• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The development of the new therapy by kinetic analysis and the redox adjustment of the oxidative stress in cerebrovascular disorder.

Research Project

Project/Area Number 21591856
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionIwate Medical University

Principal Investigator

YOSHIDA Kenji  岩手医科大学, 医学部, 講師 (10316367)

Co-Investigator(Renkei-kenkyūsha) OGASAWARA Kuniaki   (00305989)
KUBO Yoshitaka   (00316366)
KASHIMURA Hiroshi   (20398473)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords脳血管障害 / 酸化ストレス / 動脈硬化症 / 虚血再灌流 / 頸部頸動脈狭窄症 / 頸部頚動脈狭窄
Research Abstract

We analyzed the effect that cerebral ischaemia/reperfusion in ischemic cerebrovascular disease and the surgical treatment, made clear that hyperperfusion after the recanalization correlated with degree of cerebral ischaemia. The improvement of a postoperative cognitive function did that we correlated with improvement the benzodiazepine receptor function of the brain cortex nerve cells. Also, we reported the first time that these phenomenon were reversible changes. We established the new examination technique of the SPECT for cerebral metabolism that could evaluate without use the frequent medicine of the side effect.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (112 results)

All 2012 2011 2010 2009

All Journal Article (35 results) (of which Peer Reviewed: 35 results) Presentation (77 results)

  • [Journal Article] Comparison of early and late images on 123I-iomazenil SPECT with cerebral blood flow and oxygen extraction fraction images on PET in the cerebral cortex of patients with chronic unilateral major cerebral artery occlusive disease2012

    • Author(s)
      Suzuki T, Ogasawara K, Kuroda H, Chida K, Aso K, Kobayashi M, Fujiwara S, Yoshida K, Terasaki K, Ogawa A.
    • Journal Title

      Nucl Med Commun

      Volume: 33 Pages: 171-178

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Combination of preoperative cerebral blood flow and 123I-iomazenil SPECT imaging predicts postoperative cognitive improvement in patients undergoing uncomplicated endarterectomy for unilateral carotid stenosis2012

    • Author(s)
      Yamashita T, Ogasawara K, Kuroda H, Suzuki T, Chida K, Kobayashi M, Yoshida K, Kubo Y, Ogawa A.
    • Journal Title

      Clin Nucl Med

      Volume: 37 Pages: 128-133

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases : comparison with cerebrovascular reactivity to acetazolamide and cerebral blood flow SPECT imaging2012

    • Author(s)
      Kuroda H, Ogasawara K, Suzuki T, Chida K, Aso K, Kobayashi M, Yoshida K, Terasaki K, Fujiwara S, Kubo Y, Ogawa A.
    • Journal Title

      Clin Nucl Med

      Volume: 37 Pages: 135-240

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Improvement and impairment in cognitive function after carotid endarterectomy : comparison of objective and subjective assessments2012

    • Author(s)
      Yoshida K, Ogasawara K, Kobayashi M, Yoshida K, Kubo Y, Otawara Y, Ogawa A.
    • Journal Title

      Neurol Med Chir

      Volume: 52 Pages: 154-160

    • NAID

      10030127628

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ischemic events due to intraoperative microemboli developing in the cerebral hemisphere contralateral to carotid endarterectomy in a patient with preoperative cerebral hemodynamic impairment2012

    • Author(s)
      Kobayashi M, Ogasawara K, Suzuki T, Kuroda H, Yamashita T, Yoshida K, Kubo Y, Ogawa A.
    • Journal Title

      Neurol Med Chir(Tokyo)

      Volume: 52 Pages: 161-164

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ischemic Events Due to Intraoperative Microemboli Developing in the Cerebral Hemisphere Contralateral to Carotid Endarterectomy in a Patient With Preoperative Cerebral Hemodynamic Impairment2012

    • Author(s)
      Kobayashi M
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 52 Issue: 3 Pages: 161-164

