Development of sensitivity test for anti-cancer agents by PET imaging : Try the imaging of P-glycoprotein in cell
| Project/Area Number |
21592125
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIYONO Yasusi 福井大学, 高エネルギー医学研究センター, 教授 (50305603)
KOTSUJI Fumikazu 福井大学, 医学部, 教授 (50153573)
YOSHIDA Yoshio 福井大学, 医学部, 准教授 (60220688)
SHIGAWA Akiko 福井大学, 医学部, 助教 (90444223)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 婦人科腫瘍学 / 抗癌剤 / 感受性試験 / PET / P糖蛋白 / シスプラチン / P糖たんぱく |
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| Research Abstract |
Our data indicated the possibility that two proteins(P-glycoprotein and hCtr-1) were target protein of sensitivity test for anti-cancer agents. And we weren' t able to get the success of making the molecular imaging drug for the proteins. We could resolve one of the mechanism for resistance of anti-cancer drugs and release the manuscriptpublication
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Report
(4 results)
Research Products
(5 results)
