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Assessments of autonomic nervous system activity of the fetus andthe prenatal education by fetal magnetocardiography.

Research Project

Project/Area Number 21592105
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionIwate Medical University

Principal Investigator

FUKUSHIMA Akimune  岩手医科大学, 医学部, 教授 (20208937)

Co-Investigator(Kenkyū-buntansha) NAKAI Kenji  岩手医科大学, 歯学部歯科内科学, 教授 (90146035)
KOBAYASHI Kouichirou  岩手大学, 工学部, 准教授 (60277233)
Co-Investigator(Renkei-kenkyūsha) NISHIGORI Hidekazu  東北大学, 医学部, 講師 (40453310)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords胎児 / 新生児自律神経活動 / 胎教 / 胎児心磁図 / 胎児心拍変動 / 胎児中枢神経 / 胎児中枢神経活動
Research Abstract

The value of CV_<RR> in the normal pregnancy group displayed a slight increasing trend with gestational age. However, no such trend was observed in the FGR group. In contrast, the LF/HF ratio in the normal pregnancy group clearly increased over the gestational period. The LF/HF ratio in the FGR group also displayed an increasing trend over the gestational period. The development of fetal ANS activity in FGR cases might differ from that observed in the normal pregnancy group. With regard to fetal autonomic nervous system activity, there was a pronounced increase in sympathetic nervous activity among fetuses with normal growth in the second half of pregnancy. LH/HF ratio of fetuses and mothers both decreased by the music relaxations.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (23 results)

All 2011 2010 2009

All Journal Article (11 results) (of which Peer Reviewed: 4 results) Presentation (12 results)

  • [Journal Article] Assessment of fetal autonomic nervous system activity by fetal magnetocardiography : Comparison of normal pregnancy2011

    • Author(s)
      Akimune Fukushima, Kenji Nakai, Tomonobu Kanasugi, Miyuki Terata, Toru Suginayama
    • Journal Title

      Journal of Pregnancy

    • Related Report
      2011 Final Research Report
  • [Journal Article] Assessment of fetal autonomic nervous system activity by fetal magnetocardiography : Comparison of normal pregnancy and intrauterine growth restriction2011

    • Author(s)
      Akimune Fukushima, Kenji Nakai, Tomonobu Kanasugi, et al
    • Journal Title

      Journal of Pregnancy

      Volume: 2011 Pages: 1-6

    • DOI

      10.1155/2011/218162

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prenatal diagnosis of polymorphic ventricular tachycardia using 64-channel magnetocardiography2010

    • Author(s)
      Akimune Fukushima, Kenji Nakai, Atsushi Matsumoto, Janette Strasburger, Toru Sugiyama
    • Journal Title

      Heart and Vessels

      Volume: 25 Pages: 270-273

    • Related Report
      2011 Final Research Report
  • [Journal Article] Prenatal diagnosis of polymorphic ventricular tachycardia using 64 channel mapnetocardiography2010

    • Author(s)
      Akimune Fukushima, et al.
    • Journal Title

      Heart and Vessels

      Volume: 25 Pages: 270-273

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 64チャンネル心磁図による胎児不整脈診断と胎内治療2010

    • Author(s)
      福島明宗, 他
    • Journal Title

      日本生体磁気学会誌特別号

      Volume: 23 Pages: 70-71

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 周産期モニタリングUP to DATEとその応用2009

    • Author(s)
      福島明宗、中居賢司
    • Journal Title

      心磁図による各種胎児診断周産期医学

      Volume: 3(4) Pages: 465-470

    • Related Report
      2011 Final Research Report
  • [Journal Article] Clinical Significance of 64-channel Magnetocardiography(MCG)-Three-dimensional analysis high frequency magnetic field of the terminal QRS-end and spectral map of atrial fibrillation-2009

    • Author(s)
      Nakai k, Takahashi K, Okabayashi H, Fukushima A, Itoh M, Kobayashi K, Yoshizawa M
    • Journal Title

      日本生体磁気学会誌特別号

      Volume: 22(1) Pages: 100-101

    • Related Report
      2011 Final Research Report
  • [Journal Article] Development and significance of a fetal electrocardiogram recorded by signal-averaged high-amplification2009

    • Author(s)
      Risa Hayashi, Kenji Nakai, Akimune Fukushima, Manabu Itoh, Toru Sugiyama
    • Journal Title

      Int Heart J

      Volume: 50(2) Pages: 161-171

    • Related Report
      2011 Final Research Report
  • [Journal Article] 周産期モニタリングUP to DATEとその応用 心磁図による各種胎児診断2009