    • DOI

      10.2176/nmc.52.161

    • NAID

      10030127661

    • ISSN
      0470-8105, 1349-8029
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement and Impairment in Cognitive Function After Carotid Endarterectomy: Comparison of Objective and Subjective Assessments2012

    • Author(s)
      Yoshida K
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 52 Issue: 3 Pages: 154-160

    • DOI

      10.2176/nmc.52.154

    • NAID

      10030127628

    • ISSN
      0470-8105, 1349-8029
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases : comparison with cerebrovascular reactivity to acetazolamide and cerebral blood flow SPECT imaging2012

    • Author(s)
      Kuroda H
    • Journal Title

      Clin Nucl Med

      Volume: 37 Issue: 3 Pages: 235-240

    • DOI

      10.1097/rlu.0b013e31823ea69f

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative central benzodiazepine receptor binding potential and cerebral blood flow images on SPECT predict development of new cerebral ischemic events and cerebral hyperperfusion after carotid endarterectomy2011

    • Author(s)
      Sato Y, Ogasawara K, Kuroda H, Suzuki T, Chida K, Fujiwara S, Aso K, Kobayashi M, Yoshida K, Terasaki K, Ogawa A.
    • Journal Title

      J Nucl Med

      Volume: 52 Pages: 1400-1407

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adverse effects of intravenous acetazolamide administration for evaluation of cerebrovascular reactivity using brain perfusion single-photon emission computed tomography in patients with major cerebral artery steno-occlusive diseases2011

    • Author(s)
      Saito H, Ogasawara K, Suzuki T, Kuroda H, Kobayashi M, Yoshida K, Kubo Y, Ogawa A.
    • Journal Title

      Neurol Med Chir

      Volume: 51 Pages: 479-483

    • NAID

      10029138411

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Postoperative resolution of 123I-iomazenil uptake and metabolic rate of oxygen in the cerebral cortex accompanied by postoperative improvement of cognition in a patient undergoing extracranial-intracranial arterial bypass surgery for internal carotid artery occlusion : a case report2011

    • Author(s)
      Chida K, Ogasawara K, Aso K, Kuroda H, Saito H, Kobayashi M, Yoshida K, Ogawa A.
    • Journal Title

      Clin Nucl Med

      Volume: 36 Pages: 361-362

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Central benzodiazepine receptor binding potential and CBF images on SPECT correlate with oxygen extraction fraction images on PET in the cerebral cortex with unilateral major cerebral artery occlusive disease2011

    • Author(s)
      Chida K, Ogasawara K, Kuroda H, Aso K, Kobayashi M, Fujiwara S, Yoshida K, Terasaki K, Ogawa A.
    • Journal Title

      J Nucl Med

      Volume: 52 Pages: 511-518

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intentional hypertension during dissection of carotid arteries in endarterectomy prevents postoperative development of new cerebral ischemic lesions caused by intraoperative microemboli2011

    • Author(s)
      Kobayashi M, Ogasawara K, Yoshida K, Sasaki M, Kuroda H, Suzuki T, Kubo Y, Fujiwara S, Ogawa A.
    • Journal Title

      Neurosurgery

      Volume: 69 Pages: 301-307

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Preoperative central benzodiazepine receptor binding potential and cerebral blood flow images on SPECT predict development of new cerebral is chemic events and cerebral hyperperfusion after carotid endarterectomy2011

    • Author(s)
      Sato Y
    • Journal Title

      J Nucl Med

      Volume: 52 Issue: 9 Pages: 1400-1407

    • DOI

      10.2967/jnumed.111.087940

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adverse Effects of Intravenous Acetazolamide Administration for Evaluation of Cerebrovascular Reactivity Using Brain Perfusion Single-Photon Emission Computed Tomography in Patients With Major Cerebral Artery Steno-occlusive Diseases2011

    • Author(s)
      Saito H
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 51 Issue: 7 Pages: 479-483

