Establishment of the novel targeted therapy and its biomarker for the patients with renal cell cancer

• Project/Area Number: 21592030
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Urology
• Research Institution: 公益財団法人がん研究会 (2011); Japanese Foundation For Cancer Research (2009-2010)
• Principal Investigator: YUASA Takeshi 公益財団法人がん研究会, がん化学療法センター臨床部, 研究員 (00314162)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 融合遺伝子 / 腎癌 / バイオマーカー / 一遺伝子多型 / 骨転移 / 分子標的治療 / 腎がん / 予後予測因子 / 血管新生阻害 / 前立腺癌 / 肺転移 / 覧癌

Research Abstract

We analyzed the treatment efficacy and safety profile of sunitinib for patients with metastatic renal cell cancer(RCC) in ordinary clinical practice. In addition, we investigated the prognostic clinicopathological factors in these patients. Sunitinib has a favorable efficacy/safety profile for Japanese metastatic RCC patients in clinical practice. MSKCC prognostic factors seem to be still valid to predict survival in metastatic RCC in the era of molecular targeted therapy.
In addition, we investigated the inhibitory effect of sunitinib against the progression of RCC in vitro and in vivo. Sunitinib did not inhibit the growth of RCC cells in vitro at clinically or experimentally achievable serum levels(100 nM. 1μM). However, sunitinib prevented the growth of ACHN^<Luc> RCC cells in the bone metastatic mouse model. The number of osteoclasts in sunitinib-treated mice was significantly less than that in control mice. Serum and urine levels of NTx in patients with metastatic RCC declined significantly during the first 4 weeks of sunitinib treatment.

Research Products

• [Journal Article] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function (2012)
  • Author(s): Maita S, Yuasa T, Tsuchiya N, Mitobe M, Narita S, Horikawa Y, Hatake K, Fukui I, Kimura S, Maekawa T, Habuchi T
  • Journal Title: Int J Cancer Volume: 130 Pages: 677-84
• [Journal Article] 進行性腎癌に対する分子標的治療薬・薬剤選択ガイド (2012)
  • Author(s): 湯浅健,高橋俊二
  • Journal Title: 分子標的治療の副作用マネージメントの要点は臨床泌尿器科 Volume: 66巻1号 Pages: 77-82
• [Journal Article] Molecular targeted therapies for patients with metastatic renal cell cancer (2012)
  • Author(s): Yuasa T, et al
  • Journal Title: Translational Med Volume: (In press)(未定)
  • Peer Reviewed
• [Journal Article] Prognostic Factors for Overall Survival in Japanese Patients with Metastatic Renal Cell Cancer Treated with Sunitinib (2012)
  • Author(s): Yuasa T, et al
  • Journal Title: BJU int. Volume: 130 Issue: 9 Pages: 677-84
  • DOI: 10.1111/j.1464-410x.2011.10534.x
  • Peer Reviewed
• [Journal Article] rognostic Impact of C-reactive Protein for Determining Overall Survival of Patients With Castration-resistant Prostate Cancer Treated With Docetaxel (2012)
  • Author(s): Ito M, et al.
  • Journal Title: Urology Volume: 130 Pages: 677-84
  • Peer Reviewed
• [Journal Article] Identification of ALK fusions in renal cancer : Large-scale immunohistochemical screening by intercalated antibody-enhanced polymer method (2012)
  • Author(s): Sugawara S, et al.
  • Journal Title: BJU int. Volume: (In press)(未定) Issue: 18 Pages: 4427-4436
  • DOI: 10.1002/cncr.27391
  • Peer Reviewed
• [Journal Article] Outcome, clinical prognostic factors and genetic predictors of adverse reactions of intermittent combination chemotherapy with docetaxel, estramustine phosphate and carboplatin for castration-resistant prostate cancer (2012)
  • Author(s): Narita S, Tsuchiya N, Yuasa T, et al.
  • Journal Title: BJU int. Volume: (In press)(未定)
  • NAID: 10030951423
  • Peer Reviewed
• [Journal Article] 【進行性腎癌に対する分子標的治療薬・薬剤選択ガイド】分子標的治療の副作用マネージメントの要点は? (2012)
  • Author(s): 湯浅健, 高橋俊二
  • Journal Title: 臨床泌尿器科 Volume: 66 Pages: 77-82
• [Journal Article] Treatment Outcome and Prognostic Factors of the Patients with Renal Cell Cancer Bone Metastasis (2011)
  • Author(s): Yuasa T, Urakami S, Yamamoto S, Yonese J, Takahashi S, Hatake K, Fukui I
  • Journal Title: Clin Exp Metastasis Volume: 28 Pages: 405-11
• [Journal Article] Tumor Size is a Potential Predictor of the Response to Tyrosine Kinase Inhibitors in Renal Cell Cancer (2011)
  • Author(s): Yuasa T, Urakami S, Yamamoto S, Yonese J, Nakano K, Kodaira M, Takahashi S, Hatake K, Inamura K, Ishikawa Y, Fukui I
  • Journal Title: Urology Volume: 77 Pages: 831-5
• [Journal Article] Outcome of Antegrade Radical Prostatectomy with Intended Wide Resection in Prostate Cancer Patients with a Preoperative Serum PSA Level> 100 ng/ml (2011)
  • Author(s): Urakami S, Yonese J, Yamamoto S, Yuasa T, Kitsukawa S, Numao N, Kubo Y, Ito M, Sukegawa G, Yasuda Y, Ishikawa Y, Fukui I
  • Journal Title: Urol Int Volume: 87 Pages: 175-81
