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Design on Guide Wire Type Stirrer for Thrombus Dissolution, and Establish Intravascular Clot Crushing Method and Recanalization Treatment Method

Research Project

Project/Area Number 21591842
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionYamaguchi University

Principal Investigator

MORITA Minoru (2010-2011)  山口大学, 大学院・理工学研究科, 助教 (80510685)

加藤 祥一 (2009)  Yamaguchi University, 大学院・医学系研究科, 准教授 (00204470)

Co-Investigator(Kenkyū-buntansha) JIANG Zhongwei  山口大学, 大学院・理工学研究科, 教授 (60225357)
SUZUKI Michiyasu  山口大学, 大学院・医学系研究科, 教授 (80196873)
森田 実  山口大学, 大学院・理工学研究科, 助教 (80510685)
Co-Investigator(Renkei-kenkyūsha) SHIRAO Satoshi  山口大学, 医学部付属病院, 医員 (70448281)
Research Collaborator MOHAMMAD Ajoudanian  山口大学, 大学院・理工学研究科, 学生
SHIBASAKI Kenta  山口大学, 大学院・理工学研究科, 学生
KAZUNORI Yamamoto  山口大学, 大学院・理工学研究科, 学生
YUKI Nobuta  山口大学, 工学部・機械工学科, 学生
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords医療・福祉 / マイクロマシン / 微小共振器 / 設計工学 / 流体工学 / 振動子 / 血栓 / ガイドワイヤー / 破砕 / 再開通 / 吸引
Research Abstract

The therapeutic instrument to achieve the maximum effect in the tight space is necessary to dissolve the clot made in the intravascular effectively. This research proposed the new stirrer which transmits the longitudinal elastic wave through the catheter and converts to a bending motion at the tip stirrer is designed in order to get high performance of thrombus dissolution. It was confirmed that the stirrer had a big effect that the clot was able to be dissolved from the experiment.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (32 results)

All 2011 2010 2009

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (22 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Design of a Novel Type Micro-Stirrer Excited by Longitudinal Elastic Wave for Thrombus Dissolution2011

    • Author(s)
      A Mohammad, Z Jiang, M Morita
    • Journal Title

      J. Biomech. Sci. and Eng

      Volume: Vol.6No.4 Pages: 262-269

    • NAID

      130000965708

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Study on a new type micro-stirrer excited by longitudinal elastic wave for thrombus dissolution2011

    • Author(s)
      M Ajoudanian, Z Jiang, M Morita
    • Journal Title

      IJAEM

      Volume: 37 Pages: 67-77

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Design of a Novel Type Micro-Stirrer Excited by Longitudinal Elastic Wave for Thrombus Dissolution2011

    • Author(s)
      Ajoudanian Mohammad
    • Journal Title

      Journal of Biomechanical Science and Engineering

      Volume: 6 Issue: 4 Pages: 262-269

    • DOI

      10.1299/jbse.6.262

    • NAID

      130000965708

    • ISSN
      1880-9863
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study on a new type micro-stirrer excited by longitudinal elastic wave for thrombus dissolution2011

    • Author(s)
      Ajoudanian Mohammad
    • Journal Title

      International Journal of Applied Electromagnetics and Mechanics

      Volume: 37 Issue: 1 Pages: 67-77

    • DOI

      10.3233/jae-2011-1396

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Release Control of Drug-encapsulated Liposomes by Piezoelectric Ultrasonic Probe2010

    • Author(s)
      Z Jiang, G Chen, T Kawazu, M Morita
    • Journal Title

      IJAEM, ISO Press

      Volume: Volume34, Number1-2 Pages: 87-98

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Release Control of Drug-encapsulated Liposomes by Piezoelectric Ultrasonic Probe2010

