Identification of molecules associated with intravesical recurrence of non-muscle invasive bladder cancer and the development of novel therapeutic strategy based on the molecular mechanism
Project/Area Number |
21592045
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Urology
|
Research Institution | Kobe University |
Principal Investigator |
MIYAKE Hideaki 神戸大学, 大学院・医学研究科, 准教授 (60379435)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 表在性膀胱癌 / 再発 / 細胞周期 / 細胞接着 / EMT / siRNA / HSP70 / 血管新生 / カドヘリン / p27 / β4 interin / eithelial-to-mesenhymal transition / 免疫組織化学染色 / 再発予防 / β4 integrin / epithelial-to-mesenhymal transition |
Research Abstract |
Through the evaluation of molecules associated with cell cycle, cell adherence and EMT, we developed predictive systems for intravesical recurrence of non-muscle invasive bladder cancer. In addition, we suggested the usefulness of novel therapeutic strategy targeting these molecules for preventing intravesical recurrence of non-muscle invasive bladder cancer.
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Report
(4 results)
Research Products
(18 results)