Project/Area Number |
21591826
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Thoracic surgery
|
Research Institution | Tokyo Medical University |
Principal Investigator |
USUDA Jitsuo 東京医科大学, 医学部, 准教授 (60338803)
|
Co-Investigator(Kenkyū-buntansha) |
IKEDA Norihiko 東京医科大学, 外科学, 教授 (70246205)
一ノ瀬 修二 東京医科大学, 医学部, 助教 (10424491)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 光線力学治療 / 胸膜中皮腫 / 発光ダイオード / 悪性胸膜中皮腫 / LED / PDT / 光線力学的治療 |
Research Abstract |
It was able to gather rays of light from LED using lens and photodynamic therapy using LED plus lens killed malignant mesothelioma cells. Moreover, combination treatment, consisting of pemetrexed followed by NPe6-PDT, should be further investigated as a new treatment modality for malignant pleural mesothelioma. In the future, this combination treatment, PDT using LED plus lens and pemetrexed, may contribute to a reduction in local recurrence and a prolonged survival period in patients with malignant pleural mesothelioma.
|