    • DOI

      10.2176/nmc.51.479

    • NAID

      10029138411

    • ISSN
      0470-8105, 1349-8029
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intentional hypertension during dissection of carotid arteries in endarte rectomy prevents postoperative development of new cerebral ischemic lesions caused by intraoperative microemboli2011

    • Author(s)
      Kobayashi M
    • Journal Title

      Neurosurgery

      Volume: 69 Issue: 2 Pages: 301-307

    • DOI

      10.1227/neu.0b013e318214abf6

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interesting image. I-123 iomazenil SPECT imaging in a patient with hemispheric brain damage due to cerebral ischemia during carotid endarterectomy2010

    • Author(s)
      Kobayashi M, Ogasawara K, Aso K, Chida K, Kuroda H, Yoshida K, Ogawa A.
    • Journal Title

      Clin Nucl Med

      Volume: 35(1) Pages: 51-52

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex : a SPECT study2010

    • Author(s)
      Chida K, Ogasawara K, Aso K, Suga Y, Kobayashi M, Yoshida K, Terasaki K, Tsushina E, Ogawa A.
    • Journal Title

      Cerebrovasc Dis

      Volume: 29 Pages: 343-351

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Scar formation in the carotid sheath identified during carotid endarterectomy in patients with previous cardiac surgery : significance of history of intraoperative Swan-Ganz catheter insertion.2010

    • Author(s)
      Yoshida K, Ogasawara K, Kobayashi M, Tsuboi J, Okabayashi H, Ogawa A.
    • Journal Title

      J Neurosurg

      Volume: 133 Pages: 885-889

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Arterial bypass surgery using a spontaneously formed "bonnet" superficial temporal artery in a patient with symptomatic common carotid artery occlusion : case report2010

    • Author(s)
      Aso K, Ogasawara K, Kobayashi M, Yoshida K.
    • Journal Title

      Neurosurgery

      Volume: 67

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain temperature measured by using proton MR spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy2010

    • Author(s)
      Murakami T, Ogasawara K, Yoshioka Y, Ishigaki D, Sasaki M, Kudo K, Aso K, Nishimoto H, Kobayashi M, Yoshida K, Ogawa A.
    • Journal Title

      Radiology

      Volume: 256 Pages: 924-931

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Easy dissection of the interhemispheric fissure for treatment of the anterior communicating artery aneurysm by the pterional approach2010

    • Author(s)
      Kashimura H, Kubo Y, Ogasawara K, Kakino S, Yoshida K, Ogawa A.
    • Journal Title

      World Neurosurg

      Volume: 73 Pages: 688-690

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Easy dissection of the interhemispheric fissure for treatment of the anterior communicating artery aneurysm by the pterional approach.2010

    • Author(s)
      Kashimura H
    • Journal Title

      World Neurosurg.

      Volume: 73 Pages: 688-690

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain temperature measured by using proton MR spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy.2010

    • Author(s)
      Murakami T
    • Journal Title

      Radiology.

      Volume: 256 Pages: 924-931

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Arterial bypass surgery using a spontaneously formed "bonnet" superficial temporal artery in a patient with symptomatic common carotid artery occlusion : case report.2010

    • Author(s)
      Aso K
    • Journal Title

      Neurosurgery.

      Volume: 67

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Scar formation in the carotid sheath identified during carotid endarterectomy in patients with previous cardiac surgery : significance of history of intraoperative Swan-Ganz catheter insertion. Clinical article.2010

    • Author(s)
      Yoshida K
    • Journal Title

      J Neurosurg.

      Volume: 133 Pages: 885-9

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex : a SPECT study.2010

    • Author(s)
      Chida K
    • Journal Title

      Cerebrovasc Dis.

