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A study on establishment of new glaucoma diagnostic technologies.

Research Project

Project/Area Number 21592247
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionToho University

Principal Investigator

TOMITA Goji  東邦大学, 医学部, 教授 (30172191)

Co-Investigator(Kenkyū-buntansha) YAGI Fumihiko  東邦大学, 医学部, 講師 (40307765)
KITA Yoshiyuki  東邦大学, 医学部, 講師 (30349873)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords緑内障 / 臨床研究 / 光干渉断層計 / 網膜神経節細胞 / 視野
Research Abstract

We have demonstrated that the inner layer thickness of macular area retina, which had been enabled to be measured for the first time by spectral-domain optical coherence tomography, is a promising structural parameter for detecting early glaucoma, even in preperimetric condition. In addition, this structural parameter has been suggested to be useful for predicting prognosis of visual field progression in glaucoma.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (27 results)

All 2011 2010 2009

All Journal Article (10 results) (of which Peer Reviewed: 8 results) Presentation (15 results) Book (2 results)

  • [Journal Article] Variation in optic nerve head and macular structure with age and race with spectral-domain optical coherence tomography2011

    • Author(s)
      Girkin CA, McGwin G Jr, Sinai MJ, Sekhar GC, Figeret M, Wollstein G, Varma R, Greenfield D, Liebmann J, Araie M, Tomita G, Maeda N
    • Journal Title

      Garway-Heath DF(Ophthalmology)

      Volume: 118(12) Issue: 12 Pages: 2403-2408

    • DOI

      10.1016/j.ophtha.2011.06.013

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Glaucomtous eye macular ganglion cell complex thickness and its relation to temporal circumpapillary retinal nerve fiber layer thickness2011

    • Author(s)
      Kita Y, Kita R, Nitta A, Nishimura C, Tomita G
    • Journal Title

      Jpn J Ophthalmol

      Volume: 55 Issue: 3 Pages: 228-234

    • DOI

      10.1007/s10384-011-0017-3

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Macular retinal ganglion cell complex damage in the apparently normal visual field of gl ; aucomatous eyes with hemifield defects2011

    • Author(s)
      Takagi ST, Kita Y, Yagi F, Tomita G
    • Journal Title

      J Glaucoma

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Macular retinal ganglion cell complex and its relationship to the optic nerve head topography in glaucomatous eyes with hemifield defects2011

    • Author(s)
      Takagi S, Kita Y, Takeyama A, Tomita G
    • Journal Title

      Journal of Ophthalmology

      Pages: 914250-914250

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Macular retinal ganglion cell complex thickness and its relationship to the optic nerve head topography in glaucomatous eyes with hemifield defects.2011

    • Author(s)
      Takagi Seiji
    • Journal Title

      Journal of Ophthalmology

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 緑内障における眼底変化の特徴2010

    • Author(s)
      富田剛司
    • Journal Title

      日本眼科学会雑誌

      Volume: 114 Pages: 407-418

    • NAID

      10026261738

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] スペクトラルドメイン光干渉断層計と超音波角膜厚測定装置による中心角膜厚の比較2010

    • Author(s)
      徳江裕佳
    • Journal Title

      あたらしい眼科 27

      Pages: 91-94

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optovue RTVue-1002010

    • Author(s)
      北善幸
    • Journal Title

      臨床眼科 64

      Pages: 126-132

    • NAID

      40016986797

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 視神経乳頭陥凹の立体視判定と平面視判定の比較2009

    • Author(s)
      高木誠二、富田剛司
    • Journal Title

      あたらしい眼科

      Volume: 26 Pages: 1235-1238

    • NAID

      10027069290

    • Related Report
      2011 Final Research Report
  • [Journal Article] 視神経乳頭陥凹の立体視判定と平面視判定の比較2009

    • Author(s)
      高木誠二
    • Journal Title

      あたらしい眼科 26

      Pages: 1235-1238

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 正常眼圧緑内障における黄斑部網膜神経節細胞複合体厚と視野進行の関連2011

