSHI Takao  三重大学, 医学部附属病院, 准教授 (30263007)
HARUYUKI Takaki  三重大学, 医学部, 医員 (30378377)
Project Period (FY) 2009-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords大腸癌 / 転移性肺がん / ラジオ波焼灼術 / 転移性肺癌 / ラジオ波凝固療法 / 肺転移
Research Abstract

This prospective clinical trial was undertaken to evaluate the clinical utility of lung radiofrequency ablation (RFA) used for the treatment of resectable colorectal ling metastases. The primary endpoint of this study was the 3-year overall survival. Seventy patients were enrolled in April 2014. The results will be opened in 2019.

Report

(6 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (43 results)

All 2014 2013 2012 2011 2010 2009

All Journal Article (29 results) (of which Peer Reviewed: 15 results) Presentation (12 results) (of which Invited: 1 results) Book (2 results)

  • [Journal Article] Radiofrequency ablation versus radical nephrectomy:clinical outcomes for stage T1b renal cell carcinoma2014

    • Author(s)
      Takaki H, Soga N, Kanda H, Nakatsuka A, Uraki J, Fujimori M, Yamanaka T, Hasegawa T, Arima K, Sugimura Y, Sakuma H, Yamakado K
    • Journal Title

      Radiology

      Volume: 270(1)(Epub 2013 Oct 28. PMID:23925272, PubMed - indexed for MEDLINE) Issue: 1 Pages: 292-9

    • DOI

      10.1148/radiol.13130221

    • Related Report
      2013 Final Research Report
  • [Journal Article] Limited expression of cancer-testis antigens in renal cell carcinoma patients2013

    • Author(s)
      Soga N, Hori Y, Yamakado K, Ikeda H, Imai N, Kageyama S, Nakase K, Yuta A, Hayashi N, Shiku H, Sugimura Y
    • Journal Title

      Mol Clin Oncol

      Volume: 1(2), (Epub, PMID:24649170) Pages: 326-330

    • Related Report
      2013 Final Research Report
  • [Journal Article] Radiofrequency ablation for the treatment of recurrent bone and soft-tissue sarcomas in non-surgical candidates2013

    • Author(s)
      Yamakado K, Matsumine A, Nakamura T, Nakatsuka A, Takaki H, Matsubara T, Asanuma K, Sudo A, Sugimura Y, Sakuma H
    • Journal Title

      Int J Clin Oncol

      Volume: (Epub ahead of print, PMID:24287606, PubMed - as supplied by publisher)

    • Related Report
      2013 Final Research Report
  • [Journal Article] Rib fractures after radiofrequency and microwave ablation of lung tumors2013

    • Author(s)
      Yamakado K, Takaki H, Nakatsuka A
    • Journal Title

      Radiology

      Volume: 269(3) Issue: 3 Pages: 946-946

    • DOI

      10.1148/radiol.13131612

    • Related Report
      2013 Final Research Report
  • [Journal Article] Radiofrequency Ablation After Arterial Injection of Miriplatin-Iodized Oil Suspension Into Swine Liver:Ablative Zone Size and Tissue Platinum Concentration2013

    • Author(s)
      Yamanaka T, Takaki H, Nakatsuka A, Uchida K, Junji U, Fujimori M, Hasegawa T, Yoneda M, Shiraishi T, Sakuma H, Yamakado K
    • Journal Title

      Cardiovasc Intervent Radiol

      Volume: (Epub ahead of print, PMID:24232037, PubMed - as supplied by publisher)

    • Related Report
      2013 Final Research Report
  • [Journal Article] Clinical significance of radiofrequency ablation and metastasectomy in elderly patients with lung metastases from musculoskeletal sarcomas2013

    • Author(s)
      Nakamura T, Matsumine A, Yamakado K, Takao M, Uchida A, Sudo A
    • Journal Title

      J Cancer Res Ther

      Volume: 9(2)(PMID:23771362, PubMed - indexed for MEDLINE) Issue: 2 Pages: 219-23

    • DOI

      10.4103/0973-1482.113358

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of 18F-FDG-PET/CT on treatment strategy in colorectal cancer lung metastasis before lung radiofrequency ablation2013

    • Author(s)
      Kodama H, Yamakado K, Takaki H, Suzawa N, Yamada T, Takeda K
    • Journal Title

      Nucl Med Commun

      Volume: 34(7)(PMID:23636294, PubMed - indexed for MEDLINE) Issue: 7 Pages: 689-93

    • DOI

      10.1097/mnm.0b013e328361cd28

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Response to "the use of radiofrequency ablation in gastrointestinal stromal tumor"2013