      Volume: 29 Pages: 343-351

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interesting image. I-123 iomazenil SPECT imaging in a patient with hemispheric brain damage due to cerebral ischemia during carotid endarte rectomy.2010

    • Author(s)
      Kobayashi M
    • Journal Title

      Clin Nucl Med. 35(1)

      Pages: 51-52

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-ioma zenil uptake in the cerebral cortex : a SPECT study.2010

    • Author(s)
      Chida K
    • Journal Title

      Cerebrovasc Dis. 29(4)

      Pages: 343-351

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain temperature measured using proton MR spectroscopy detects cerebral hemodynamic impairment in patients with unilateral chronic major cerebral artery steno-occlusive disease : comparison with positron emission tomography2009

    • Author(s)
      Ishigaki D, Ogasawara K, Yoshioka Y, Chida K, Sasaki M, Fujiwara S, Aso K, Kobayashi M, Yoshida K, Terasaki K, Inoue T, Ogawa A.
    • Journal Title

      Stroke

      Volume: 40(9) Pages: 3012-3016

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Early post-ischemic hyperemia on transcranial cerebral oxygen saturation monitoring in carotid endarterectomy is associated with severity of cerebral ischemic insult during carotid artery clamping2009

    • Author(s)
      Kobayashi M, Ogasawara K, Suga Y, Chida K, Yoshida K, Otawara Y, Tsushima E, Ogawa A.
    • Journal Title

      Neurol Res

      Volume: 31(7) Pages: 728-33

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Application of fenestrated aneurysm clip for incomplete clamping of the common carotid artery during carotid endarterectomy : technical note2009

    • Author(s)
      Kobayashi M, Ogasawara K, Yoshida K, Otawara Y, Ogawa A.
    • Journal Title

      Neurol Med Chir(Tokyo)

      Volume: 49(5) Pages: 225-6

    • NAID

      10025947825

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Brain temperature measured using proton MR spectroscopy detects cerebral hemodynamic impairment in patients with unilateral chronic major cerebral artery steno-occlusive disease : comparison with positron emission tomography.2009

    • Author(s)
      Ishigaki D
    • Journal Title

      Stroke. 40(9)

      Pages: 3012-3016

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Application of fenestrated aneurysm clip for incomplete clamping of the common carotid artery during carotid endarterectomy : technical note.2009

    • Author(s)
      Kobayashi M
    • Journal Title

      Neurol Med Chir (Tokyo). 2009 May ; 49(5) : 225-6 ; 49(5)

      Pages: 225-226

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Early post-ischemic hyperemia on transcranial cerebral oxygen saturation monitoring in carotid endarterectomy is associated with severity of cerebral ischemic insult during carotid artery clamping.2009

    • Author(s)
      Kobayashi M
    • Journal Title

      Neurol Res. 2009 Sep ; 31(7) : 728-33. 31(7)

      Pages: 728-733

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 脳血管反応性測定のためのアセトゾラマイド投与による副作用の検討ton MRSを用いた非侵略的脳温測定による慢性脳虚血における脳循環代謝の評価: PETとの比較2011

    • Author(s)
      斎藤秀夫
    • Organizer
      第18回東北脳循環カンファランス
    • Place of Presentation
      仙台
    • Year and Date
      2011-11-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 脳血管反応性測定のためのアセトゾラマイド投与による副作用の検討ton MRSを用いた非侵略的脳温測定による慢性脳虚血における脳循環代謝の評価:PETとの比較2011

    • Author(s)
      斎藤秀夫
    • Organizer
      第18回東北脳循環カンファランス
    • Place of Presentation
      仙台
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術と脳循環代謝2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第19回21世紀脳循環代謝カンファレンス
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術と脳循環代謝2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第19回21世紀脳循環代謝カンファレンス
    • Place of Presentation
      大阪(招待演者)
    • Year and Date
      2011-11-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第四報:頚動脈内膜剥離術後の合併症の出現予知への応用2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第三報:トレーサ単回投与の後期/早期画像による可能性2011

    • Author(s)
      鈴木太郎
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第二報: SPECT-diamox反応性との精度比較2011

    • Author(s)
      黒田博紀
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Final Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第一報: PET-酸素摂取画像との比較による検証2011

    • Author(s)
      千田光平
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Final Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第二報:SPECT-diamox反応性との精度比較2011