• [Journal Article] Prognostic Impact of C-reactive Protein for Determining Overall Survival of Patients With Castration-resistant Prostate Cancer Treated With Docetaxel (2011)
  • Author(s): Ito M, Saito K, Yasuda Y, Sukegawa G, Kubo Y, Numao N, Kitsukawa S, Urakami S, Yuasa T, Yamamoto S, Yonese J, Fukui I
  • Journal Title: Urology Volume: 78 Pages: 1131-5
• [Journal Article] Outcome, clinical prognostic factors and genetic predictors of adverse reactions of intermittent combination chemotherapy with docetaxel, estramustine phosphate and carboplatin for castration-resistant prostate cancer (2011)
  • Author(s): Narita S, Tsuchiya N, Yuasa T, Maita S, Obara T, Numakura K, Tsuruta H, Saito M, Inoue T, Horikawa Y, Satoh S, Habuchi T
  • Journal Title: Int J Clin Oncol Volume: (in press)
  • NAID: 10030951423
• [Journal Article] What Is the Most Preferred Wound Site for Laparoscopic Donor Nephrectomy?: A Questionnaire Assessment (2011)
  • Author(s): Saito M, Tsuchiya N, Maita S, Numakura K, Obara T, Tsuruta H, Kumazawa T, Inoue T, Narita S, Horikawa Y, Yuasa T, Satoh S, Habuchi T
  • Journal Title: J Laparoendosc Adv Surg Tech A Volume: 21 Pages: 511-5
• [Journal Article] クイックマスター泌尿器科の病気・治療・ケア (2011)
  • Author(s): 湯浅健
  • Journal Title: 抗がん化学療法泌尿器ケア Volume: 16 Pages: 376-377
• [Journal Article] 前立腺がんの骨転移に対する治療update前立腺癌骨転移の薬物治療腫瘍内科の立場から (2011)
  • Author(s): 高橋俊二,湯浅健,福井巌
  • Journal Title: 泌尿器外科 Volume: 24巻8号 Pages: 1275-1277
• [Journal Article] 【がん化学療法の進歩】各論臓器別がん治療腎がん・尿路がん・膀胱がん (2011)
  • Author(s): 湯浅健,羽渕友則
  • Journal Title: 化学療法の領域 Volume: 27巻 Pages: 1180-1188
• [Journal Article] A case study of metastatic Xp11.2 translocation renal cell carcinoma effectively treated with sunitinib (2011)
  • Author(s): Numakura K, Tsuchiya N, Yuasa T, Saito M, Obara T, Tsuruta H, Narita S, Horikawa Y, Satoh S, Habuchi T
  • Journal Title: Int J Clin Oncol Volume: 16 Pages: 577-80
  • NAID: 10030246990
• [Journal Article] Biomarkers to Predict Response to Sunitinib Therapy and Prognosis in Metastatic Renal Cell Cancer (2011)
  • Author(s): Yuasa T, et al
  • Journal Title: Cancer Science Volume: 102 Issue: 11 Pages: 1949-57
  • DOI: 10.1111/j.1349-7006.2011.02054.x
  • NAID: 10030244632
  • Peer Reviewed
• [Journal Article] Outcome of Antegrade Radical Prostatectomy with Intended Wide Resection in Prostate Cancer Patients with a Preoperative Serum PSA Level >100ng/ml (2011)
  • Author(s): Urakami S, Yonese J, Yamamoto S, Yuasa T, et al
  • Journal Title: Urol Int Volume: 87 Pages: 175-81
  • Peer Reviewed
• [Journal Article] 前立腺がんの骨転移に対する治療update前立腺癌骨転移の薬物治療 (2011)
  • Author(s): 高橋俊二, 湯浅健, 福井巌
  • Journal Title: 泌尿器外科 Volume: 24 Pages: 1275-77
• [Journal Article] 【がん化学療法の進歩】各論臓器別がん治療腎がん・尿路がん・膀胱がん (2011)
  • Author(s): 湯浅健, 羽渕友則
  • Journal Title: 化学療法の領域 Volume: 27 Pages: 1180-88
• [Journal Article] 腎細胞癌の分子標的治療】mTOR阻害剤:everolimus (2011)
  • Author(s): 湯浅健
  • Journal Title: 医学のあゆみ Volume: 236 Pages: 107-110
• [Journal Article] 【クイックマスター泌尿器科の病気・治療・ケア】抗がん化学療法 (2011)
  • Author(s): 湯浅健
  • Journal Title: 泌尿器ケア Volume: 24 Pages: 1275-77
• [Journal Article] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function. (2011)
  • Author(s): Maita S, Yuasa T, et al.
  • Journal Title: International Journal of Cancer Volume: in press
  • Peer Reviewed
• [Journal Article] Treatment Outcome and Prognostic Factors of the Patients with Renal Cell Cancer Bone Metastasis. (2011)
  • Author(s): Yuasa T, et al.
  • Journal Title: Clinical Experimental Metastasis Volume: 28 Pages: 405-411
  • Peer Reviewed
• [Journal Article] Tumor Size is a Potential Predictor of the Response to Tyrosine Kinase Inhibitors in Renal Cell Cancer. (2011)
  • Author(s): Yuasa T, et al.
  • Journal Title: Urology Volume: 77 Pages: 831-835
  • Peer Reviewed
• [Journal Article] Overall Survival and Updated Results from a Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma. (2011)
  • Author(s): Tomita Y, Shinohara N, Yuasa T, et al.
  • Journal Title: Japanese Journal of Clinical Oncology Volume: 40 Pages: 1166-1172
  • Peer Reviewed
• [Journal Article] Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients. (2011)
  • Author(s): Yuasa T, et al.
  • Journal Title: Urology Volume: 75 Pages: 1131-1137
  • Peer Reviewed
• [Journal Article] Clinical Significance of Polymorphism and Expression of Chromogranin A and Endothelin-1 in Prostate Cancer. (2011)
  • Author(s): Ma Z, Tsuchiya N, Yuasa T, et al.
  • Journal Title: Journal of Urology Volume: 184 Pages: 1182-1188
  • Peer Reviewed
• [Journal Article] A case study of metastatic Xp 11.2 translocation renal cell carcinoma effectively treated with sunitinib. (2011)
  • Author(s): Numakura K, Tsuchiya N, Yuasa T, et al.