    • Author(s)
      Yamanaka T, Takaki H, Nakatsuka A, Uraki J, Fujimori M, Hasegawa T, Sakuma H, Yamakado K
    • Journal Title

      J Vasc Interv Radiol

      Volume: 24(5), (PMID:23622045) Issue: 5 Pages: 751-751

    • DOI

      10.1016/j.jvir.2013.02.025

    • Related Report
      2013 Final Research Report
  • [Journal Article] Outcome for pulmonary metastases from malignant osteogenic and soft tissue sarcomas2013

    • Author(s)
      Tempaku H, Takao M, Shimamoto A, Murashima S, Yamakado K, Nakamura T, Matsumine A, Shimpo H
    • Journal Title

      Kyobu Geka

      Volume: 66(4), (PMID:23575184, PubMed - indexed for MEDLINE) Pages: 311-4

    • NAID

      40019637420

    • Related Report
      2013 Final Research Report
  • [Journal Article] Frequency of and risk factors for complications after liver radiofrequency ablation under CT fluoroscopic guidance in 1500 sessions:single-center experience2013

    • Author(s)
      Takaki H, Yamakado K, Nakatsuka A, Yamada T, Shiraki K, Takei Y, Takeda K
    • Journal Title

      AJR Am J Roentgenol

      Volume: 200(3), (PMID:23436859, PubMed - indexed for MEDLINE) Issue: 3 Pages: 658-64

    • DOI

      10.2214/ajr.12.8691

    • Related Report
      2013 Final Research Report
  • [Journal Article] Detection of local tumor progression by (18)F-FDG PET/CT following lung radiofrequency ablation:PET versus CT2013

    • Author(s)
      Suzawa N, Yamakado K, Takao M, Taguchi O, Yamada T, Takeda K
    • Journal Title

      Clin Nucl Med

      Volume: 38(4), (PMID:23429399, PubMed - indexed for MEDLINE) Issue: 4 Pages: 166-170

    • DOI

      10.1097/rlu.0b013e31828166f6

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Survival with up to 10-year follow-up after combination therapy of chemoembolization and radiofrequency ablation for the treatment of hepatocellular carcinoma:single-center experience2013

    • Author(s)
      Fujimori M, Takaki H, Nakatsuka A, Uraki J, Yamanaka T, Hasegawa T, Shiraki K, Takei Y, Sakuma H, Yamakado K
    • Journal Title

      J Vasc Interv Radiol

      Volume: 24(5), (Epub 2013 Feb 18. PMID:23428356) Issue: 5 Pages: 655-66

    • DOI

      10.1016/j.jvir.2012.12.009

    • Related Report
      2013 Final Research Report
  • [Journal Article] Hyaluronic acid gel injection to prevent thermal injury of adjacent gastrointestinal tract during percutaneous liver radiofrequency ablation2013

    • Author(s)
      Hasegawa T, Takaki H, Miyagi H, Nakatsuka A, Uraki J, Yamanaka T, Fujimori M, Sakuma H, Yamakado K
    • Journal Title

      Cardiovasc Intervent Radiol

      Volume: 36(4), (Epub 2013 Jan 25. PMID:23354960, PubMed - indexed for MEDLINE) Issue: 4 Pages: 1144-6

    • DOI

      10.1007/s00270-013-0546-x

    • Related Report
      2013 Final Research Report
  • [Journal Article] Radiofrequency ablation for liver metastasis from gastrointestinal stromal tumor2013

    • Author(s)
      Yamanaka T, Takaki H, Nakatsuka A, Uraki J, Fujimori M, Hasegawa T, Sakuma H, Yamakado K
    • Journal Title

      J Vasc Interv Radiol

      Volume: 24(3), (PMID:23352855, PubMed - indexed for MEDLINE) Issue: 3 Pages: 341-6

    • DOI

      10.1016/j.jvir.2012.11.021

    • Related Report
      2013 Final Research Report
  • [Journal Article] Renal cell carcinoma:radiofrequency ablation with a multiple-electrode switching system--a phase II clinical study2013

    • Author(s)
      Takaki H, Nakatsuka A, Uraki J, Yamanaka T, Fujimori M, Hasegawa T, Arima K, Sugimura Y, Yamakado K
    • Journal Title

      Radiology

      Volume: 267(1), (PMID:23315660) Issue: 1 Pages: 285-92

    • DOI

      10.1148/radiol.12121070

    • Related Report
      2013 Final Research Report
  • [Journal Article] CT-fluoroscopy in chest interventional radiology: sliding scale of imaging parameters based on radiation exposure dose and factors increasing radiation exposure dose.2013