    • Author(s)
      黒田博紀
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Iomazenil SPECTを用いた貧困灌流擬似画像:第一報:PET-酸素摂取画像との比較による検証2011

    • Author(s)
      千田光平
    • Organizer
      第23回日本脳循環代謝学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Post carotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex : a SPECT study2011

    • Author(s)
      Chida K.
    • Organizer
      The 5th Japanese-Korean Joint Stroke Conference
    • Place of Presentation
      韓国・慶州
    • Year and Date
      2011-10-28
    • Related Report
      2011 Final Research Report
  • [Presentation] Brain temperature measured by proton magnetic resonance spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy2011

    • Author(s)
      Murakami T.
    • Organizer
      The 5th Japanese-Korean Joint Stroke Conference
    • Place of Presentation
      韓国・慶州
    • Year and Date
      2011-10-28
    • Related Report
      2011 Final Research Report
  • [Presentation] Post carotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex : a SPECT study2011

    • Author(s)
      Chida K
    • Organizer
      The 5th Japanese-Korean Joint Stroke Conference
    • Place of Presentation
      韓国、慶州
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Brain temperature measured by proton magnetic resonance spectroscopy predicts cerebral hyperperfusion after carotid endarterectomy2011

    • Author(s)
      Murakami T
    • Organizer
      The 5th Japanese-Korean Joint Stroke Conference
    • Place of Presentation
      韓国、慶州
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚部頚動脈狭窄症における外科治療の脳合併症と発生メカニズム: Update2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第11回ブレインアタックカンファレンス
    • Place of Presentation
      福岡
    • Year and Date
      2011-10-21
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚部頚動脈狭窄症における外科治療の脳合併症と発生メカニズム:Update2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第11回ブレインアタックカンファレンス
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳主幹動脈瘤狭窄閉塞症例に対し脳血流SPECTで脳血管反応性を評価するために用いられるacetazolamide静脈内投与の副作用2011

    • Author(s)
      斎藤秀夫
    • Organizer
      (社)日本脳神経外科学会第70回学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-10-12
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術後過灌流は大脳白質損傷をきたし術後認知機能障害の原因となる: MRI拡散テンソルによる検討2011

    • Author(s)
      西本英明
    • Organizer
      (社)日本脳神経外科学会第70回学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-10-12
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術後過灌流は大脳白質損傷をきたし術後認知機能障害の原因となる:MRI拡散テンソルによる検討2011

    • Author(s)
      西本英明
    • Organizer
      (社)日本脳神経外科学会第70回学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2011-10-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Japanese CNS presidential lecture.2011

    • Author(s)
      Ogasawara K.
    • Organizer
      The 6st CNS Annual Meeting
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] Japanese CNS presidential lecture2011

    • Author(s)
      Ogasawara K
    • Organizer
      the 6st CNS Annual Meeting
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術における脳合併症の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      アテローム血栓症(ATIS)セミナー
    • Place of Presentation
      松本
    • Year and Date
      2011-09-02
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術における脳合併症の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      アテローム血栓症(ATIS)セミナー
    • Place of Presentation
      松本(招待講演)
    • Year and Date
      2011-09-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 慢性脳主幹動脈閉塞性疾患におけるiomazenil/脳血流SPECTによる脳酸素摂取鵜率画像2011

    • Author(s)
      千田光平
    • Organizer
      第30回The Mt. Fuji Workshop on CVD
    • Place of Presentation
      札幌
    • Year and Date
      2011-08-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 慢性脳主幹動脈閉塞性疾患におけるiomazenil/脳血流SPECTによる脳酸素摂取鵜率画像2011

    • Author(s)
      千田光平
    • Organizer
      第30回The Mt.Fuji Workshop on CVD
    • Place of Presentation
      札幌
    • Year and Date
      2011-08-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頸部頸動脈狭窄症に対する血行再建術前後の脳血流SPECTの有用性2011