  • Journal Title: Japanese Journal of Clinical Oncology Volume: in press
  • NAID: 10030246990
  • Peer Reviewed
• [Journal Article] 【腎細胞癌の分子標的治療】mTOR阻害剤:everolimus (2011)
  • Author(s): 湯浅健
  • Journal Title: 医学のあゆみ Volume: 12 Pages: 1107-1110
• [Journal Article] Overall Survival and Updated Results from a Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma (2010)
  • Author(s): Tomita Y, Shinohara N, Yuasa T, Fujimoto H, Niwakawa M, Mugiya S, Miki T, Uemura H, Nonomura N, Takahashi M, Hasegawa Y, Agata N, Houk B, Naito S, Akaza H
  • Journal Title: Jpn J Clin Oncol Volume: 40 Pages: 1166-72
• [Journal Article] Erythema multiforme induced by sorafenib for metastatic renal cell carcinoma in Japanese patients (2010)
  • Author(s): Kodaira M, Takahashi S, Takeuchi K, Yuasa T, Saotome T, Yonese J, Fukui I, Hatake K
  • Journal Title: Ann Oncol Volume: 21 Pages: 1563-5
• [Journal Article] Clinical Significance of Polymorphism and Expression of Chromogranin A and Endothelin-1 in Prostate Cancer (2010)
  • Author(s): Ma Z, Tsuchiya N, Yuasa T, Huang M, Obara T, Narita S, Horikawa Y, Tsuruta H, Saito M, Satoh S, Ogawa O, Habuchi T
  • Journal Title: J Urol Volume: 184 Pages: 1182-8
• [Journal Article] Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients (2010)
  • Author(s): Yuasa T, Maita S, Tsuchiya N, Ma Z, Narita S, Horikawa Y, Yamamoto S, Yonese J, Fukui I, Takahashi S, Hatake K, Habuchi T
  • Journal Title: Urology Volume: 75 Pages: 1131-7
• [Journal Article] A Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma : Insights into the Treatment, Efficacy and Safety (2010)
  • Author(s): Uemura H, Shinohara N, Yuasa T, Tomita Y, Fujimoto H, Niwakawa M, Mugiya S, Miki T, Nonomura N, Takahashi M, Hasegawa Y, Agata N, Houk B, Naito S, Akaza H
  • Journal Title: Jpn J Clin Oncol Volume: 40 Pages: 194-202
• [Journal Article] 泌尿器科のがん化学療法Iレジメン・プロトコール入門 (2010)
  • Author(s): 湯浅健
  • Journal Title: 精巣腫瘍に対するがん化学療法のレジメン泌尿器ケア Volume: 15 Pages: 1006-1010
• [Journal Article] 腎細胞がんの治療をめぐって (2010)
  • Author(s): 湯浅健
  • Journal Title: 転移巣に対する治療をどう行うか骨転移巣に対する治療臨床腫瘍プラクティス Volume: 6 Pages: 67-73
• [Journal Article] 癌治療の現状と展望分子標的薬剤とバイオマーカー、有害事象管理 (2010)
  • Author(s): 湯浅健
  • Journal Title: 治療薬解説エベロリムスカレントテラピー Volume: 27 Pages: 1150-1155
• [Journal Article] 分子標的治療薬 (2010)
  • Author(s): 湯浅健,伊藤良則
  • Journal Title: Pazopanib Biotherapy Volume: 24 Pages: 516-519
• [Journal Article] 腎細胞癌の分子標的治療 (2010)
  • Author(s): 湯浅健
  • Journal Title: mTOR阻害剤: everolimus医学のあゆみ Volume: 236 Pages: 107-10
• [Journal Article] A Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma : Insights into the Treatment, Efficacy and Safe. (2010)
  • Author(s): Uemura H, Shinohara N, Yuasa T, et al.
  • Journal Title: Japanese Journal of Clinical Oncology Volume: 40 Pages: 194-202
  • Peer Reviewed
• [Journal Article] Erythema multiforme induced by sorafenib for metastatic renal cell carcinoma in Japanese patients. (2010)
  • Author(s): Kodaira M, Takahashi S, Takeuchi K, Yuasa T, et al.
  • Journal Title: Annals of Oncology Volume: 21 Pages: 1563-1565
  • Peer Reviewed
• [Journal Article] 分子標的治療薬 Pazopanib (2010)
  • Author(s): 湯浅健、伊藤良則
  • Journal Title: Biotherapy Volume: 24 Pages: 516-519
• [Journal Article] 【泌尿器科のがん化学療法Iレジメン・プロトコール入門】精巣腫瘍に対するがん化学療法のレジメン (2010)
  • Author(s): 湯浅健
  • Journal Title: 泌尿器ケア Volume: 15 Pages: 1006-1010
• [Journal Article] 【腎細胞がんの治療をめぐって】転移巣に対する治療をどう行うか 骨転移巣に対する治療 (2010)
  • Author(s): 湯浅健
  • Journal Title: 臨床腫瘍プラクティス Volume: 6 Pages: 67-73
• [Journal Article] A Phase II Study of Sunitinib in Japanese Patients with Metastatic Renal Cell Carcinoma : Insights into the Treatment, Efficacy and Safety (2010)
  • Author(s): Uemura H, Shinohara N, Yuasa T, et al.
  • Journal Title: Jpn J Clin Oncol. (in press)
  • Peer Reviewed
• [Journal Article] Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients (2010)
  • Author(s): 湯浅健, et al.