    • Author(s)
      Yamao Y, Yamakado K, Takaki H, Yamada T, Kodama H, Nagasawa N, Nakatsuka A, Uraki J, Takeda K.
    • Journal Title

      Clin Radiol

      Volume: 68 Issue: 2 Pages: 162-166

    • DOI

      10.1016/j.crad.2012.05.020

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Outcome for pulmonary metastases from malignant osteogenic and soft tissue sarcomas].2013

    • Author(s)
      Tempaku H, Takao M, Shimamoto A, Murashima S, Yamakado K, Nakamura T, Matsumine A, Shimpo H.
    • Journal Title

      Kyobu Geka

      Volume: 66 Pages: 311-314

    • NAID

      40019637420

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combination therapy of chemoembolization and radiofrequency ablation for the treatment of hepatocellular carcinoma in the caudate lobe2012

    • Author(s)
      Fujimori M, Takaki H, Nakatsuka A, Uraki J, Yamanaka T, Hasegawa T, Shiraki K, Takei Y, Yamakado K
    • Journal Title

      J Vasc Interv Radiol

      Volume: 23(12), (PMID:23177108) Issue: 12 Pages: 1622-8

    • DOI

      10.1016/j.jvir.2012.09.005

    • Related Report
      2013 Final Research Report
  • [Journal Article] Ablative zone size created by radiofrequency ablation with and without chemoembolization in small hepatocellular carcinomas.2012

    • Author(s)
      Takashi Yamanaka
    • Journal Title

      Japanese journal of RAdiology

      Volume: 30 Issue: 7 Pages: 553-559

    • DOI

      10.1007/s11604-012-0087-2

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Incidence and cause of hypertension during adrenal radiofrequency ablation.2012

    • Author(s)
      Koichiro Yamakado
    • Journal Title

      Cardiovascular and interventional radiology

      Volume: 35 Issue: 6 Pages: 1422-1427

    • DOI

      10.1007/s00270-012-0348-6

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Adrenal radiofrequency ablation in swine : change in blood pressure and histopathologic analysis2011

    • Author(s)
      Yamakado K, 他
    • Journal Title

      Cardiovasc Intervent Radiol

      Volume: 34 Pages: 839-844

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Management of renal tumors in Von Hippel-Lindau disease by percutaneous CT fluoroscopic guided radiofrequency ablation : preliminary results2011

    • Author(s)
      Iwamoto Y, Kanda H, Yamakado K, 他
    • Journal Title

      Fam Cancer

      Volume: 10 Pages: 529-534

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Percutaneous radiofrequency ablation for pulmonary metastases from hepatocellular carcinoma : results of a multicenter study in Japan2011

    • Author(s)
      Hiraki T, Yamakado K, 他
    • Journal Title

      J Vase Interv Radiol

      Volume: 22 Pages: 741-748

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimal scan parameters for CT fluoroscopy in lung interventional radiologic procedures : relationship between radiation dose and image quality.2010

    • Author(s)
      Yamao Y, Yamakado K, 他
    • Journal Title

      Radiology

      Volume: 255(1): Pages: 233-241

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Midterm results of radiofrequency ablation versus nephrectomy for T1a renal cell carcinoma.2010

    • Author(s)
      Takaki H, Yamakado K, 他
    • Journal Title

      Jpn J Radiol

      Volume: 28 Pages: 460-468

    • NAID

      50007723506

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical significance of tumor markers in detection of recurrent hepatocellular carcinoma after radiofrequency ablation.2010

    • Author(s)
      Beppu T, Yamakado K, 他
    • Journal Title

      Int J Mol Med.

      Volume: 26 Pages: 425-433

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adrenal metastasis from hepatocellular carcinoma: radiofrequency ablation combined with adrenal arterial chemoembolization in six patients2009

    • Author(s)
      Yamakado K, Takaki H, 他5名
    • Journal Title

      Am J Roentgenol. 192

      Pages: 300-305

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Long-term results of radiofrequency ablation in colorectal lung metastases : single center experience2009

    • Author(s)
      Yamakado K, Inoue Y, Takao M, Takaki H, 他6名
    • Journal Title

      Oncol Rep. 22

      Pages: 885-891

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subphrenic versus nonsubphrenic hepatocellular carcinoma : combined therapy with chemoembolization and radiofrequency ablation2009