    • Author(s)
      小笠原邦昭
    • Organizer
      STROKE 2011(第40回日本脳卒中の外科学会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術における頚動脈露出作業中の意図的昇圧は微小塞栓による脳虚巣出現を予防する2011

    • Author(s)
      小林正和
    • Organizer
      STROKE 2011(第40回日本脳卒中の外科学会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚部頚動脈血行再建術中のArtery-to-artery embolism-発生メカニズムと対策-2011

    • Author(s)
      小笠原邦昭
    • Organizer
      STROKE 2011(第40回日本脳卒中の外科学会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚部頚動脈狭窄症に対する血行再建術前後の脳血流SPECTの有用性2011

    • Author(s)
      小笠原邦昭
    • Organizer
      STROKE 2011(第40回日本脳卒中の外科学会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈内膜剥離術における頚動脈露出作業中の意図的昇圧は微小塞栓による脳虚巣出現を予防する2011

    • Author(s)
      小林正和
    • Organizer
      STROKE 2011(第36回日本脳卒中学会総会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚部頚動脈血行再建術中のArtery-to-artery embolism-発生メカニズムと対策2011

    • Author(s)
      小笠原邦昭
    • Organizer
      STROKE 2011(第40回日本脳卒中の外科学会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術における脳合併症の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      大分脳卒中学術講演会
    • Place of Presentation
      大分
    • Year and Date
      2011-07-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈狭窄症に対する血行再建術における脳合併症の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      大分脳卒中学術講演会
    • Place of Presentation
      大分(招待講演)
    • Year and Date
      2011-07-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈内膜剥離術における頚動脈露出作業中の意図的昇圧は微小塞栓による脳虚巣出現を予防する2011

    • Author(s)
      小林正和
    • Organizer
      第30回日本脳神経超音波学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2011-07-07
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 脳循環代謝検査の基礎と臨床応用2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第31回神経放射線ワークショップ
    • Place of Presentation
      八幡平市
    • Year and Date
      2011-07-01
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 頸動脈内膜剥離術-コツとピットフォールへの対処-2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第15回脳血管外科治療セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-30
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術-コツとピットフォールへの対処-2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第15回脳血管外科治療セミナー
    • Place of Presentation
      大阪(招待演者)
    • Year and Date
      2011-06-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚部頚動脈狭窄症における外科治療の脳合併症と発生メカニズム: Update2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第10回岡山脳卒中研究会
    • Place of Presentation
      岡山
    • Year and Date
      2011-06-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚部頚動脈狭窄症における外科治療の脳合併症と発生メカニズム:Update2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第10回岡山脳卒中研究会
    • Place of Presentation
      岡山(招待演者)
    • Year and Date
      2011-06-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頭部頸動脈血行再建術からみた脳血管障害の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第9回Vascular & Brain Conference-EAST
    • Place of Presentation
      東京
    • Year and Date
      2011-06-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 頭部頚動脈血行再建術からみた脳血管障害の発生メカニズム2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第9回Vascular&Brain Conference-EAST
    • Place of Presentation
      東京(招待演者)
    • Year and Date
      2011-06-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後の認知機能改善には脳血流及び脳代謝の改善が関与する2011

    • Author(s)
      麻生謙太
    • Organizer
      第10回日本頸部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 頸動脈内膜剥離術後過灌流は大脳白質損傷をきたし術後認知機能障害の原因となる: MRI拡散テンソルによる検討2011

    • Author(s)
      西本英明
    • Organizer
      第10回日本頸部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 頸動脈内膜剥離術における頚動脈露出操作中の意図的昇圧は微小塞栓による脳虚巣出現を予防する2011

    • Author(s)
      小林正和
    • Organizer
      第10回日本頸部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Final Research Report
  • [Presentation] CEAの脳合併症予防のための術中・術後管理2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第10回日本頸部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術後の認知機能改善には脳血流及び脳代謝の改善が関与する2011