  • Journal Title: Urology (in press)
  • Peer Reviewed
• [Journal Article] 骨転移巣に対する治療 (2010)
  • Author(s): 湯浅健
  • Journal Title: 臨床腫瘍プラクティス 6 Pages: 67-73
• [Journal Article] 進行性腎細胞癌 治療の現状と将来(4);今できること! 治療戦略と工夫/ (2010)
  • Author(s): 大家基嗣, 釜井隆男, 中村英二郎, 湯浅健, 高橋正幸
  • Journal Title: Pharma Medica 27 Pages: 76-85
• [Journal Article] The novel tumor-suppressor Mel-18 in prostate cancer : its functional polymorphism, expression, and clinical significance (2009)
  • Author(s): Wang W, Yuasa T, Tsuchiya N, Ma Z, Maita S, Narita S, Kumazawa T, Inoue T, Tsuruta H, Horikawa Y, Saito M, Hu W, Ogawa O, Habuchi T
  • Journal Title: Int J Cancer Volume: 125 Pages: 2836-43
• [Journal Article] Intravesical administration of gammadelta T cells successfully prevents the growth of bladder cancer in the murine model (2009)
  • Author(s): Yuasa T, Sato K, Ashihara E, Takeuchi M, Maita S, Tsuchiya N, Habuchi T, Maekawa T, Kimura S
  • Journal Title: Cancer Immunol Immunother Volume: 58 Pages: 493-502
• [Journal Article] Editorial Comment to docetaxel-based combination chemotherapy with zoledronic acid and prednisone in hormone refractory prostate cancer : Factors predicting response and survival (2009)
  • Author(s): Yuasa T
  • Journal Title: Int J Urol Volume: 16 Pages: 731-2
  • NAID: 10025617806
• [Journal Article] Clinical significance of a single nucleotide polymorphism and allelic imbalance of matrix metalloproteinase-1 promoter region in prostate cancer (2009)
  • Author(s): Tsuchiya N, Narita S, Kumazawa T, Inoue T, Ma Z, Tsuruta H, Saito M, Horikawa Y, Yuasa T, Satoh S, Ogawa O, Habuchi T
  • Journal Title: Oncol Rep Volume: 22 Pages: 493-9
• [Journal Article] Cystoprostatectomy as a treatment of prostate cancer involving the bladder neck (2009)
  • Author(s): Kumazawa T, Tsuchiya N, Saito M, Inoue T, Narita S, Horikawa Y, Yuasa T, Satoh S, Kato T, Nanjyo H, Habuchi T
  • Journal Title: Urol Int Volume: 83 Pages: 141-5
• [Journal Article] MVAC療法後の転移性尿路上皮癌に対する (2009)
  • Author(s): 井上高光,小原崇,齋藤満,熊澤光明,成田伸太郎,堀川洋平,湯浅健,土谷順彦,佐藤滋,羽渕友則
  • Journal Title: Gemcitabine、Docetaxel、Carboplatin併用化学療法の検討泌尿器科紀要 Volume: 54 Pages: 581-585
• [Journal Article] 秋田大学における腹腔鏡下根治的膀胱摘除術の経験 (2009)
  • Author(s): 土谷順彦,井上高光,熊澤光明,齋藤満,小原崇,鶴田大,西尾浩二郎,湯浅健,佐藤滋,羽渕友則
  • Journal Title: Japanese Journal of Endourology and ESWL Volume: 21 Pages: 104-109
  • NAID: 10024372520
• [Journal Article] サイトカイン測定による泌尿器科腹腔鏡手術侵襲の検討 (2009)
  • Author(s): 熊澤光明,小原崇,鶴田大,齋藤満,井上高光,成田伸太郎,堀川洋平,湯浅健,土谷順彦,佐藤滋,羽渕友則
  • Journal Title: Japanese Journal of Endourology and ESWL Volume: 21 Pages: 369-373
  • NAID: 10024373077
• [Journal Article] ハンドアシスト後腹膜鏡下ドナー右腎摘出術の臨床的検討 (2009)
  • Author(s): 土谷順彦,成田伸太郎,井上高光,熊澤光明,齋藤満,小原崇,堀川洋平,湯浅健,松浦忍,佐藤滋,羽渕友則
  • Journal Title: Japanese Journal of Endourology and ESWL Volume: 22 Pages: 65-70
  • NAID: 10025319844
• [Journal Article] 前立腺癌のCTC (2009)
  • Author(s): 湯浅健
  • Journal Title: 前立腺癌のCTC Volume: 228 Pages: 1099-1104
• [Journal Article] 腎細胞癌に対する分子標的治療の展開 (2009)
  • Author(s): 湯浅健,土谷順彦,羽渕友則
  • Journal Title: 臨床泌尿器科 Volume: 63 Pages: 7-13
  • NAID: 40016432117
• [Journal Article] 進行性腎細胞癌治療の現状と将来 (2009)
  • Author(s): 大家基嗣,釜井隆男,中村英二郎,湯浅健,高橋正幸
  • Journal Title: 今できること!治療戦略と工夫Pharma Medica Volume: 27 Pages: 76-85
• [Journal Article] Intravesical administration of gammadelta T cells successfully prevents the growth of bladder cancer in the murine model (2009)
  • Author(s): 湯浅健, et al.
  • Journal Title: Cancer Immunol Immunother 58 Pages: 493-502
  • Peer Reviewed
• [Journal Article] Editorial Comment to docetaxel-based combination chemotherapy with zoledronate in hormone refractory prostate cancer (2009)
  • Author(s): 湯浅健
  • Journal Title: Int J Urol. 16 Pages: 731-732
  • Peer Reviewed
• [Journal Article] Clinical significance of a single nucleotide polymorphism and allelic imbalance of matrix metalloproteinase-1 promoter region in prostate cancer (2009)
  • Author(s): Tsuchiya N, et al.(9番目)
  • Journal Title: Oncol Rep. 22 Pages: 493-499
  • Peer Reviewed
• [Journal Article] Cystoprostatectomy as a treatment of prostate cancer involving the bladder neck (2009)
  • Author(s): Kumazawa, et al.(7番目)
  • Journal Title: Urol Int. 83 Pages: 141-145
  • Peer Reviewed
• [Journal Article] The novel tumor-suppressor Mel-18 in prostate cancer : its functional polymorphism, expression, and clinical significance (2009)
  • Author(s): Wang W, Yuasa T., et al.
