Intraoperative diagnostic system for the metastasis of sentinel lymph node using the genetic technique
Project/Area Number |
21592200
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Otorhinolaryngology
|
Research Institution | Fukushima Medical University |
Principal Investigator |
MATSUZUKA Takashi 福島県立医科大学, 医学部・耳鼻咽喉科学講座, 講師 (80336461)
|
Co-Investigator(Kenkyū-buntansha) |
KOGURE Michhiko 福島県立医科大学, 医学部, 講師 (90264548)
MIURA Tomohiro 福島県立医科大学, 医学部, 助教 (00423806)
SUZUKI Masahiro 福島県立医科大学, 医学部, 助手 (90513268)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | センチネルリンパ節 / 扁平上皮癌 / 頭頸部癌 / 術中診断 / OSNA法 / サイトケラチン19 / 食道癌 |
Research Abstract |
One-step nucleic acid amplification(OSNA) is a new automated rapid system to detect lymph node metastasis using the genetic technique. The purpose of this study was to develop the OSNA method to identify lymph node metastasis in head and neck cancer. Analysis of 22 cases of head neck squamous cell carcinoma was performed with OSNA method and with routine histological examination. The OSNA and histological results were identical. According to this study, OSNA method has the potential to diagnose cervical node metastasis in head and neck cancer.
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Report
(4 results)
Research Products
(30 results)