    • Author(s)
      麻生謙太
    • Organizer
      第10回日本頚部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈内膜剥離術後過灌流は大脳白質損傷をきたし術後認知機能障害の原因となる:MRI拡散テンソルによる検討2011

    • Author(s)
      西本英明
    • Organizer
      第10回日本頚部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 頚動脈内膜剥離術における頚動脈露出操作中の意図的昇圧は微小塞栓による脳虚巣出現を予防する2011

    • Author(s)
      小林正和
    • Organizer
      第10回日本頚部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] CEAの脳合併症予防のための術中・術後管理2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第10回日本頚部脳血管治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] MRI及びSPECTを用いた新たな脳循環代謝画像2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第31回置賜地区画像診断研究会
    • Place of Presentation
      米澤
    • Year and Date
      2011-06-03
    • Related Report
      2011 Final Research Report
  • [Presentation] MRI及びSPECTを用いた新たな脳循環代謝画像2011

    • Author(s)
      小笠原邦昭
    • Organizer
      第31回置賜地区画像診断研究会
    • Place of Presentation
      米澤(招待演者)
    • Year and Date
      2011-06-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 心臓手術既往症例に対する頚動脈内膜剥離術: Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスク提唱2010

    • Author(s)
      吉田研二
    • Organizer
      第33回東北脳血管障害研究会
    • Place of Presentation
      仙台
    • Year and Date
      2010-12-04
    • Related Report
      2011 Final Research Report
  • [Presentation] 心臓手術既往症例に対する頚動脈内膜剥離術:Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスク提唱2010

    • Author(s)
      吉田研二
    • Organizer
      第33回東北脳血管障害研究会
    • Place of Presentation
      仙台
    • Year and Date
      2010-12-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 頚動脈内膜剥離術後脳虚血巣・虚血症状の出現を予知できる2010

    • Author(s)
      西本英明
    • Organizer
      (社)日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-29
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 心臓手術既往症例に対する頸動脈内膜剥離術: Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスクの提唱2010

    • Author(s)
      吉田研二
    • Organizer
      (社)日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 心臓手術既往症例に対する頸動脈内膜剥離術:Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスクの提唱2010

    • Author(s)
      吉田研二
    • Organizer
      (社)日本脳神経外科学会第69回学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 術前single-slab 3D-TOFは頚動脈内膜剥離術後脳虚血巣・虚血症状の出現を予知できる2010

    • Author(s)
      西本英明
    • Organizer
      第17回東北脳循環カンファランス
    • Place of Presentation
      仙台
    • Year and Date
      2010-10-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 摘出後人工血管置換による血行再建を行った頸部頸動脈分岐部血栓化動脈瘤の1例2010

    • Author(s)
      佐藤雄一
    • Organizer
      第46回(社)日本脳神経外科学会東北支部会
    • Place of Presentation
      山形
    • Year and Date
      2010-09-04
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 3本の分岐に血行再建を行った後trappingして根治せしめた血栓化巨大中大脳動脈瘤の1例2010

    • Author(s)
      幸治孝裕
    • Organizer
      第46回(社)日本脳神経外科学会東北支部会
    • Place of Presentation
      山形
    • Year and Date
      2010-09-04
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 123I-Iomazenilおよび123I-IMP SPECTによるmisery perfusionの検出;ダイアモックス反応性との比較2010

    • Author(s)
      黒田博紀
    • Organizer
      第20回東北脳SPECT研究会
    • Place of Presentation
      山形
    • Year and Date
      2010-09-03
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 脳幹部腹側へのアプローチにおけるDentate ligamaent牽引の有用性2010

    • Author(s)
      樫村博史
    • Organizer
      第29回The Mt. Fuji Workshop on CVD
    • Place of Presentation
      福岡
    • Year and Date
      2010-08-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 脳幹部腹側へのアプローチにおけるDentate ligamaent牽引の有用性2010

    • Author(s)
      樫村博史
    • Organizer
      第29回The Mt.Fuji Workshop on CVD
    • Place of Presentation
      福岡
    • Year and Date
      2010-08-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] proton MRSを用いた非侵襲的脳温測定による慢性脳虚血における脳循環代謝の評価: PETとの比較2010