    • Author(s)
      Zhongwei Jiang
    • Journal Title

      International Journal of Applied Electromagnetics and Mechanics

      Volume: Volume 34, Number 1-2 Pages: 87-98

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 血栓溶解用撹搾カテーテルの設計に関する研究2009

    • Author(s)
      森田実
    • Journal Title

      日本機械学会2009年度年次大会講演論文集 7巻

      Pages: 291-292

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design and Development of Micro Stirrer Used with Catheter for Dissolution Cerebral Thrombus2009

    • Author(s)
      Zhongwei Jiang
    • Journal Title

      Proceedings of the 2nd International Symposium on Digital Manufacturing(ISDM 2009)

      Pages: 22-26

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structure Design of Micro-Stirrer for Thrombus Dissolution2009

    • Author(s)
      Minoru Morita
    • Journal Title

      2009 International Conference on Mechatronics and Information Technology 7巻

      Pages: 329-330

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 血栓溶解用マイクロ攪拌システムの開発(撹拌動作解析と制御)2011

    • Author(s)
      内海聡
    • Organizer
      日本機械学会 中国四国支部 第49期総会・講演会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-03-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] 超音波照射によるリポソームの再構成及び薬剤封入特性の調査2011

    • Author(s)
      桑田明
    • Organizer
      日本機械学会 中国四国学生会 第41回学生員卒業研究発表講演会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-03-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血栓溶解用マイクロ攪拌装置の振動モード解析と制御2011

    • Author(s)
      林一茂
    • Organizer
      日本機械学会 中国四国学生会 第41回学生員卒業研究発表講演会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2011-03-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Development of Micro Cantilever Device for Dissolving Blood Clot~Experimental Validation of Wire Type Stirrer~2011

    • Author(s)
      K Shibasaki, M Morita, Z Jiang
    • Organizer
      Proc. of the 3rd ISDM2011
    • Place of Presentation
      RIHGA Royal Hotel Kokura, Kitakyushu
    • Related Report
      2011 Final Research Report
  • [Presentation] 血栓溶解用マイクロ攪拌器の動作解析と制御に関する研究2011

    • Author(s)
      森田実, 鈴木倫保, 江鐘偉
    • Organizer
      日本機械学会2011年度年次大会DVD-ROM論文集
    • Place of Presentation
      東京工業大学,東京
    • Related Report
      2011 Final Research Report
  • [Presentation] Development of Micro-Stirrer System for Thrombus Dissolution~Motion Analysis and Control~2011

    • Author(s)
      M Morita, S Utsumi, Z Jiang
    • Organizer
      Proc. of ICMIT 2011
    • Place of Presentation
      Shenyang, China
    • Related Report
      2011 Final Research Report
  • [Presentation] Study on Measuring Method of Thrombolyses for Wire Type Stirrer2011

    • Author(s)
      M Morita, M Ajoudanian, M Suzuki and Z Jiang
    • Organizer
      WOSSPA 2011
    • Place of Presentation
      Tipaza, Algeria
    • Related Report
      2011 Final Research Report
  • [Presentation] 血栓溶解用振動カテーテルの先端構造設計及び解析2011

    • Author(s)
      森田実, 江鐘偉, モハマドアジュダニアン, 鈴木倫保, 白尾敏之, 岡史朗
    • Organizer
      日本機械学会第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本大学,熊本
    • Related Report
      2011 Final Research Report
  • [Presentation] Development of Micro Cantilever Device for Dissolving Blood Clot~Experimental Validation of Wire Type Stirrer~2011

    • Author(s)
      Kenta Shibasaki
    • Organizer
      Proceedings of the 3rd International Symposium on Digital Manufacturing 2011
    • Place of Presentation
      RIGA Royal Hotel Kokura, Kitakyushu, Japan
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血栓溶解用マイクロ攪拌器の動作解析と制御に関する研究2011

    • Author(s)
      森田実
    • Organizer
      日本機械学会2011年度年次大会
    • Place of Presentation
      東京工業大学,東京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] Development of Micro-Stirrer System for Thrombus Dissolution~Motion Analysis and Control~2011

