| Project/Area Number |
21591662
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
KASUYA Hideki 名古屋大学, 大学院・医学系研究科, 准教授 (00402636)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAO Akimasa 名古屋大学, 大学院・医学系研究科, 教授 (70164754)
TAKEDA Shin 名古屋大学, 大学院・医学系研究科, 講師 (20314015)
SUGIMOTO Hiroyuki 名古屋大学, 医学部附属病院, 助教 (20437007)
NOMOTO Shuji 名古屋大学, 医学部附属病院, 病院講師 (40300967)
中尾 昭公 名古屋大学, 医学系研究科, 教授 (70167542)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 癌 / ウイルス / 転移性肝癌 / 腫瘍溶解性ウイルス / HF10 / B16ova / 腫瘍免疫 / ヘルペスウイルス / R3616 / hrR3 / CD8 |
|---|
| Research Abstract |
We have researched new methodology using anti tumor lymphocyte for delivering oncolytic virus R3616. Adsorbed R3616 on tumor antigen specific lymphocyte reached target tumor, and infected to tumor cells. This anti tumor effect has statistic different from adsorbed R3616 on tumor antigen non-specific lymphocyte. We acquired precious basic data for clinical trial.
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