| Project/Area Number |
21592112
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Showa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUOKA Ryu 昭和大学, 医学部, 講師 (20349111)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | HIFU / 胎児治療 / 超音波診断 / 動物実験 / ファントム実験 |
|---|
| Research Abstract |
We conducted basic research on animal models and phantom experiment, which involved the application of HIFU to fetal treatment. This study, which investigated the optimum intensity and ultrasound frequency of HIFU, exposure time, effectiveness for arterial occlusion, and safety, led to the conclusion that we can apply HIFU to human fetuses. The Ethics Committee for Clinical Studies approved the procedure and consent was obtained from the patient after a full explanation. Although the procedure was not completely successful in this case, the possibility of inducing localized denaturation of human fetal tissue has been demonstrated for the first time, thus marking a step toward the future use of HIFU in fetal treatment.
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