  • Journal Title: Int J Cancer 125 Pages: 2836-2843
  • Peer Reviewed
• [Journal Article] 治療薬解説 エベロリムス (2009)
  • Author(s): 湯浅健
  • Journal Title: カレントテラピー 27 Pages: 64-69
• [Journal Article] 前立腺癌のCTC-血清PSA値の限界と新規バイオマーカーCTC- (2009)
  • Author(s): 湯浅健
  • Journal Title: 医学の歩み 228 Pages: 1099-1103
• [Journal Article] Clinical Efficacy and Prognostic Factors for Overall Survival in Japanese Patients with Metastatic Renal Cell Cancer Treated with Sunitinib
  • Author(s): Yuasa T, Tsuchiya N, Horikawa Y, Narita S, Inoue T, Urakami S, Yamamoto S, Yonese J, Takahashi S, Hatake K, Fukui I. Habuchi T
  • Journal Title: BJU int Volume: (in press)
• [Journal Article] Identification of ALK fusions in renal cancer : Large-scale immunohistochemical screening by intercalated antibody-enhanced polymer method
  • Author(s): Sugawara S, Togashi Y, Kuroda N, Sakata S, Hatano S, Asaka R, Yuasa T, Yonese J, Kitagawa M, Mano H, Ishikawa Y, Takeuchi K
  • Journal Title: Cancer Volume: (in press)
• [Journal Article] Biomarkers to Predict Response to Sunitinib Therapy and Prognosis in Metastatic Renal Cell Cancer
  • Author(s): Yuasa T, Takahashi S, Hatake K, Yonese J, Fukui I
  • Journal Title: Cancer Science Volume: 102 Pages: 1949-57
  • NAID: 10030244632
• [Journal Article] Molecular targeted therapies for patients with metastatic renal cell cancer
  • Author(s): Yuasa T, Fujii Y, Takahashi S, Fukui I, Yonese J
  • Journal Title: Translational Med Volume: (in press)
• [Presentation] 転移性腎細胞がんに対する分子標的治療のupdate(セミナー) (2011)
  • Author(s): 湯浅健
  • Organizer: 第59回日本泌尿器科学会東部総会
  • Place of Presentation: 横浜
  • Year and Date: 2011-10-22
• [Presentation] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function (2011)
  • Author(s): Yuasa T, et al.Tokyo, 2011
  • Organizer: The 8th Asia Pacific Oncology Summit
  • Place of Presentation: 東京
  • Year and Date: 2011-03-24
• [Presentation] (2011)
  • Author(s): 湯浅健
  • Organizer: 第34回骨を語る会
  • Place of Presentation: 弘前
  • Year and Date: 2011-02-10
• [Presentation] 転移性腎細胞がんに対する治療戦略 (2011)
  • Author(s): 湯浅健
  • Organizer: 腎細胞がんセミナー
  • Place of Presentation: 東京
  • Year and Date: 2011-01-17
• [Presentation] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function (2011)
  • Author(s): Yuasa T, Maita S, Tsuchiya N, Hatake K, Fukui I, Kimura S, Maekawa T, Habuchi T
  • Organizer: The 8th Asia Pacific Oncology Summit
  • Place of Presentation: Tokyo
• [Presentation] Clinical Characteristics of Xp11.2 Translocation Renal Cell Carcinoma in Adult Japanese Patients (2011)
  • Author(s): Numakura K, Tsuchiya N, Yuasa T, Inoue T, Narita S, Horikawa Y, Hatakeyama S, Ohyama C, Inoue T, Mimata H, Saito H, Arai Y, Kanno T, Kamba T, Ogawa O, Habuchi T
  • Organizer: The 105^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: Washington DC
• [Presentation] Prognostic Impact of Pretreatment C-Reactive Protein for Patients with Metastatic Renal Cell Carcinoma treated with Tyrosine Kinase Inhibitors (2011)
  • Author(s): Yasuda Y, Saito K, Sukegawa G, Ito M, Kubo Y, Yano A, Kitsukawa S, Yuasa T, Urakami S, Yamamoto S, Yonese J, Takahashi S, Fukui I
  • Organizer: The 105^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: Washington DC
• [Presentation] Stage C(cT3N0M0)前立腺癌の中期治療成績-前立腺全摘術vs放射線療法- (2011)
  • Author(s): 山本真也、米瀬淳二、浦上慎司、吉川慎一、矢野晶大、久保雄一、伊藤将也、助川玄、安田庸輔、湯浅健、河野敦、石川雄一、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] 転移性腎細胞癌における分子標的治療-腫瘍縮小および予後予測因子の検討- (2011)
  • Author(s): 湯浅健、土谷順彦、浦上慎司、堀川洋平、成田伸太郎、井上高光、仲野兼司、高橋俊二、畠清彦、山本真也、米瀬淳二、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] ハイリスク前立腺癌に対する血管処理先行順行性広範前立腺全摘術の術者別治療成績 (2011)
  • Author(s): 久保雄一、山本真也、安田庸輔、助川玄、伊藤将也、矢野晶大、吉川慎一、湯浅健、浦上慎司、米瀬淳二、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] C反応性蛋白質は分子標的薬により治療された転移を有する腎細胞がんの予後予測因子である (2011)
  • Author(s): 安田庸輔、齋藤一隆、助川玄、伊藤将也、久保雄一、矢野晶大、吉川慎一、湯浅健、浦上慎司、山本真也、米瀬淳二、高橋俊二、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] 前立腺針生検における癌検出予測因子としてのOveractive Bladder Symptom Scoreの有用性 (2011)