    • Author(s)
      Minoru Morita
    • Organizer
      International Conference on Mechatronics and Information Technology, Proceedings of ICMIT 2011
    • Place of Presentation
      Shenyang, China
    • Related Report
      2011 Annual Research Report
  • [Presentation] Study on Measuring Method of Throrabolyses for Wire Type Stirrer2011

    • Author(s)
      Minoru Morita
    • Organizer
      The 7th International Workshop on Systems, Signal Processing and their Applications
    • Place of Presentation
      Tipaza, Algeria
    • Related Report
      2011 Annual Research Report
  • [Presentation] 血栓溶解用振動カテーテルの先端構造設計及び解析2011

    • Author(s)
      森田実
    • Organizer
      日本機械学会 第23回バイオエンジニアリング講演会
    • Place of Presentation
      熊本大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] Study on micro piezoelectric actuator by using longitudinal wave energy for catheter application2010

    • Author(s)
      M Ajoudanian, Z Jiang, M Morita
    • Organizer
      ASME international mechanical engineering congress & exposition
    • Place of Presentation
      Vancouver, Canada
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] Analysis and modeling of vibratable end-effector of catheter for thrombus dissolution2010

    • Author(s)
      M Ajoudanian, Z Jiang, M Morita
    • Organizer
      ASME conference on smart materials, adaptive structures and intelligent systems, SMASIS2010-3712
    • Place of Presentation
      Philadelphia, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] 血栓溶解用曲げ振動カテーテルのエンドエフェクタ設計及び解析2010

    • Author(s)
      森田実, モハマドアジュダニアン, 江鐘偉
    • Organizer
      日本機械学会2010年度年次大会講演論文集
    • Place of Presentation
      名古屋工業大学,名古屋市
    • Related Report
      2011 Final Research Report
  • [Presentation] Analysis and modeling of vibratable end-effector of catheter for thrombus dissolution2010

    • Author(s)
      M.Ajoudanian
    • Organizer
      ASME conference on smart materials, adaptive structures and intelligent systems
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血栓溶解用曲げ振動カテーテルのエンドエフェクタ設計及び解析2010

    • Author(s)
      森田実
    • Organizer
      日本機械学会2010年度年次大会講演論文集
    • Place of Presentation
      名古屋工業大学
    • Related Report
      2010 Annual Research Report
  • [Presentation] 血栓溶解用撹拌カテーテルの設計に関する研究2009

    • Author(s)
      森田実
    • Organizer
      日本機械学会2009年度年次大会
    • Place of Presentation
      岩手
    • Year and Date
      2009-09-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] Structure Design of Micro-Stirrer for Thrombus Dissolution2009

    • Author(s)
      M Morita, Z Jiang, S Kato, M Suzuki
    • Organizer
      ICMIT2009
    • Place of Presentation
      Gwangju, Korea
    • Related Report
      2011 Final Research Report
  • [Presentation] Design and Development of Micro Stirrer Used with Catheter for Dissolution Cerebral Thrombus2009

    • Author(s)
      Zhongwei Jian
    • Organizer
      Proceedings of the 2nd International Symposium on Digital. Manufacturing(ISDM 2009)
    • Place of Presentation
      武漢(中国)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Structure Design of Micro-Stirrer for Thrombus Dissolution"2009

    • Author(s)
      Minoru Morita
    • Organizer
      2009 International Conference on Mechatronics and Info rmation Technology
    • Place of Presentation
      光州(韓国)
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 長尺部材の横振動生成方法及び振動部を備えるマイクロデバイス2010

    • Inventor(s)
      江鐘偉, 森田実, モハマドアジュダニアン
    • Industrial Property Rights Holder
      国立大学法人山口大学
    • Industrial Property Number
      2010-150714
    • Filing Date
      2010-07-01
    • Related Report
      2011 Final Research Report 2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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