    • Author(s)
      石垣大哉
    • Organizer
      第16回NMCC共同利用研究成果発表会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-05-14
    • Related Report
      2011 Final Research Report
  • [Presentation] proton MRSを用いた非侵襲的脳温測定による慢性脳虚血における脳循環代謝の評価:PETとの比較2010

    • Author(s)
      石垣大哉
    • Organizer
      第16回NMCC共同利用研究成果発表会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-05-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 開心術既往症例に対する頸動脈内膜剥離術: Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスクの提唱2010

    • Author(s)
      吉田研二
    • Organizer
      第9回日本頸部脳血管治療学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 開心術既往症例に対する頸動脈内膜剥離術:Swan-Ganzカテーテル挿入側認識の重要性と新たなCEAハイリスクの提唱2010

    • Author(s)
      吉田研二
    • Organizer
      第9回日本頸部脳血管治療学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後の認知機能改善は123I-iomazenil結合能に比例する2010

    • Author(s)
      千田光平
    • Organizer
      第9回日本頸部脳血管治療学会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-23
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後の認知機能改善は123I-iomazenil結合能に比例する2010

    • Author(s)
      千田光平
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-15
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] proton MRSを用いた非侵襲的脳温測定による慢性脳虚血における脳循環代謝の評価: PETとの比較2009

    • Author(s)
      小笠原邦昭
    • Organizer
      第16回東北脳循環カンファランス
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Related Report
      2011 Final Research Report
  • [Presentation] proton MRSを用いた非侵襲的脳温測定による慢性脳虚血における脳循環代謝の評価:PETとの比較2009

    • Author(s)
      小笠原邦昭
    • Organizer
      第16回東北脳循環カンファランス
    • Place of Presentation
      仙台
    • Year and Date
      2009-11-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後過灌流による大脳皮質神経細胞腫障害と高次脳機能障害: IMZ-SPECTによる検討2009

    • Author(s)
      千田光平
    • Organizer
      (社)日本脳神経外科学会第68回学術総会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 脳血流SPECTを用いたEC-IC bypass後の脳循環動態評価と臨床像:もやもや病と非もやもや病における比較検討2009

    • Author(s)
      千田光平
    • Organizer
      第19回東北脳SPECT研究会
    • Place of Presentation
      福島
    • Year and Date
      2009-09-11
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後過還流による大脳皮質神経細胞障害と高次脳機能障害: IMZ-SPECTによる検討2009

    • Author(s)
      千田光平
    • Organizer
      第15回NMCC共同利用研究成果発表会
    • Place of Presentation
      盛岡
    • Year and Date
      2009-05-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 頚動脈内膜剥離術中の不完全頚動脈遮断に対する有窓動脈瘤クリップの応用2009

    • Author(s)
      吉田研二
    • Organizer
      第18回脳神経外科手術と機器学会(CNTT)
    • Place of Presentation
      秋田
    • Year and Date
      2009-04-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 頸動脈内膜剥離術後過灌流による大脳皮質神経細胞腫障害と高次脳機能障害:IMZ-SPECTによる検討2009

    • Author(s)
      千田光平
    • Organizer
      (社)日本脳神経外科学会第68回学術総会
    • Place of Presentation
      東京
    • Related Report
      2009 Annual Research Report
  • [Presentation] 頸動脈内膜剥離術後過還流による大脳皮質神経細胞障害と高次脳機能障害:IMZ-SPECTによる検討2009

    • Author(s)
      千田光平
    • Organizer
      第15回NMCC共同利用研究成果発表会
    • Place of Presentation
      盛岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] 額動脈内膜剥離術中の不完全頚動脈遮断に対する有窓動脈瘤クリップの応用2009

    • Author(s)
      吉田研二
    • Organizer
      第18回脳神経外科手術と機器学会(CNTT)
    • Place of Presentation
      秋田
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi