Electrical Physiology and pharmacology of pregnancy-induced analgesia

• Project/Area Number: 21591994
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: Asahikawa Medical College
• Principal Investigator: IWASAKI Hiroshi 旭川医科大学, 医学部, 教授 (70223386)
• Co-Investigator(Kenkyū-buntansha): FUJITA Satoshi 旭川医科大学, 医学部, 教授 (10173428) ; MAMIYA Keiko 旭川医科大学, 医学部, 准教授 (80231603)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 内因性鎮痛 / GABA受容体 / NMDA受容体

Research Abstract

Neuropathic pain is often resistance to opioids. It is demonstrated that NMDA receptor anatagonist, ketamin ointment is a useful cancer pain treatment(ASA2010A308). Cervical sympathetic ganglion may produce to increase neuropathic pain clinically. It is shown that transcutaneous Xe light irradiation around stellate ganglion significantly increase the drum temperature immediately(ASA2011, A470). These findings may contribute to treat neuropathic pain in a clinical practice.

Research Products

• [Presentation] Changes in the drum temperature after transcutaneous Xenon light irradiation around the stellate ganaglion (2011)
  • Author(s): Onodera Y, Mamiya K, Ueno M, Honma Y, Tanaka H, Sugawara A, Kanaki K, Iwasaki H
  • Organizer: Annual meeting of American Society of anesthesiologists
  • Place of Presentation: Chicago, USA
  • Year and Date: 2011-10-16
• [Presentation] Ketamin ointment for cancer patient (2011)
  • Author(s): Mamiya K, Harada S, Abe Y, Sasada T, Iwasaki H
  • Organizer: Annual meeting of American Society of Anesthesisologists
  • Place of Presentation: San Diego、USA
  • Year and Date: 2011-10-16
• [Presentation] Stress-Relieving Effect of Stellate Ganglion Block (2009)
  • Author(s): Keiko Mamiya, Yuko Homma, Osamu Takahata, Hiroshi Iwasaki
  • Organizer: Annual Meeting of American Society of Anesthesiologists
  • Place of Presentation: New Orleans, USA
• [Presentation] Pain Visionを用いた妊婦と非妊婦の知覚閾値の測定 (2009)
  • Author(s): 太田みさき, 間宮敬子, 上野恵, 高畑治, 岩崎寛
  • Organizer: 日本麻酔科学会第56回学術集会
  • Place of Presentation: 神戸
• [Presentation] Keatmin oiontment for cancer pain
  • Author(s): Mamiya K, Harada S, Abe Y, Sasada T, Iwasaki H.
  • Organizer: 2010 annual meeting of American Society of Anesthesiologists A308
• [Presentation] Changes in the drum temperature after transcutaneous Xenon light irradiation around the stellate ganglion
  • Author(s): Onodera Y, Mamiya K, Ueno M, Honma Y, Tanaka H, Sugawara A, Kanaki K, Iwasaki H.
  • Organizer: 2011 annual meeting of American Society of Anesthesiologists A470