  • Author(s): 伊藤将也、増田均、安田庸輔、助川玄、久保雄一、矢野晶大、吉川慎一、浦上慎司、湯浅健、山本真也、米瀬淳二、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] 去勢抵抗性前立腺癌に対する結合型エストロゲン製剤のパイロット試験 (2011)
  • Author(s): 浦上慎司、米瀬淳二、山本真也、湯浅健、吉川慎一、矢野晶大、久保雄一、伊藤将也、助川玄、安田庸輔、福井巖
  • Organizer: 第99回日本泌尿器科学会総会
  • Place of Presentation: 名古屋
• [Presentation] 小径腎腫瘍の病理所見と解剖学的因子の関連について (2011)
  • Author(s): 安田庸輔,藤井靖久,湯浅健,助川玄,伊藤将也,久保雄一,吉川慎一,浦上慎司,山本真也,米瀬淳二,福井巖
  • Organizer: 第49回日本癌治療学会
• [Presentation] 前立腺全摘標本におけるNon Specimen Confinementの術前予測因子の検討 (2011)
  • Author(s): 山本真也,川上理,米瀬淳二,浦上慎司,吉川慎一,矢野晶大,久保雄一,伊藤将也,助川玄,安田庸輔,湯浅健,河野敦,石川雄一,福井巌
  • Organizer: 第49回日本癌治療学会
• [Presentation] がん研有明病院におけるpN1前立腺癌の検討 (2011)
  • Author(s): 浦上慎司,米瀬淳二,山本真也,湯浅健,吉川慎一,矢野晶大,久保雄一,伊藤将也,助川玄,安田庸輔,福井巌
  • Organizer: 第49回日本癌治療学会
• [Presentation] 転移性腎細胞癌の治療前腫瘍径とスニチニブの効果予測 (2011)
  • Author(s): 米田真也,湯浅健,沼倉一幸,鶴田大,小原崇,井上高光,成田伸太郎,堀川洋平,土谷順彦,佐藤滋,福井巌,米瀬淳二,畠清彦,高橋俊二,羽渕友則
  • Organizer: 第49回日本癌治療学会
• [Presentation] 術者間における片側神経温存前立腺全摘除術後の性機能回復の比較 (2011)
  • Author(s): 山本真也,米瀬淳二,浦上慎司,吉川慎一,矢野晶大,久保雄一,伊藤将也,助川玄,安田庸輔,湯浅健,福井巌
  • Organizer: 日本性機能学会
• [Presentation] スーテントの転移性腎細胞癌患者における海外第三相試験および国内第二相試験結果のサブ解析 (2011)
  • Author(s): 赤座英之,篠原信雄,湯浅健,冨田善彦,藤元博行,庭川要,麦谷荘一,大園誠一郎,三木恒治,植村天受,野々村祝夫,高橋正幸,長谷川淑博,縣直樹,狩野宗英,植田英治,柴田篤,河合統介,内藤誠二
  • Organizer: 肺単独転移に対するスーテントの抗腫瘍効果腎癌研究会
• [Presentation] 腎細胞癌に対する分子標的治療の有害事象対策 (2011)
  • Author(s): 高橋俊二,仲野兼司,湯浅健,畠清彦,樋口秀太郎,戸谷渡,杉崎崇人,濱敏弘
  • Organizer: チーム医療腎癌研究会
• [Presentation] 去勢抵抗性前立腺癌に対する結合型エストロゲン製剤(プレマリン)パイロット試験 (2011)
  • Author(s): 浦上慎司,米瀬淳二,山本真也,湯浅健,吉川慎一,矢野晶大,久保雄一,伊藤将也,助川玄,安田庸輔,福井巖
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] 前立腺針生検における癌検出予測因子としてのoveractive bladder symptom score(OABSS)の有用性 (2011)
  • Author(s): 伊藤将也,増田均,安田庸輔,助川玄,久保雄一,矢野晶大,吉川慎一,浦上慎司,湯浅健,山本真也,米瀬淳二,福井巖
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] C反応性蛋白(CRP)は分子標的薬により治療された転移を有する腎細胞癌の予後予測因子である (2011)
  • Author(s): 安田庸輔,齋藤一隆,助川玄,伊藤将也,久保雄一,矢野晶大,吉川慎一,湯浅健,浦上慎司,山本真也,米瀬淳二,高橋俊二,福井巖
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] 骨転移への挑戦ゾレドロン酸の多彩な抗腫瘍作用 (2010)
  • Author(s): 湯浅健
  • Organizer: 倉敷Bone Health Meeting 2010
  • Place of Presentation: 倉敷
  • Year and Date: 2010-11-25
• [Presentation] 骨転移の治療骨転移を認めた腎がん患者の治療成績 (2010)
  • Author(s): 湯浅健, 他
  • Organizer: 第48回日本癌治療学会
  • Place of Presentation: 京都
  • Year and Date: 2010-10-29
• [Presentation] 転移性腎細胞がんに対する治療戦略 (2010)
  • Author(s): 湯浅健
  • Organizer: 滋賀腎細胞癌学術講演会
  • Place of Presentation: 大津
  • Year and Date: 2010-10-14
• [Presentation] 去勢抵抗性前立腺がんに対する化学療法 (2010)
  • Author(s): 湯浅健
  • Organizer: 第17回東京前立腺フォーラム
  • Place of Presentation: 東京
  • Year and Date: 2010-10-09
• [Presentation] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function. (2010)
  • Author(s): Maita S, Yuasa T, et al.
  • Organizer: The 104^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: San Francisco
  • Year and Date: 2010-03-15
• [Presentation] Relationship between bone mineral density and androgen-depr-ivation therapy in Japanese prostate cancer patients. (2010)
  • Author(s): Yuasa T., et al.
  • Organizer: The 104^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: San Francisco
  • Year and Date: 2010-03-15
• [Presentation] 骨転移への挑戦 ゾレドロン酸の多彩な抗腫瘍作用 (2010)
  • Author(s): 湯浅健
  • Organizer: Urology Bone Disease Forum
  • Place of Presentation: 東京
  • Year and Date: 2010-01-22
• [Presentation] Antitumor effect of sunitinib against skeletal metastatic renal cell carcinoma through inhibition of osteoclast function (2010)
  • Author(s): Maita S, Yuasa T, et al
  • Organizer: The 104^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: San Francisco
• [Presentation] Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients (2010)
  • Author(s): Yuasa T, Maita S, et al
  • Organizer: The 104^<th> Annual Meeting of American Association of Urology
  • Place of Presentation: San Francisco