    • Author(s)
      福島明宗、中居賢司
    • Journal Title

      周産期医学 3

      Pages: 465-470

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Development and significance of a fetal electrocardiogram recorded by signal-averaged high-amplification electrocardiography.2009

    • Author(s)
      Risa Hayashi, Kenji Nakai, Akimune Fukushima, Manabu Itoh, Toru Sugiyama
    • Journal Title

      Int Heart J 50

      Pages: 161-171

    • NAID

      130000108082

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Betamethasone and Mifeprostone (RU486) on Brain Acetylcolinesterase of Developing Chick Embryos.2009

    • Author(s)
      Sumire Yamate, Hidekazu Nishigori, Seishi Kishimoto, Yu Tezuka, Akimune Fukushima, Toru Sugiyama, Hideo Nishigori
    • Journal Title

      The Journal of Obstetrics and Gynecology Research 36

      Pages: 11-18

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Assesment of fetal aut s ystem activity by fetal magnetocardiography : comparison of normal pregnancy and intrauterine growth restriction2011

    • Author(s)
      A. Fukushima
    • Organizer
      The XXII Asian and Oceanic Congress of Obstetrics and Gynecology
    • Place of Presentation
      TAIPEI
    • Related Report
      2011 Final Research Report
  • [Presentation] Assessment of fetal autonomic nervous system activity by fetal magnetocardiography : comparison of normal pregnancy and intrauterine growth restriction2011

    • Author(s)
      Akimune Fukushima
    • Organizer
      The XXII Asian and Oceanic Congress of Obstetrics and Gynecology
    • Place of Presentation
      TAIPEI
    • Related Report
      2011 Annual Research Report
  • [Presentation] Accurate Prenatal Diagnosis and Therapeutic Strategy of Fetal Arrhythmia by 64-Channel Magnetocardiography2010

    • Author(s)
      Akimune Fukushima
    • Organizer
      The 3^<rd> Asia Symposium on Magnetocardiography
    • Place of Presentation
      Tsukuba(Japan)
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 64channel心磁図による胎児不整脈診断とその治療2010

    • Author(s)
      福島明宗, 他
    • Organizer
      第27回日本心電図学会学術集会
    • Place of Presentation
      大分市
    • Year and Date
      2010-10-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 64チャンネル心磁図による胎児不整脈診断と胎内治療2010

    • Author(s)
      福島明宗, 他
    • Organizer
      第25回日本生体磁気学会
    • Place of Presentation
      柏市
    • Year and Date
      2010-07-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胎児心磁図による胎児不整脈診断と胎内治療2010

    • Author(s)
      福島明宗, 他
    • Organizer
      第46回日本周産期新生児医学会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-07-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 胎児心磁図による胎児不整脈診断と胎内治療2010

    • Author(s)
      福島明宗
    • Organizer
      第46回日本周産期新生児医学会
    • Place of Presentation
      神戸
    • Related Report
      2011 Final Research Report
  • [Presentation] 64チャンネル心磁図による胎児不整脈診断と胎内治療2010

    • Author(s)
      福島明宗
    • Organizer
      第25回日本生体磁気学会
    • Place of Presentation
      柏
    • Related Report
      2011 Final Research Report
  • [Presentation] 64channel心磁図による胎児不整脈診断とその治療2010

    • Author(s)
      福島明宗
    • Organizer
      第27回日本心電学会学術集会
    • Place of Presentation
      大分
    • Related Report
      2011 Final Research Report
  • [Presentation] Accuretae Prenatal Dignosis and T herapeutic Strategy of Fetal Arrhythmia by 64-Channel Magnetocardiography2010

    • Author(s)
      A. Fukushima
    • Organizer
      The 3rd Asia Symposium on Magnetocardiography
    • Place of Presentation
      Tsukuba
    • Related Report
      2011 Final Research Report
  • [Presentation] シンポジウム:Clinical Significance of 64-channel Magnetocardiography (MCG) -Three-dimmensional analysis high frequency magnetic field of the terminal QRS-end and spectral map of atrial fibrillation-2009

    • Author(s)
      Nakai k, Takahashi K, Okabayashi H, Fukushima A, Itoh M, Kobayashi K, Yoshizawa M
    • Organizer
      第24回日本生体磁気学会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2009-05-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] シンポジウム: Clinical Significance of 64-channel Magnetocardiography(MCG)-Three-dimensional analysis high frequency2009

    • Author(s)
      Nakai k, Takahashi K, Okabayashi H, Fukushima A, Itoh M, Kobayashi K, Yoshizawa M
    • Organizer
      第24回日本生体磁気学会
    • Place of Presentation
      金沢
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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