the study of internalization of Haemophilus influenzae and Streptococcus pyogenes into epithelial cells in upper respiratory infectious disease.
Project/Area Number |
21592205
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Otorhinolaryngology
|
Research Institution | Wakayama Medical University |
Principal Investigator |
TOGAWA Akihisa 和歌山県立医科大学, 医学部, 講師 (70305762)
|
Co-Investigator(Kenkyū-buntansha) |
藤原 啓次 和歌山県立医科大学, 医学部, 准教授 (20244725)
島田 純 和歌山県立医科大学, 医学部, 講師 (90326372)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 咽頭科学 / 溶連菌 / 急性扁桃炎 / 急性鼻副鼻腔炎 / インフルエンザ菌 / 細胞内侵入 / 急性副鼻腔炎 / 急性中耳炎 |
Research Abstract |
Streptoococcus pyogenes and nontypeable Haemphyrus influenzae are important causative pathogens of upper respiratory infectious disease. To examine the internalization of these pathogens into human epithelial cells, we investigate the gene that may cause the internalization. We detected 12. 0% of sil gene in non-invasive infection and 17. 7% in invasive infection.
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Report
(3 results)
Research Products
(18 results)