• [Presentation] 癌研有明病院における進行期腎細胞癌に対する分子標的治療の初期経験 (2010)
  • Author(s): 湯浅健,、仲野兼司、高橋俊二,畠清彦,米瀬淳二,福井巖
  • Organizer: 第8回日本臨床腫瘍学会総会
  • Place of Presentation: 東京
• [Presentation] 癌研有明病院における進行期腎細胞癌に対する分子標的治療の初期経験 (2010)
  • Author(s): 湯浅健,浦上慎司,吉川慎一,山本真也,沼尾昇,久保雄一,伊藤将也,仲野兼司,公平誠,高橋俊二,畠清彦,米瀬淳二,福井巖
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 日本人腎細胞癌患者におけるスニチニブ単剤投与の全生存期間第II相臨床試験(第2報) (2010)
  • Author(s): 高橋正幸,藤元博行,植村天受,篠原信雄,冨田善彦,庭川要,湯浅健,長谷川淑博,麦谷荘一,野々村祝夫,三木恒治,内藤誠二,赤座英之
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 進行性腎細胞癌に対するスニチニブの腫瘍縮小効果と副作用との関連 (2010)
  • Author(s): 堀川洋平,土谷順彦,小原崇,沼倉一幸,鶴田大,齋藤満,成田伸太郎,湯浅健,佐藤滋,羽渕友則
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 生検Gleason score 8以上の前立腺癌に対する前立腺全摘術の治療成績 (2010)
  • Author(s): 沼尾昇,山本真也,安田庸輔,助川玄,伊藤将也,久保雄一,吉川慎一,湯浅健,浦上慎司,米瀬淳二,石川雄一,福井巌
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 腎細胞癌骨転移に対するスニチニブの増殖阻害効果 (2010)
  • Author(s): 米田真也,湯浅健,土谷順彦,馬智勇,鶴田大,齋藤満,熊澤光明,成田伸太郎,堀川洋平,畠清彦,木村晋也,前川平,羽渕友則
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 内分泌不応性前立腺癌に対するドセタキセル化学療法における予後因子の検討 (2010)
  • Author(s): 伊藤将也,齋藤一隆,湯浅健,安田庸輔,助川玄,久保雄一,沼尾昇,吉川慎一,浦上慎司,山本真也,米瀬淳二,福井巖
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 盛岡
• [Presentation] 再燃前立腺癌の治療戦略再燃前立腺癌の治療戦略骨転移への対応, pN+前立腺癌における内分泌療法開始時期に関する検討 (2010)
  • Author(s): 米瀬淳二,山本真也,浦上慎司,吉川慎一,沼尾昇,湯浅健,久保雄一,伊藤将也,助川玄,福井巖
  • Organizer: 第98回日本泌尿器科学会総会,第48回日本癌治療学会総会
  • Place of Presentation: 盛岡,京都
• [Presentation] 骨転移の治療骨転移を認めた腎がん患者の治療成績 (2010)
  • Author(s): 湯浅健,安田庸輔,助川玄,伊藤将也,久保雄一,沼尾昇,吉川慎一,浦上慎司,山本真也,米瀬淳二,福井巌
  • Organizer: 第48回日本癌治療学会総会
  • Place of Presentation: 京都
• [Presentation] 膀胱癌に対する膀胱全摘除術後上部尿路再発の頻度と危険因子の検討 (2010)
  • Author(s): 助川玄,沼尾昇,山本真也,安田庸輔,伊藤将也,久保雄一,吉川慎一,湯浅健,浦上慎司,米瀬淳二,福井巌
  • Organizer: 第75回日本泌尿器科学会東部総会
  • Place of Presentation: 宇都宮
• [Presentation] 膀胱癌に対する血管茎処理先行広範膀胱全摘後の局所再発に関する検討 (2010)
  • Author(s): 安田庸輔,山本真也,助川玄,伊藤将也,久保雄一,沼尾昇,吉川慎一,湯浅健,浦上慎司,米瀬淳二,福井巖
  • Organizer: 第75回日本泌尿器科学会東部総会
  • Place of Presentation: 宇都宮
• [Presentation] エストロゲンおよびSERMと骨代謝作用新たな視点からアロマターゼ阻害剤および抗アンドロゲン剤による骨代謝障害 (2010)
  • Author(s): 高橋俊二,湯浅健,畠清彦
  • Organizer: 第27回日本骨代謝学会学術集会
• [Presentation] 片側神経温存前立腺全摘除術後の性機能変化 (2010)
  • Author(s): 山本真也,米瀬淳二,浦上慎司,吉川慎一,沼尾昇,久保雄一,伊藤将也,助川玄,安田庸輔,湯浅健,福井巌
  • Organizer: 日本性機能学会総会
• [Presentation] 進行期腎細胞癌に対する分子標的治療の初期経験 (2010)
  • Author(s): 湯浅健,、仲野兼司、高橋俊二,畠清彦,米瀬淳二,福井巖
  • Organizer: 第8回日本臨床腫瘍学会総会
  • Place of Presentation: 東京
• [Presentation] 臨床病期T1腎癌の手術術式選択に及ぼす腫瘍側因子と手術合併症の検討 (2010)
  • Author(s): 安田庸輔,湯浅健,助川玄,伊藤将也,久保雄一,沼尾昇,吉川慎一,浦上慎司,山本真也,米瀬淳二,福井巌
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] 前立腺癌患者の骨密度に関する検討 (2010)
  • Author(s): 米田真也,湯浅健,小峰直樹,高橋誠,沼倉一幸,鶴田大,小原崇,齋藤満,成田伸太郎,堀川洋平,土谷順彦,佐藤滋,羽渕友則
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] 排尿障害を合併した前立腺癌に対する前立腺全摘術後の排尿状態についての検討 (2010)
  • Author(s): 山本真也,米瀬淳二,浦上慎司,吉川慎一,沼尾昇,久保雄一,伊藤将也,助川玄,安田庸輔,湯浅健,福井巌
  • Organizer: 日本泌尿器科学会東部総会
• [Presentation] 転移性腎細胞癌に対する治療戦略 (2009)
  • Author(s): 湯浅健
  • Organizer: スーテント発売1周年記念公演
  • Place of Presentation: 宇都宮市
  • Year and Date: 2009-11-07
• [Presentation] 骨転移セミナー 泌尿器領域における骨転移とビスフォスフォネート剤の展望 (2009)
  • Author(s): 湯浅健
  • Organizer: 第47回 日本癌治療学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2009-10-23
• [Presentation] 日本人前立腺癌患者の内分泌療法と骨密度 (2009)
  • Author(s): 湯浅健, 他
  • Organizer: 第47回 日本癌治療学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2009-10-23
• [Presentation] The novel tumor-suppressor Mel-18 in prostate cancer : its functional polymorphism, expression, and clinical significance (2009)
  • Author(s): 湯浅健, 他
  • Organizer: 第66回 日本癌学会学術総会
  • Place of Presentation: 横浜市
  • Year and Date: 2009-10-01
• [Presentation] 腎細胞癌骨転移に対するスニチニブの増殖阻害効果 (2009)
  • Author(s): 湯浅健, 他
  • Organizer: 第13回日本がん分子標的学会総会
  • Place of Presentation: 徳島市
  • Year and Date: 2009-06-25
• [Presentation] The novel tumor-suppressor Mel-18 in prostate cancer : its functional polymorphism, expression, and clinical significance (2009)
  • Author(s): Wang W, Yuasa T, et al.