    • Author(s)
      安樂礼子、北善幸、高木誠二、榎本暢子、富田剛司
    • Organizer
      第22回日本緑内障学会
    • Place of Presentation
      秋田
    • Year and Date
      2011-09-24
    • Related Report
      2011 Final Research Report
  • [Presentation] 正常眼圧緑内障における黄斑部網膜神経節細胞複合体厚(GCC厚)と視野進行との関連2011

    • Author(s)
      安樂礼子
    • Organizer
      第22回日本緑内障学会
    • Place of Presentation
      秋田ビューホテル(秋田県)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] How to detect and confirm progression and use it to manage glaucoma2011

    • Author(s)
      Tomita G
    • Organizer
      World Glaucoma Congress
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-06-30
    • Related Report
      2011 Final Research Report
  • [Presentation] When to treat normal-tension glaucoma2011

    • Author(s)
      Tomita G
    • Organizer
      Asia Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-03-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Structure changes in the stressed nerve. WGA Symposium-stressed nerve-2011

    • Author(s)
      Tomita G
    • Organizer
      Asia Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-03-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Structure changes in the stressed nerve.2011

    • Author(s)
      Tomita Goji
    • Organizer
      Asia Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      シドニー国際会議場(オーストラリア)(招待講演)
    • Year and Date
      2011-03-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Treatment of normal-tension glaucoma2010

    • Author(s)
      Tomita G
    • Organizer
      The 13th Taipei international symposium of ophthalmology
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2011 Final Research Report
  • [Presentation] Peripapillary retinal nerve fiber layer thickness and macular area thickness in PAC eyes2009

    • Author(s)
      Tomita G
    • Organizer
      7th Asian Angle Closure Glaucoma Club Meeting
    • Place of Presentation
      Kuala Lumpur, Malasia
    • Year and Date
      2009-12-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Peripapillary retinal nerve fiber layer thickness and macular area thickness in PAC eyes2009

    • Author(s)
      Tomita Goji
    • Organizer
      7th Asian Angle Closure Glaucoma Club Meeting
    • Place of Presentation
      クアラルンプール、マレーシア
    • Year and Date
      2009-12-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] スペクトラルドメイン光干渉断層計RTVueによる網膜厚測定と緑内障性視野障害の関係性2009

    • Author(s)
      高木誠二
    • Organizer
      第20回日本緑内障学会
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2009-11-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 視神経乳頭部網膜神経線維層厚と黄斑部網膜内層厚の関連の解析2009

    • Author(s)
      北善幸
    • Organizer
      第63回日本臨床眼科学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2009-10-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ganglion cell complex layer measurements in macular region with Fourier domain optical cohenrence tomography in normative and glaucomatous eyes2009

    • Author(s)
      高木誠二
    • Organizer
      The 2nd World Glaucoma Congress
    • Place of Presentation
      ボストン、米国
    • Year and Date
      2009-07-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Spectral domain OCT2009

    • Author(s)
      Tomita Goji
    • Organizer
      The 2nd World Glaucoma Congress
    • Place of Presentation
      ボストン、米国
    • Year and Date
      2009-07-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Optic disc imaging in angle-closure glaucoma2009

    • Author(s)
      Tomita Goji
    • Organizer
      Asia-Pacific Ophthalmology Congress
    • Place of Presentation
      バリ、インドネシア
    • Year and Date
      2009-05-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] 緑内障眼における2種類の光干渉断層計(OCT)による網膜神経線維層厚2009

    • Author(s)
      野間謙晴
    • Organizer
      第13回日本眼科学会総会
    • Place of Presentation
      東京フォーラム
    • Year and Date
      2009-04-17
    • Related Report
      2009 Annual Research Report
  • [Book] Optic nerve head analysis In : Atlas of angle closure glaucoma Yamamoto T, Rojanapongpun P, Park KH(eds)2010

    • Author(s)
      Tomita G, Sihota R
    • Publisher
      Newest Medicine Publications
    • Related Report
      2011 Final Research Report
  • [Book] 緑内障診断の基本指針専門医のための眼科診療クオリファイ3緑内障診断ガイド2010

    • Author(s)
      富田剛司
    • Publisher
      中山書店
    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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