    • Author(s)
      Yamakado K, Takaki H, 他6名
    • Journal Title

      Am J Roentgenol. 194

      Pages: 530-535

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 肺腫瘍に対するRFA2013

    • Author(s)
      山門亨一郎
    • Organizer
      2013ミッドウインターセミナー
    • Place of Presentation
      福岡
    • Related Report
      2013 Final Research Report
  • [Presentation] クッシング症候群に対するIVR:RFA2013

    • Author(s)
      山門亨一郎
    • Organizer
      第86回日本内分泌学会
    • Place of Presentation
      仙台
    • Related Report
      2013 Final Research Report
  • [Presentation] 肺RFA2013

    • Author(s)
      山門亨一郎
    • Organizer
      ミッドウィンターセミナー
    • Place of Presentation
      神戸
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Combination of TACE and RFA2012

    • Author(s)
      Yamakado K
    • Organizer
      APCCVIR
    • Place of Presentation
      Kobe
    • Related Report
      2013 Final Research Report
  • [Presentation] この症例をどう治療するか?消化管に近接した肝被膜下HCC症例2012

    • Author(s)
      山門亨一郎
    • Organizer
      第7回肝癌治療シミュレーション研究会
    • Place of Presentation
      熊本
    • Related Report
      2013 Final Research Report
  • [Presentation] 肝RFA-最近の進歩2011

    • Author(s)
      山門亨一郎
    • Organizer
      日本医学放射線学会秋季大会
    • Place of Presentation
      山口県下関市(招待講演)
    • Year and Date
      2011-10-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Radiofrequency ablation for lung tumors2010

    • Author(s)
      Yamakado K
    • Organizer
      Radiology Society Republic of China
    • Place of Presentation
      台湾、台北(招待講演)
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] Radiofrequency ablation for lung metastasis2010

    • Author(s)
      Yamakado K
    • Organizer
      第96回北米放射線学会(シカゴ)
    • Place of Presentation
      米国、シカゴ(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Presentation of a scientific paper in English : A nonnative English speaker's experience2010

    • Author(s)
      Yamakado K
    • Organizer
      第4回Society of gastrointestinal intervention
    • Place of Presentation
      韓国、ソウル(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] RFA装置2010

    • Author(s)
      山門亨一郎
    • Organizer
      第39回日本IVR学会総会
    • Place of Presentation
      東京(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] シンポするアブレーション:その他のRFA2010

    • Author(s)
      山門亨一郎
    • Organizer
      第39回日本IVR学会総会
    • Place of Presentation
      東京(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Therapeutic strategy for stage IA non-small cell lung cancer : Radiofrequency ablation2009

    • Author(s)
      山門亨一郎
    • Organizer
      50th JSLC/IASLC joint workshop on Advances in Lung Cancer
    • Place of Presentation
      東京
    • Year and Date
      2009-11-14
    • Related Report
      2009 Annual Research Report
  • [Book] IVRマニュアル第2版:ラジオ波凝固療法(腎)2011

    • Author(s)
      栗林幸夫、増田裕、似鳥俊明、中村健治、吉岡哲也、廣田省三、早川克己、橋本統、福田哲也、東浦渉、田中良一、高山勝年、吉川公彦、石口恒男、杉本幸司、南口博紀、佐藤守男、田島康之、加地辰美、三村秀文、金澤右、古井滋、神武裕、岩田美郎、齋藤拓郎、成松芳明、古川顕、井隼孝司、西田典史、勝盛哲也、大須賀慶悟、坂口浩、羽室雅夫、宮山士朗、山上卓士、佐藤修、藤田正人、井上祐喜、今井茂樹、阿部等思、山本聡、山下寛高、西巻博、磯部義憲、橋本一樹、淀野啓、松岡利幸、堺幸正。前田弘彰、荒井保明、松尾国弘、松本真一、興梠征典、掛田伸吾、井上正義、森田壮二郎、齋藤博哉、山本孝信、小川晋久、滝澤謙治、田頭周一、神納敏夫、穴井洋、山門亨一郎、谷川昇、最上拓児、原田潤太、中塚誠之、蘆田浩、古市欣也、新槙剛、熊野玲子、山内栄五郎、高菜健寛、稲葉吉隆、前田宗宏、下山恵司、丹呉惠理、野宮香織、松田麻衣子、米山美和子、も井山萬秀、市田隆雄、鈴木滋、米虫敦、水沼仁孝.
    • Publisher
      医学書院
    • Related Report
      2013 Final Research Report
  • [Book] ガイドラインサポートハンドブック 大腸癌 大腸癌治療ガイドライン2009年版2009

    • Author(s)
      山門亨一郎
    • Total Pages
      239
    • Publisher
      医薬ジャーナル
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2019-07-29  

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