  • Organizer: The 103rd Annual meeting of the American Urological Association
  • Place of Presentation: Cicago
  • Year and Date: 2009-05-15
• [Presentation] 日本人前立腺癌患者における内分泌療法による骨密度低下 (2009)
  • Author(s): 湯浅健, 他
  • Organizer: 第98回日本泌尿器科学会総会
  • Place of Presentation: 岡山市
  • Year and Date: 2009-04-16
• [Presentation] The novel tumor-suppressor Mel-18 in prostate cancer : its functional polymorphism, expression, and clinical significance (2009)
  • Author(s): Wang W, Yuasa T, et al
  • Organizer: The 103rd Annual meeting of the American Urological Association
  • Place of Presentation: Chicago
• [Presentation] A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer (2009)
  • Author(s): Narita N, Yuasa T, et al
  • Organizer: The 103rd Annual meeting of the American Urological Association
  • Place of Presentation: Chicago
• [Presentation] 腎細胞癌骨転移に対するスニチニブの効果 (2009)
  • Author(s): 湯浅健、米田真也、土谷順彦、羽渕友則
  • Organizer: 日本臨床腫瘍学会総会
  • Place of Presentation: 名古屋
• [Presentation] 骨転移を有する前立腺癌の予後におけるhGH、IGF、IL-6ならびにその受容体遺伝子多型の関与 (2009)
  • Author(s): 土谷順彦,成田伸太郎,熊澤光明,馬智勇,堀川洋平,鶴田大,齋藤満,湯浅健,佐藤滋,斎藤誠一,荒井陽一,小川修,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] 膀胱癌におけるRANTES多型の影響 (2009)
  • Author(s): 鶴田大,成田伸太郎,齋藤満,熊澤光明,堀川洋平,湯浅健,佐藤滋,土谷順彦,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] ハイリスク前立腺癌に対するネオアジュバント内分泌化学療法の試み (2009)
  • Author(s): 熊澤光明,鶴田大,齋藤満,成田伸太郎,堀川洋平,湯浅健,土谷順彦,佐藤滋,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] ホルモン抵抗性前立腺癌に対するDocetaxel、Estramustine phosphate、Carboplatin併用療法の治療成績 (2009)
  • Author(s): 成田伸太郎,鶴田大,齋藤満,熊澤光明,堀川洋平,湯浅健,佐藤滋,土谷順彦,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] ドナー側因子から見た移植後早期腎機能発現遅延についての検討 (2009)
  • Author(s): 齋藤満,佐藤滋,三浦喜子,鶴田大,熊澤光明,成田伸太郎,堀川洋平,湯浅健,土谷順彦,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] 移植早期の高齢者レシピエントにおけるタクロリムス(TAC)、セルセプト(MMF)、プレドニゾロン(PDS)の薬物動態 (2009)
  • Author(s): 佐藤滋,齋藤満,鶴田大,熊澤光明,成田伸太郎,堀川洋平,湯浅健,土谷順彦,三浦昌朋,加賀谷英彰,鈴木敏夫,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] 日本人前立腺癌患者における内分泌療法による骨密度変化 (2009)
  • Author(s): 湯浅健,米田真也,土谷順彦,馬智勇,鶴田大,齋藤満,成田伸太郎,熊澤光明,堀川洋平,佐藤滋,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] 前立腺癌におけるchromogranin Aならびにendothelin-1の臨床的意義 (2009)
  • Author(s): 馬智勇,土谷順彦,湯浅健,成田伸太郎,堀川洋平,熊澤光明,鶴田大,齋藤満,河田真子,井上高光,佐藤滋,小川修,羽渕友則
  • Organizer: 第97回日本泌尿器科学会総会
  • Place of Presentation: 岡山
• [Presentation] 腎細胞癌骨転移に対するスニチニブの効果 (2009)
  • Author(s): 湯浅健,米田真也,土谷順彦,馬智勇,鶴田大,齋藤満,熊澤光明,成田伸太郎,堀川洋平,畠清彦,木村晋也,前川平,羽渕友則
  • Organizer: 第13回日本がん分子標的学会総会,第66回日本癌学会学術総会
  • Place of Presentation: 徳島,横浜
• [Presentation] 前立腺癌における新規腫瘍抑制因子Mel-18機能的多様性、発現、臨床的意義 (2009)
  • Author(s): 湯浅健,王尉,米田真也,土谷順彦,成田伸太郎,堀川洋平,熊澤光明,井上高光,鶴田大,齋藤満,福井巌,畠清彦,羽渕友則
  • Organizer: 第66回日本癌学会学術総会
  • Place of Presentation: 横浜
• [Presentation] 秋田大学における進行性腎細胞癌に対するsunitinibの初期使用経験 (2009)
  • Author(s): 土谷順彦、湯浅健,堀川洋平,成田伸太郎,熊澤光明,鶴田大,小原崇,沼倉一幸,米田真也,佐藤滋,羽渕友則
  • Organizer: 第47回日本癌治療学会総会
  • Place of Presentation: 横浜
• [Presentation] 転移性尿路上皮癌に対するGEP療法 (2009)
  • Author(s): 浦上慎司,米瀬淳二,山本真也,湯浅健,齋藤一隆,吉川慎一,須山太助,久保雄一,伊藤将也,助川玄,福井巌
  • Organizer: 第47回日本癌治療学会総会
  • Place of Presentation: 横浜
• [Presentation] 日本人前立腺癌患者の内分泌療法と骨密度 (2009)
  • Author(s): 湯浅健,米田真也,土谷順彦,成田伸太郎,馬智勇,米瀬淳二,福井巌,羽渕友則
  • Organizer: 第47回日本癌治療学会総会
  • Place of Presentation: 横浜
• [Book] 最新化学療法レジメン泌尿器がん (2012)
  • Author(s): 湯浅健(編)
  • Total Pages: 87
  • Publisher: メジカルビュー社
• [Book] 膀胱癌・病因新しい診断と治療のABC腎癌・膀胱癌 (2011)
  • Author(s): 湯浅健、羽渕友則
  • Publisher: 最新医学社
• [Book] 腎がん・尿路がん・膀胱がんがん化学療法の進歩 (2011)
  • Author(s): 湯浅健、羽渕友則
  • Publisher: 医薬ジャーナル社
• [Book] 最新化学療法レジメン泌尿器がん (2011)
  • Author(s): 湯浅健
  • Publisher: メジカルビュー社
• [Book] 泌尿器腫瘍の化学療法腫瘍内科オリエンテーション (2010)
  • Author(s): 湯浅健
  • Publisher: 医薬ジャーナル社
• [Book] 前立腺癌腫瘍内科ゴールデンハンドブック (2010)
  • Author(s): 湯浅健
  • Publisher: 南江堂
• [Book] 泌尿器がんがん化学療法・分子標的治療update (2009)
  • Author(s): 湯浅健、羽渕友則
  • Publisher: 中外医学社
• [Book] がん化学療法・分子標的治療 update(一部のみ執筆) (2009)
  • Author(s): 湯浅健, 羽渕友則
  • Total Pages: 733
  • Publisher: 中外医薬社
• [Book] 泌尿器腫瘍の化学療法(一部のみ執筆) (2009)
  • Author(s): 湯浅健
  • Total Pages: 287
  • Publisher: 医薬ジャーナル社