| Project/Area Number |
21591849
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KURATSU Jun-ichi 熊本大学, 大学院・生命科学研究部, 教授 (20145296)
平井 俊範 熊本大学, 大学院・生命科学研究部, 准教授 (40274724)
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| Co-Investigator(Renkei-kenkyūsha) |
HIRAI Toshihiro 熊本大学, 大学院・生命科学研究部, 准教授 (40274724)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 視床痛 / Voxel-based morophometry / 痛み対応電流 / visual analog scale / 脳深部刺激術 / 内包後脚 / 視床通 |
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| Research Abstract |
Thalamic pain is the most intense among intractable pain syndromes. By using an apparatus producing pain-less electrical stimuli, we established a method of quantitative analysis of the degree of pain that does not rely on subjective criteria. After surgical intervention(deep brain stimulation for posterior limb of the internal capsule), pain degree(PD) is parallel to traditional subjective pain scale(visual analog scale ; VAS) in shortly(within 6 months), but they tended to dissociate later. VAS was modified to worse, whereas PD maintained to improve up to 36 months. Currently, we are accumulating image data for clarifying fine structural changes in brain underlying thalamic pain by using voxel-based morphometry(VBM).
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